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500 个结果
  • 简介:会骑马不一定是唐僧,电可能是王子;会飞也不一定是菜鸟,或许恰是天使;生活中无时无刻不存在思维错觉与认知偏误,往往是忽略掉事物背后风景罪魁祸首。

  • 标签: 投资 首席执行官 企业家 经济学
  • 简介:在写这一篇有限文字时候,我又把郑敏先生《我春天到来》拿出来读了几遍,我依然被那深沉真挚情感深深感动,也依然赞叹于先生诗艺高超.其情感之深沉真挚,视野之高大宽阔,思想之幽深玄妙,如血肉骨骼融会贯通.你很难想象这是出自一位届望九之年老人诗篇.

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  • 简介:AIM:Tomeasurecentralcornealthickness(CCT)andpre-cornealtearfilmthicknessusingtheGalileidualScheimpfluganalyzer(GSA)inNewZealandWhiterabbits.METHODS:TennormalNewZealandWhiterabbits(20eyes)wereincludedinthisstudy.Withtheassistanceof0.1%fluorescein,thepre-cornealtearfilmcanbewellvisualized.BotheyesofeachrabbitwerescannedoncewiththeGSApre-andpost-instillationof1μL0.1%fluorescein.ThedifferencebetweenthetwomeasurementsofCCT(4-mmdiameter)wasrecordedasthepachymetricvaluesofthecentraltearfilm.RESULTS:TheCCTofpre-andpost-instillationwas388.8±9.5μmand407.0±10.5μm,respectively.Afterapairedt-testanalysis,thecentralpre-cornealtearfilmthicknessof4mmdiameterwas18.2±5.31μmwitha95%confidenceintervalof(15.7,20.6)μm(P<0.001).CONCLUSION:GSAcanbeusedtomeasureCCTandanalyzecentraltearfilmthicknessofrabbitswiththehelpoffluorescein.

  • 标签: TEAR film SCHEIMPFLUG rabbits central CORNEAL
  • 简介:B型KP方程族是一类重要物理模型,通过考虑平方特征函数对称,可以构造得到新推广B型KP方程族。借助于一些约束条件,可以研究新推广B型KP方程族约化问题,得到推广B型KP方程族与1+1维形变SK方程族之间联系。

  • 标签: B型KP方程族 可积形变 可积约化
  • 简介:AIM:Toinvestigatethecharacteristicsandcriterionofgraftrejectioninmicemodel.METHODS:C57BL/6orBALB/cmicecornealgraftsweregraftedontoBALB/chosts.Eachgroupwasdividedintotwosubgroupsaccordingtothecornealopacityscores12daftertransplantation.Thecharacteristicsofopacityandneovascularizationwereobserved.Miceofthe12th,50thdayaftertransplantation,thegraftsbiopsyofmiceinallogeneicgroup1,whichopacityscoreexceed3,werepreparedforhistologicalobservationandthoserestoretransparentwereendothelialstained.RESULTS:Therewasnodifferenceofcornealopacityscoreonthe7thand12thdayafteroperation;thehistologicalresultshadnodisparitybetweensyngeneicgroupandallogeneicgroup.Onthe12thdayaftersurgery,theturbiditycurvewasapparentingraftswithopacityscore<2.Mononuclearcellswereshowningraftswithopacityscorereached3inallogeneicgroup1.Differentrejectionperformancewasobservedintissuesectionsonthe50thdayaftersurgery.CONCLUSION:Grafts,opacityscoreexceeds3fromthe7thtothe12thdayafteroperationcouldnotbejudgedasarejection.Weshouldpaymoreattentiontothevariationofgraftsopacitysince12daftercornealtransplantation.

  • 标签: CORNEAL TRANSPLANTATION GRAFT SURVIVAL experimental study
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  • 简介:AIM:Topresenttheoutcomeofmodifiedgridlaserphotocoagulation(GLP)indiffusediabeticmacularedema(DDME)ineyeswithoutextrafovealand/orvitreofovealtraction.METHODS:InclusioncriteriafortheretrospectivestudywereDDMEeyesofpatientswithtypeⅡdiabetesmellitusthathad≥4monthsoffollow-upfollowingGLP.Onlyoneeyeperpatientwasanalyzed.Using3-Dspectral-domainopticalcoherencetomography(3-DSDOCT),eyesthathadeitherextrafovealorvitreofovealtraction,orhadbeenpreviouslytreatedbyanintravitrealmedication(s)wereexcluded.TreatedDDMEeyesweredividedinto4groups:A)'Classic'DDMEthatinvolvedthecentralmacula;B)edemadidnotinvolvethemacularcenter;C)eyesassociatedwithcentralepiretinalmembrane(ERM);D)DDMEthatwasassociatedwithmacularcapillarydropout≥2disc-diameter(DD).RESULTS:GLPoutcomein35DDMEeyesafter4-24(mean,13.1±6.9)monthswasasfollows:GroupA)18eyeswith'classic'DDME.Followingoneor2(mean,1.2)GLPtreatments,best-correctedvisualacuity(BCVA)improvedby1-2Snellenlinesin44.4%(8/18)ofeyes,andworsenedby1linein11.1%(2/18).Centralmacularthickness(CMT)improvedby7%-49%(mean,26.6%)in77.8%(14/18)ofeyes.CausesofCMTworsening(n=4)werecommonlyexplainable,predominantly(n=3)associatedwithemergenceofextrafovealtraction,5-9monthspost-GLP.GroupB)GLP(s)inDDMEthatdidnotinvolvethemacularcenter(n=6)resultedinimprovedBCVAby1-2linesin2eyes.However,thecentralmaculabecameinvolvedintheedemaprocessaftertheGLPin3(50%)eyes,associatedwithanemergenceofextrafovealtractioninoneoftheseeyes4monthsfollowingtheGLP.GroupC)GLPfailedinall5eyesassociatedwithcentralERM.GroupD)GLPwasofpartialbenefitin2of6treatedeyeswithmacularcapillarydropout≥2DD.CONCLUSION:EyeswithDDMEthatinvolvedthemacularcenterwerefoundtoachievefavourableoutcomesafterGLP(s)duringmid-termfollow-up,unlesscomplicatedpre-GLPorpost-GLPbyvltreoretinalinterfaceabnormalities,oftenextrafovealtra

  • 标签: extrafoveal TRACTION vitreofoveal TRACTION grid laser
  • 简介:AIM:Toestimatetheprevalenceandriskfactorsforvitreousfloatersinthegeneralpopulation.·METHODS:Anelectronicsurveywasadministeredthroughasmartphoneappaskingvariousdemographicandhealthquestions,includingwhetherusersexperiencefloatersintheirfieldofvision.Multivariatelogisticregressionanalysiswasusedtodetermineriskfactors.·RESULTS:Atotalof603individualscompletedthesurvey,with76%reportingthattheyseefloaters,and33%reportingthatfloaterscausednoticeableimpairmentinvision.Myopeswere3.5timesmorelikely(P=0.0004),andhyperopes4.4timesmorelikely(P=0.0069)toreportmoderatetoseverefloaterscomparedtothosewithnormalvision.Floaterprevalencewasnotsignificantlyaffectedbyrespondentage,race,gender,andeyecolor.·CONCLUSION:Vitreousfloaterswerefoundtobeaverycommonphenomenoninthisnon-clinicalgeneralpopulationsample,andmorelikelytobeimpairinginmyopesandhyperopes.

  • 标签: VITREOUS FLOATERS MYOPIA SURVEY FLOATERS age
  • 简介:Thekeratoprosthesis(KPro;artificialcornea)isaspecialrefractivedevicetoreplacehumancorneabyusingheterogeneousformingmaterialsfortheimplantationintothedamagedeyesinordertoobtainacertainvision.Themainproblemsofartificialcorneaarethebiocompatibilityandstabilityofthetissueparticularlyinpenetratingkeratoplasty.Thecurrentstudiesoftissue-engineeredscaffoldmaterialsthroughcomprisingcompositesofnaturalandsyntheticbiopolymerstogetherhavedevelopedanewwaytoartificialcornea.Althoughawideagreementthatthelong-termstabilityofthesedeviceswouldbegreatlyimprovedbythepresenceofcorneacells,modificationofkeratoprosthesistosupportcorneacellsremainselusive.Mostofthestudiesoncornealsubstratematerialsandsurfacemodificationofcompositeshavetriedtoimprovethegrowthandbiocompatibilityofcorneacellswhichcannotonlyreducethestimulusofheterogeneousmaterials,butalsomoreimportantlycontinuousandstablecorneacellscanpreventthedestructionofcollagenase.Thenecrosisofstromaandspontaneousextrusionofthedevice,allowformaintenanceofaprecornealtearlayer,andplaytheroleofensuringagoodopticalsurfaceandresistingbacterialinfection.Asaresult,improvementincornealcellshasbeenthemainaimofseveralrecentinvestigations;someefforthasfocusedonbiomaterialforitswellbiologicalpropertiessuchaspromotingthegrowthofcorneacells.Thepurposeofthisreviewistosummarythegrowthstatusofthecornealcellsaftertheimplantationofseveralartificialcorneas.

  • 标签: artificial CORNEA KERATOPROSTHESIS tissue-engineered SCAFFOLD CORNEAL
  • 简介:AIM:Toinvestigatetheexpressionofdendriticcell-associatedC-typelectin-1(dectin-1)attheearlyperiodofAspergillusfumigatusinfectioninrat’scornealepithelium.·METHODS:Atotalof72Wistarratswererandomlydividedintothreegroups:A,BandC.Therighteyeswerechosenasexperimentaleyes.GroupAwascontrolgroup.RatsingroupBwerenotinoculatedwithAspergillusfumigatus.GroupCwastakenasAspergillusfumigatuskeratitismodel.RatsingroupBandC(sixfromeachgroup)wereexecutedrandomlyat4,8,16and24hoursafterexperimentalmodelbeingestablishedtoassesstheexpressionofdectin-1mRNAthroughreal-timePCR.AnothersixratsingroupBandCwereexecutedrandomlyat24hourstoassesstheexpressionofdectin-1proteinthroughimmunohistochemistry.·RESULTS:Theresultsofreal-timePCRindicatedthatdectin-1mRNAexpressionwaslowincornealepitheliumofnormalrats’.Therewasnosignificantlydifferenceofdectin-1mRNAexpressioningroupAandB(P>0.05).TheexpressionofAspergillusfumigatusinfectedcornealepitheliumincreasedgraduallyafter8hoursingroupC.ThesynchronousexpressionofgroupAandChadsignificantdifference(P<0.01).Immunohistochemistydiscoveredthatdectin-1receptorexistedinnormalrat’scornealepithelium.Dectin-1proteinincreasedafter24hoursingroupC.TherewasasignificantdifferenceofsynchronousexpressioningroupBandC(P<0.01).·CONCLUSION:Dectin-1existsinrat’scornealepitheliumanditsexpressionsignificantlyincreasesattheearlyperiodofAspergillusfumigatusinfection.Dectin-1isapatternrecognitionreceptorthatexpressesincornealepitheliumandinvolvesinimmuneresponsetoAspergillusfungalkeratitis.

  • 标签: KERATITIS ASPERGILLUS FUMIGATUS DECTIN-1 rat
  • 简介:AIM:Toinvestigatethediffusioncharacteristicsofwaterofopticnerveandopticradiationinhealthyadultsanditsrelatedfactorsbydiffusiontensorimaging(DTI)at3T.METHODS:Atotalof107healthyvolunteersperformedheadconventionalMRIandbilateralopticnerveandopticradiationDTI.TheprimarydataofDTIwasprocessedbypost-processingsoftwareofDTIstudio2.3,obtainingfractionalanisotropyvalue,meandiffusivityvalue,principalenginevalue,orthogonalenginevaluebymeasuring,andanalyzedbytheSPSS13.0statisticalsoftware.RESULTS:Thebilateralopticnerveandopticradiationfiberspresentedgreencolorindirectionalencodedcolor(DEC)mapsandpresentedhighsignalinfractionalanisotropy(FA)maps.TheFAvalueoftheleftopticnervewas0.598±0.069andtherightwas0.593±0.065;themeandiffusivity(MD)valueoftheleftopticnervewas(1.324±0.349)×10-3mm2/sandtherightwas(1.312±0.350)x10-3mm2/s;theprincipalenginevalue(λ?)oftheleftopticnervewas(2.297±0.522)×10-4mm2/sandtherightwas(2.277±0.526)×10-3mm2/s;theorthogonalenginevalue(λ⊥)oftheleftopticnervewas(0.838±0.285)×10-3mm2/sandtherightwas(0.830±0.280)×10-3mm2/s;theFAvalueoftheleftopticradiationwas0.636±0.057andtherightwas0.628±0.056;themeandiffusivity(MD)valueoftheleftopticradiationwas(0.907±0.103)×10-3mm2/sandtherightwas(0.889±0.125)×10-3mm2/s;theprincipaleigenvalue(λⅡ)oftheleftopticradiationwas(1.655±0.210)×10-3mm2/sandtherightwas(1.614±0.171)×10-3mn2/s;theorthogonalenginvalue(λ⊥)oftheleftopticradiationwas(0.531±0.103)×10-3mm2/sandtherightwas(0.524±0.152)×10-3m

  • 标签: magnetic resonance IMAGING diffusion TENSOR IMAGING
  • 简介:填完志愿之后,我又一次,也可能是最后一次伫立在留下了我甜蜜与辛酸教室门前。一种从未体验过空旷和寂寥充斥着眼前这个熟悉而又陌生空间。算起来,高三这一年除了吃饭睡觉和为数寥寥假目,我几乎所有的时光都是在这里度过

  • 标签: 中学生 语文学习 阅读知识 课外阅读
  • 简介:又是一年高考季,志愿填报马上就会成为同学们继高考之后进入大学第二道关口,需要好好把握。现今志愿填报渐渐成为一个技术活,高校排行榜、学科评估排行榜、学生成绩排名估算、高校分数线预测……给了考生和家长不少参考方向,如何确定大学、专业,如何使被录取可能性达到最大是大家最关心问题。

  • 标签: 学生成绩 参考方向 排行榜 高考 大学 高校
  • 简介:孩子,我希望你自始至终都是一个理想主义者。你可以是农民,可以是工程师,可以是演员,可以是流浪汉,但你必须是个理想主义者。

  • 标签: 孩子 理想主义者 工程师 流浪汉
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  • 简介:我现在越来越喜欢使用类比这种思考方式,也越来越喜欢采用比喻说法。我频繁使用上帝这个词,并不意味着我相信一个有人格上帝,一个可以与人沟通神。我只是采用了“上帝”这个比喻性、拟人说法。当然我也可以辩称,我所说上帝是爱因斯坦或者斯宾诺莎上帝,就是自然(规律)本身。

  • 标签: 人造 爱因斯坦 意味着 比喻
  • 简介:今年12月26日,是伟大领袖毛泽东主席诞生120周年纪念日。我和全国人民一样,怀着深深敬意,来缅怀这位中国共产党、中华人民共和国、中国人民解放军缔造者!毛主席为中国革命和建设所作出巨大贡献,他丰功伟绩,永远铭记在中国人民心中,世代相传,我们永远怀念毛泽东主席。我是一个从旧社会过来湘剧艺人,解放后在党教育和培养下,成为了新中国第一代文艺工作者,光荣共产党员。

  • 标签: 中华人民共和国 中国人民解放军 中国革命和建设 幸福 中国共产党 文艺工作者
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  • 简介:摘要教学语言是教学最主要工具。在教学过程中,教学诸多因素最终都要通过教学语言这一媒介发挥作用。教师语言组织和表达能力是影响教学效果重要因素,思想政治课教师要巧用语言艺术,收获“魅力”课堂。

  • 标签: 语言艺术思想政治性魅力课堂
  • 简介:“没有人可以阻止已经开始东西,你一定要相信我说的话!”不久前,在“五一”档上映后口碑爆棚一部家庭式美国动画电影——《疯狂原始人》,其结尾这样唱道。

  • 标签: 《疯狂原始人》 动画电影 家庭式