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简介：探索临床的特征和风险因素的目的在受不了骨质疏松症相关的破裂以及有效干预的病人重新断裂。从2006年1月的方法到2008年1月，我们的医院里的门诊病人和住院病人是超过50岁并且受不了骨质疏松症相关的破裂的人，为这研究被选择。他们被划分成破裂组并且重新断裂组。重新断裂率被跟随在上面为2，年，11个病人在期间发展了重新断裂，因此在重新断裂组被包括。因此，273个病人，225个第一破裂的盒子，变老(67.7

简介：Objective:Toobservehumanneuronalapoptosissecondarytotraumaticbraininjury,andtoelucidateitsregulativemechanismandthechangeofexpressionofapoptosis-relatedgenes.Methods:Specimensofbrainwerecollectedfromcasesoftraumaticbraininjuryinhumans.Thehistologicalandcellularmorphologywasexaminedbylightandelectronmicroscopy.TheextentofDNAinjurytocorticalneuronswasdetectedbyusingTUNEL.ByinsituhybridisationandimmunohistochemistrythemRNAchangesandproteinexpressionofBcl-2,Bax,p53,andcaspase3p20subunitwereobserved.Results:Apoptoticneuronsappearedfollowingtraumaticbraininjury,peakedat24hoursandlastedfor7days.Innormalbraintissueactivatedcaspase3wasrare,butashorttimeaftertraumaitbecameactivated.Theactivitypeakedat20-28hoursandremainedhigherthannormalfor5-7days.TherewasnoexpressionofBcl-2mRNAandBcl-2proteininnormalbraintissuebut8hoursafterinjurytheirexpressionbecameevidentandthenincreased,peakedat2-3daysandremainedhigherthannormalfor5-7days.TheprimaryexpressionofBax-mRNAandBaxproteinwashighinnormalbraintissue.At20-28hourstheyincreasedandremainedhighfor2-3days;onthe7thdaystheyreturnedtoanormallevel.Innormalbraintissue,p53mRNAandP53wereminimallyexpressed.Increasedexpressionwasdetectedatthe8thhour,anddecreasedat20-28hoursbutstillremainedhigherthannormalonthe5thday.Conclusions:Followingtraumaticinjurytothehumanbrain,apoptoticneuronsappeararoundthefocusoftrauma.ThemRNAandproteinexpressionofBcl-2,Baxandp53andtheactivityofcaspase3enzymeareincreased.

简介：Objective:Toassesstheincidence,typesandriskfactorsofmilitarytraining-relatedinjuriesinrecruitsofChinesePeople'sArmedPoliceForces(CPAPF).Methods:Acohortstudywasmadeontheriskfactorsofinjuriesin805malerecruitsduringthemilitarytrainingfromDecember25,1999toDecember25,2000.Results:Atotalof111recruits(14%)experiencedoneormoreinjuries,andthecumulativeincidencewas16.1injuries,andthecumulativeincidencewas16.1inujriesper100soldiersinayear.And77.7%oftheinjuriesbelongedtooveruseinjuriesoftheskeletalandmuscularsystems,themostcommontypeofwhichwasstressfractures.Mostinjuriesoccurredinthe3rdmonthoftraining.Univariateanalysisandlogisticregressionanalysisofpossibleriskfactorsforoveruseinjurieswerecarriedout,andanumberofriskfactorswereidentified:historyofagriculturallabor,historyoflowerlimbinjury,flatfootandlessrunningexercisebeforeentryintothearmy.Butasuitablebodymassindex(BMI)wasaprotectivefactor.Examinationofage,bodyheight,smoking,bodyflexibilityandfrequencyof2-milerunningrevealednosignificantassociationwiththeinjuries.Conclusions:Historyofagriculturallabor,historyoflowerlimbinjury,flatfoot,lessrunningexercisebeforeentryintothearmyandlowerBMIwereriskfactorsoftheoveruseinjuries.Inordertodecreasetheincidenceofoveruseinjuries,theyoungpeoplewithgoodphysicalabilityandshapelybodytypeshouldbeselectedduringconscription.Duringthetraining,nutritionshouldbeimprovedsoastodecreasetheincidenceofinjuries.