简介：Itisproposedthatsomepossiblemacroseismicepicenterscanbedeterminedquicklyfromtherelationshipthatthemicroseismicepicenterslocatedbyinstrumentsbearwithfaults.Basedontheseso-calledmacroseismicepicenters,wecanmakefastseismichazardestimationafterashockbyuseoftheempiricaldistributionmodelofseismicintensity.Incomparisonwiththemethodthatusesthemicroseismicepicentersdirectly,thisapproachcanincreasetheprecisionoffastseismichazardestimation.Statisticalanalysisof133mainearthquakesinChinawasmade.Theresultshowsthatthedeviationdistancebetweenthemicroseismicepicenterandmacroseismicepicenterfallswithintherangeof35kmfor88%earthquakesofthetotalandwithintherangeof35to75kmfortheremainingones.Then,wecantaketheareathathasthemicroseismicepicenterasitscenterandis35kminradiusastheareaforemphaticanalysis,andtaketheareawithin75kmaroundthemicroseismicepicenterastheareaforgeneralanalysis.Therelationbetweenthe66earthquakecasesontheN-SSeismicBeltinChinaandthespatialdistributioncharacteristicsoffaultsandtheresultsoffocalmechanismsolutionwereanalyzedindetail.Weknowfromtheanalysisthattheerrorofinstrumentalepicenterdeterminationisnottheonlyfactorthatgiveseffectstothedeviationofthemacroseismicepicenter.Inadditiontoit,thefaultsize,faultdistribution,faultactivity,faultintersectiontypes,earthquakemagnitude,etc.arealsomainaffectingfactors.Bysortingout,processingandanalyzingtheseaffectingfactors,theprincipleandproceduresforquicklydeterminingthepossiblepositionofthemacroseismicepicenterweresetup.Takingtheseasabasisandestablishinganationwidedatabaseoffaultsthatcontainsrelevantfactors,itispossibletoapplythismethodinpracticalfastestimationofseismichazard.

简介：Thereductionadsorptionofsilverdiamminonitrateondifferentkindsofactivatedcarbonfibers(ACF)hasbeenstudiedinthispaper.Theeffectofdifferentparameters,includingadsorptiontemperature,concentrationsofactivationagents,andactivationtimeonthesilveradsorptioncapacitiesofactivatedcarbonfibershasbeeninvestigatedTheresultsshowthathighertemperatureinwhichthesilvercomplexinteractswithACF.orhigherconcentrationofactivationagent,willmakehigherreductionadsorptioncapacitiesofACFs.Moreover,ACFsactivatedwithphosphoricacidhavehigherreductioncapacitiesthanthoseactivatedwithzincchlorideorsteam.

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简介：ObjectiveToexploretherelationshipbetweensuddensensorineuralhearingloss(SSNHL)andvascularriskfactors(includingserumlipidsanduricacid).MethodThisisaretrospectiveanalysisof100casesofSSNHLseenattheDrumTowerHospital,NanjingMedicalUniversity,betweenJan.2007andApr.2008。Patienthistory,bloodtestresultsandimagingscanswereanalyzed.Levelsoftriglyceride(TG),cholesterols(CHO),highdensitylipoprotein-cholesterol(HDL-CH),lowdensitylipoprotein-cholesterol(LDL-CH),apolipoproteinAI(ApoAI),apolipoproteinB(ApoB)anduricacid(UA)fromthesepatientswerecomparedwithacontrolgroupof56patientstreatedforvocalcordpolypsornasalseptumdeviationduringthesameperiod.Patientswithhypertension,diabetes,heart,brain,liverorkidneydisordersareexcludedfromthepresentinvestigation.ResultsHDLCHlevelwashigherandUAlevellowerinthestudygroupthanthecontrolgroup(P<0.05).HDL-CHandUAshowednosignificantdifferencesamongdifferentage-groups(P>0.05).TherewerenosignificantdifferencesinthelevelsofTG,CHO,LDL-CH,ApoAIandApoB(P>0.05).ConclusionThesedataindicatethatmetabolicdisturbancesofserumlipidsand/oruricacidmaybepotentialriskfactorsforSSNHL

简介：BasedontheinvestigationinAnjiCountyofZhejiangProvinceandBa'nanDistrictofChongqing,thispaperanalyzedthecharacteristicsofforestmanagementbehaviorsofforestfarmersinChinaandtheimpactfactorsforforestmanagementincome,andthencameupwithsomepolicyrecommendationstoincreasetheforestmanagementincomeofforestfarmers.ItarguedthatthefactorstoimpactonforestmanagementincomeofforestfarmersinChinaincludethechoiceofforestproductstype,theelementsinfo...

简介：AbstractAlzheimer disease (AD) is the most common type of dementia characterized by the progressive cognitive and social decline. Clinical drug targets have heavily focused on the amyloid hypothesis, with amyloid beta (Aβ), and tau proteins as key pathophysiologic markers of AD. However, no effective treatment has been developed so far, which prompts researchers to focus on other aspects of AD beyond Aβ, and tau proteins. Additionally, there is a mounting epidemiologic evidence that various environmental factors influence the development of dementia and that dementia etiology is likely heterogenous. In the past decades, new risk factors or potential etiologies have been widely studied. Here, we review several novel epidemiologic and clinical research developments that focus on sleep, hypoxia, diet, gut microbiota, and hearing impairment and their links to AD published in recent years. At the frontiers of AD research, these findings and updates could be worthy of further attention.

简介：AbstractBackground:Keloids are benign fibrous growths that are caused by excessive tissue build-up. Severe keloids exert more significant effects on patients’ quality of life than do mild keloids. We aimed to identify factors associated with the progression from mild keloids to severe keloids, as distinct from those associated with the formation of keloids.Methods:In this retrospective case-control study, 251 patients diagnosed with keloids at West China Hospital between November 2018 and April 2021 were grouped according to the severity of lesions (mild [n = 162] or severe [n = 89]). We collected their basic characteristics, living habits, incomes, comorbidities, and keloid characteristics from Electronic Medical Records in the hospital and the patients’ interviews. Conditional multivariable regression was performed to identify the independent risk factors for the progression of keloids.Results:Eighty-nine patients (35.5%) were classified as having severe keloids. We found the distribution of severe keloids varied with sex, age, excessive scrubbing of keloids, family income, the comorbidity of rheumatism, disease duration, characteristics of the location, location in sites of high-stretch tension, the severity and frequency of pain, the severity of pruritus, and infection. Multivariable analysis revealed significant associations between severe keloids and infection (odds ratio [OR], 3.55; P = 0.005), excessive scrubbing of keloids (OR, 8.65; P = 0.001), low or middle family income (OR, 13.44; P = 0.021), comorbidity of rheumatism (OR, 18.97; P = 0.021), multiple keloids located at multiple sites (OR, 3.18; P = 0.033), and disease duration >15 years (OR, 2.98; P = 0.046).Conclusion:Doctors should implement more active and thorough measures to minimize the progression of mild keloids in patients who have any of the following risk factors: infection, excessive scrubbing of keloids, low or middle family income, comorbidity of rheumatism, multiple keloids located at multiple sites, and disease duration >15 years.

简介：AbstractBackground:Asthma is a heterogeneous disease with distinct prevalence and manifestation between sexes. This study was to identify sex-specific features of asthma via metabolomic analysis of sphingolipids.Methods:Forty-two asthma patients (27 women and 15 men) admitted to the Peking University Third Hospital from January 2015 to December 2015 were enrolled. Peripheral venous blood was collected for metabolomic analysis by targeted liquid chromatography-mass spectrometry. Sex hormones(estradiol, progesterone, testosterone, and androstenedione) and multiple inflammatory factors (periostin, leptin, IgE, IL-4, IL-5, IL-10, IL-13, IL-17A, and IFN-γ) were also assessed. The eosinophil percentage in induced sputum was also detected. All these data were applied to comparative analysis between sexes.Results:Testosterone was negatively related to periostin (ρ = -0.420, P = 0.009) and IL-5 (ρ = -0.540, P = 0.012), while estradiol was positively related to the blood eosinophil percentage (ρ = 0.384, P = 0.025). Among the eighteen species of sphingolipids detected in the 42 patients, five ceramide (Cer) species (Cer16:0, Cer:20:0, Cer22:0, Cer24:0, and Cer26:0) and one sphingomyelin (SM) species (SM38:0) were significantly higher in male than in female patients. Further investigation found that the correlation between Cer20:0 and IL-5 was positive in males (ρ = 0.943, P = 0.005) but negative in females (ρ = -0.561, P = 0.030).Conclusions:Testosterone was negatively correlated with eosinophil inflammatory factors, but estradiol was positively correlated. Male asthma patients had higher ceramide and sphingomyelin levels than female patients. Different sexes had opposite correlations with ceramide and IL-5, respectively, suggesting that therapeutic strategies targeting ceramide should be different between sexes.

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简介：Pulsatilebloodflowsincurvedatheroscleroticarteriesarestudiedbycom-putersimulations.Computationsarecarriedoutwithvariousvaluesofphysiologicalparameterstoexaminetheeffectsofflowparametersonthedisturbedflowpatternsdownstreamofacurvedarterywithastenosisattheinnerwall.Thenumericalre-suitsindicateastrongdependenceofflowpatternonthebloodviscosityandinletflowrate,whiletheinfluenceoftheinletflowprofiletotheflowpattemindownstreamisnegligible.

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简介：男富饶上的精索静脉曲张修理的效果仍然保持争论。它将对有用决定了哪个人将从精索静脉曲张修理有益于大多数，并且在那些个人指向修理努力。为精索静脉曲张修理的预示的因素上的文学的详细评论用PubMedNLM数据库被执行。我们发现postvaricocelectomy精液参数的最好的预言者是外科手术前的精液参数。在精液参数的最大的改进与更大的精索静脉曲张在人被发现。当有争吵，更高的睾丸激素，更年轻的年龄和更大的睾丸尺寸时，在一些，研究在精液参数postvaricocelectomy为改进预言。一张诺模图被开发了基于外科手术前的精液参数，精索静脉曲张等级和这个人(www.fertilitytreatmentresults.com)的年龄预言postvaricocelectomy精液参数。有限数据一致地与更高的基线DNA破碎率在人处于DNA破碎率表明最大的改进。关于繁殖结果，更高的基线精子密度一致地为自然怀孕或帮助繁殖技术(艺术)怀孕率预言。另外，精索静脉曲张修理确实似乎为艺术的更侵略的形式减少需要。在结论，我们现在能开始使用象预言跟随varicocelectomy的修理以后的精液质量和富饶潜力的基线精液质量，精索静脉曲张等级和耐心的年龄那样的特定的参数。

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简介：到hamstring的BackgroundInjuries在职业cricketers是相对普通的(因为他们在许多队运动)并且自从2006.MethodsThis学习分析了发生，在板球的T20时代(20-over比赛的介绍)在发生增加了喻摧毁在各种各样的精英男性比赛的损害在一个20年的时期上打字(到2014-2015季节的1995-1996)。风险因素为喻摧毁紧张用逻辑回归分析technique.ResultsThere是的multivariate被估计276比赛时间损失喻摧毁在州或国家的运动员水平，170发生在40,145运动员火柴之一设置的澳大利亚人在一个20年的时期上记录的损害。比赛发作率的全面的率是22.5喻摧毁损害每1000队天。快保龄发作损害每1000队天是以10.9损害的率的最高的子范畴，尽管打的发作损害在50-over(一天)是特别地普通的国际比赛。在逻辑回归分析的重要风险因素，除了喻摧毁损害历史，正在是快bowler亲戚风险(RR)2.5(95%信心间隔(CI)：1.3-4.5)并且在澳大利亚RR2.3玩一场比赛(95%CI：1.3-3.9).ConclusionFastbowlers承受更多喻摧毁损害比在板球的另外的玩的角色，特别地在头等(多天)上板球。Batsmen是更可能的变得在50-over(一天)受伤了板球。在澳大利亚玩(与海外地点相比)导致增加的风险喻摧毁损害。

简介：Withthearrivaloftheeraofpersonalautoconsumption,residentsareenjoyingtheconvenienceoftravel;however,problemssuchasenvironmentalprotection,transportation,purchasingrestrictionareplaguingconsumersatthesametime.Asaneffectivealternativetoconventionalvehicle,electricvehicleinrecentyearshasbeenwidelyconcernedduetoitscharacteristicsofenergysavingandenvironmentalprotection.ToidentifythekeyinfluentialfactorsinthedevelopmentofEVindustryinChinaisconducivetoformulatingreasonableindustrialdevelopmentstrategyandmeetingmarketdemandofconsumers.Inthispaper,thekeyfactorsinthedevelopmentofEVindustryareobtainedbyanalyzingBaiduIndexineachtimeperiod.