简介：U-shapedmicro-nanochannelscangeneratesignificantflowdisturbanceaswellaslocallyamplifiedelectricfield,whichgivesitselfpotentialtobemicrofluidicmixers,electrokineticpumps,andevencelllysisprocess.NumericalsimulationisutilizedinthisworktostudythehiddencharacteristicsoftheU-shapedmicro-nanochannelsystem,andtheeffectsofkeycontrollingparameters(theexternalvoltageandpressure)onthedeviceoutputmetrics(current,maximumvaluesofelectricfield,shearstressandflowvelocity)wereevaluated.Alargeportionofcurrentflowingthroughthewholesystemgoesthroughthenanochannels,ratherthanthemiddlepartofthemicrochannel,withitsvalueincreasinglinearlywiththeincreaseofvoltage.Duetothelocaliondepletionnearmicro-nanofluidicjunction,significantlyenhancedelectricfield(asmuchas15foldatV=1VandP0=0)aswellasstrongshearstress(leadingtoelectrokineticflow)isgenerated.Withincreasingexternalpressure,bothelectricfieldandshearstresscanbeincreasedinitially(duetoshorteningofdepletionregionlength),butaresuppressedeventuallyathigherpressureduetothedestructionofiondepletionlayer.Insightsgainedfromthisstudycouldbeusefulfordesigningnonlinearelectrokineticpumpsandothersystems.

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简介：Livercancer,primarilyhepatocellularcarcinoma(HCC),isamajorcauseofcancer-relateddeathworldwide.HCCisasuitablemodelofinflammation-inducedcancerbecausemorethan90%ofHCCcasesarecausedbyliverdamageandchronicinflammation.Severalinflammatoryresponsepathways,suchasNF-κBandJAK/STAT3signalingpathways,playrolesinthecrosstalkbetweeninflammationandHCC.MicroRNAs(miRNAs)areevolutionarilyconserved,shortendogenous,non-codingsingle-strandedRNAsthatareinvolvedinvariousbiologicalandpathologicalprocessesbyregulatinggeneexpressionandproteintranslation.EvidenceshowedthatmiRNAsplayapivotalroleinhepatitisvirusinfectionandserveaspromotersorinhibitorsofinflammatoryresponse.AberrantmiRNAwasobservedduringliverinflammationandHCC.ManydysregulatedmiRNAsmodulatetheinitiationandprogressionofinflammation-inducedHCC.ThisreviewsummarizestheroleandfunctionsofmiRNAsininflammation-associatedHCC,aswellasthedesignedtherapeuticstargetingmiRNAstotreatliverinflammationandHCC.

简介：目标结构的机械颤动将调制雷达backscattering的阶段函数，并且将从目标导致返回的信号的频率调整。它产生目标身体Doppler频率的乐队转移的一个方面，它对目标识别有用。基于这，micro-Doppler原子宝库为目标识别被造，并且四种普通分类器独立被使用执行分类识别。模拟试验性的结果证明这个方法让高识别超过90%评价。

简介：Thepropertyofsiliconmicro-capacitiveaccelerometerisanalyzedanddiscussedbyestablishingthemodelofthesensor,tolayabasisforoptimizationdesignofsensorsystemstructure.Discussedissuesincludethestaticmodelinganddynamicbehaviorofthetwocommnlyusedstructures,i.e.,double-cantileversupportedandfour-beamsupportedstructures,andalsothemeasurementrangeofthesedevices.

简介：Theload-bearingcapacitiesofduclilecompositematerialsandstructuresarestudiedbymeansofacombinedmicro/macromechanicsapproach.Firstly,onthemicroscopicscale,theaimistogetthemacroscopicstrengthdomainsbymeansofthehomogenizationtheoryofmicromechanics.Arepresentativevolumeelement(RVE)isselectedtoreflectthemicrostructuresofthecompositematerials.Byintroducingthehomogenizationtheoryintothekinematiclimittheoremofplasticlimitanalysis,anoptimizationformaltodirectlycalculatethelimitloadsoftheRVEisobtained.Andthemacroscopicyieldcriterioncanbedeter-minedaccordingtotherelationbetweenmacroscopicandmicroscopicfields.Secondly,onthemacroscopicscale,byintroducingtheHill’syieldcriterionintothekinematiclimittheorem,thelimitloadsoforthotropicstructuressuchasunidirectionalfiber-reinforcedcompositestructuresareworkedout.Thefiniteelementmodelingofthekinematiclimitanalysisisdeducedintoanonlinearmathematicalprogrammingwithequality-constraintconditionsthatcanbesolvedbymeansofadirectiterativealgorithm.Finally,someexamplesareillustratedtoshowtheapplicationofthepresentapproach.

简介：Asiliconeacrylatemicro-emulsionofmultipolymerwaspreparedbyseedemulsionpolymerization.Theeffectsofpolymerizationprocess,emulsifierrateandamount,initiatorrateandamount,polymerizationtemperature,functionalmonomers,titrationtimeonperformancesofemulsionhavebeendiscussedindetail.

简介：以便调查设计方法因为一台微离心的压缩机，它是一台极端微煤气的汽轮机的最重要的部件，有2-dimensional片的离心的impeller的二种类型被设计，生产并且测试。这些impellers与对方一起在南方的飞机上有中心的不同形状。而且，impeller的这些类型为5被成为次和期末考试的6次尺寸与4mm的外部直径指向离心的impeller以便为impellers估计类似。在impellers的表演特征之中的比较在表演和压缩机的类似上揭示了南方的配置的影响。

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简介：AbstractThe human gastrointestinal tract accommodates an entire micro-environment for divergent physiologic processes, the dysbiosis of this micro-ecology has a strong inter-action with the pathogenesis of inflammatory bowel disease (IBD). In the past few years, with the advances in the understanding of microbiome, its metabolites and further application of next generation sequencing, analysis of dynamic alteration of gut micro-environment was realized, which provides numerous information beyond simple microbiota structure or metabolites differences under chronic colitis status. The subsequent intervention strategies targeting the modulation of intestinal micro-environment have been explored as a potential therapy. In this review, we will summarize the recent knowledge about multi-dimensional dysbiosis, the inter-action between fungus and bacteria under inflamed mucosa, and the clinical application of probiotics and fecal microbiota transplantation as a promising therapeutic approach in IBD.

简介：Fabricationofmicrogratingsusingafemtosecondlaserexposuresystemisexperimentallyinvestigatedfortheelectronmoirémethod.Microholesandlinesarefirstlyetchedforparameterstudy.Gratingprofileistheoreticallyoptimizedtoformhighqualitymoirépatterns.Forademonstration,aparallelgratingisfabricatedonaspecimenofquartzglass.Theminimumlinewidthandthedistancebetweentwoadjacentlinesarebothsettobe1μm,andthefrequencyofgratingis500lines/mm.Theexperimentalresultsindicatethatthequalityofgratingsisgoodandtherelativeerrorofthegratingspitchisabout1.5%.Basedonmoirémethod,scanningelectronmicroscope(SEM)moirépatternsareobservedclearly,whichmanifeststhatgratingsfabricatedwiththefemtosecondlaserexposureissuitableformicroscaledeformationmeasurement.

简介：ＴＨＥＭＩＣＲＯ－ＦＥＡＴＵＲＥＳＯＦＨＥＡＶＹＲＡＩＮＯＶＥＲＧＵＡＮＧＺＨＯＵＩＮＦＬＯＯＤＳＳＥＡＳＯＮ￥ＤｅｎｇＸｕｅｊｉａｏ，ＨｕａｎｇＨａｏｈｕｉａｎｄＷｕＤｕｉ邓雪娇，黄浩辉，吴兑（ＧｕａｎｇｚｈｏｕｉｎｓｔｉｔｕｔｅｏｆＴｒｏｐｉｃａ...

简介：※流明帮手2000流明帮手利用Windows操作系统提供您一个熟悉且容易使用的图形使用者接口。提供CAD接口一房间、对象(包括隔屏、桌子和椅子）与照明器具皆可使用鼠标作插入、移动、复制与删除之处理。三维立体检视画面提供您以卓越的视觉与设计操控能力，流明帮手循序渐进提示

简介：1IntroductionEarlyattemptstocreateasoundabsorberwhichwouldfunctionwithouttheinvolvementofanyfibrousorporousdampingmaterialgofarbacktoK.A.Veliszhanina,S.N.RschevkinandothersaswasoutlinedinRef.[1].30yearsago,D.Y.MAA[2]wasfirstinproposingapracticabledesignconceptandcalculationmodelforMicro-PerforatedAbsorber(MPA)prototypeswhichstillformsthebasisforvariousapplications.Duringthepast12yearstheFraunhoferIBP

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简介：以便减少磨擦力量并且在低速度消除一个技工系统的粘住滑倒现象，一个方法基于超声的微开车技术被建议改变摩擦特征。顺时针方向激动并且在超声的致动器的二个纵的夹钳门栓的震荡器上驾驶点的逆时针方向的显微镜的椭圆的运动将产生超声的润滑油行动；而且，磨擦能被调整震荡器的颤动的振幅活跃地控制。为磨擦控制的试验性的安装用航空的指南，力量传感器和一低速度时刻被设计motor.Fuzzy控制理论被使用进这个系统。实验显示磨擦力量大部分被减少了，试验性的系统的运动是稳定的。当超声的致动器和负担is3.8kg和马达的全部的团正在开车时，磨擦系数仅仅是大约0.0053速度是0.5mm/s。

简介：维的计量学的精确上的要求在半导体生产的区域是特别紧的。这在面具和硅晶片和他们的相应参考计量学上特别地为最小的结构的线宽的测量和控制成立。在这篇论文，我们将描述物理模型和在PTB为光罩线宽计量学被开发的参考书乐器学。它将被显示出，不同方法的结果怎么能被用于比较分析。这些方法的应用程序将根据最新发达的光罩线宽标准作为模范地被演示。

简介：为为快速的扫描激光横梁的pulsing激光横梁和Galvano扫描仪的Q开关被改编在水微滴操作微稳固的粒子。由激光横梁照耀由一个钇铝柘榴石激光系统，导致的流动，和粒子的导致的运动在微米大小的直径套住好粒子被讨论。粒子旋转被使用各向异性的微目标观察，并且而且旋转的率与顺时针方向方向是22r/min。一只盖子杯子的碎片在水微滴被混合，并且他们的尺寸和形状是不平的。没有由Galvano扫描仪扫描的那个非范围的旋转也在水里被观察。

简介：Themolluskshellmobilizescalciumfromenvironmentforskeletalmineralization.Thisoccursthroughsynthesizingsolidsinsolutioninthepresenceoforganicmoleculesofspecificinteriorregionsoftheconchshell.TheultrastructureandmicrohardnessoftheHemifusustubaconchshelllivingintheHuang/Boseaareaareinvestigatedinthepaper.Itisshownthatthecompositionandmicrostructureofthemolluskshellvaryindifferentpositions.Theprodissoconchshellconsistsonlyofaragonitewiththecrossed-lamellarmicrostructure.WhilethespiralshellandthebodyshelloftheHemifusustubaconchshellarecomposedofonecalcitelayerandseveralaragonitelayers.Thecalcitelayerconsistsofcylindricalgrains,butthearagonitelayersarecrossed-lamellarultrastructureatthreesizescales.Theminimumstructuresize(thethird-orderlamella)isatabout20nm-80nm.Themarginofshellapertureisonlycomposedofcalcitewithcylindricalgrains.ThisnaturaloptimizationoftheshellmicrostructureisintimatelyduetothegrowthoftheOrganicmatrix.Atdifferentpositionsthemicrohardnessofmolluscshellisdifferentduetodifferentcrystalstructuresandcrystalarrangements.Thegrowthprocessofshellsallowsaconstantrenewalofthematerial,thusenablingtheirfunctionaladaptationtoexternalenvironments.