简介：Basedonthegivenreactionconditionandmedium,thegrowthofmicro-andnanocrystalscanbedividedintofourtypes,growthinsolutionatnormalpressure,hydrothermalgrowth,solvothermalgrowth,andmolten-saltgrowth.Whenthewaterororganicsolventasthereactionmedium,surfactant,suchassodiumdodecylbenzenesulfonate,canbeaddedtoregulatethe

简介：AIM:ToscreenmicroRNAs（miRNAs）andsetuptargetmiRNAsinpterygium.METHODS:PrimaryfibroblastswereisolatedfrompterygiumandTenon’scapsuleandcultured.ImmunocytochemicalanalysisandWesternblottingwereperformedtoconfirmthecultureoffibroblasts.Inall,1733miRNAswerescreenedinthefirststepbyusingGeneChip?miRNA3.0Array.SpecificmiRNAsinvolvedinthepathogenesisofpterygiumweresubsequentlydeterminedusingthefollowingcriteria:1)highreproducibilityinarepetitivetest;2)baselogvalueof>7.0forbothcontrolandpterygialfibroblasts;and3)logratioof>1.0betweenpterygialfibroblastsandcontrolfibroblasts.RESULTS:Primaryscreeningshowedthat887/1733miRNAswereup-regulatedand846/1733miRNAsweredown-regulatedinpterygialfibroblastscomparedwiththoseincontrolfibroblasts.Ofthe1733miRNAsscreened,4miRNAs,namely,miRNA-143a-3p,miRNA-181a-2-3p,miRNA-377-5pandmiRNA-411a-5p,mettheabove-mentionedcriteria.Primaryscreeningshowedthatthese4miRNAswereup-regulatedinpterygialfibroblastscomparedwithcontrolfibroblastsandthatmiRNA-143a-3phadthehighestmeanratiocomparedwiththemiRNAsincontrolfibroblasts.CONCLUSION:miRNA-143a-3p,miRNA-181a-2-3p,miRNA-377-5pandmiRNA-411a-5pareup-regulatedinpterygialfibroblastscomparedwithcontrolfibroblasts,suggestingtheirinvolvementinthepathogenesisofpterygium.

简介：WereportamonolithicTm:YLFmicrolaserinthisLetter.Inordertoimprovetherelaxationoscillationofthelaser,bothendsofthecrystalarecoated,makingtheTm:YLFcrystalitselfaresonantcavity.Themicrolaserispumpedbya792nmlaserdiodeoperatedinthecontinuouswave(CW)mode.Weobtainmaximumoutputpowersof7.78and10.4Watthetotalincidentpowerof43.6Wwithfocuslensesof37.5and40mm,respectively,correspondingtotheslopeefficienciesof25.6%and40.0%andtheoptical–opticalconversionefficienciesof17.8%and23.8%.Itisclearthattheamplitudeoftherelaxationoscillationissmallerandthebeamqualityisbetterwiththefocuslengthof37.5mm;however,thelaserwiththefocuslengthof40mmproducesahigheroutputpowerandamorestablewavelengthcenteringat1878.44nm.

简介：Inthispaper,wepresentahighspeedautofocussystemformicrosystemapplicationsanddesignalook-up-tablebasedautofocusingalgorithmforapplicationswhenatargetobjectisalwaysvisible,e.g.,manufacturingpartswithalignmentfiducials.Weperformanevaluationof24focusmeasurestoverifythatwhichfocusmeasureisthebestforthelook-up-tablebasedmethod.Fromtheevaluation,wefindthattheChebyshevmoments-basedfocusmeasure(CHEB)isthemostsuitable.Furthermore,wealsodevelopalook-up-tablebasedautofocussystemthatusesCHEBasthefocusmeasure.Intrainingphase,weofflineconstructatablefromtrainingimagesofanobjectthatarecapturedatseverallensdistances.Eachentryoftableconsistsoffocusmeasurecomputedfromimageandlensdistance.Inworkingphase,givenaninputimage,thealgorithmfirstcomputesthefocusmeasureandthenfindsthebestmatchfocusmeasurefromthetableandlooksupthecorrespondinglenspositionformovingitintothein-focusposition.Ouralgorithmcanperformautofocusingwithinonly2stepsoflensmoving.Theexperimentshowsthatthesystemcanperformhighspeedautofocusingofmicroobjects.

简介：Livercancer,primarilyhepatocellularcarcinoma(HCC),isamajorcauseofcancer-relateddeathworldwide.HCCisasuitablemodelofinflammation-inducedcancerbecausemorethan90%ofHCCcasesarecausedbyliverdamageandchronicinflammation.Severalinflammatoryresponsepathways,suchasNF-κBandJAK/STAT3signalingpathways,playrolesinthecrosstalkbetweeninflammationandHCC.MicroRNAs(miRNAs)areevolutionarilyconserved,shortendogenous,non-codingsingle-strandedRNAsthatareinvolvedinvariousbiologicalandpathologicalprocessesbyregulatinggeneexpressionandproteintranslation.EvidenceshowedthatmiRNAsplayapivotalroleinhepatitisvirusinfectionandserveaspromotersorinhibitorsofinflammatoryresponse.AberrantmiRNAwasobservedduringliverinflammationandHCC.ManydysregulatedmiRNAsmodulatetheinitiationandprogressionofinflammation-inducedHCC.ThisreviewsummarizestheroleandfunctionsofmiRNAsininflammation-associatedHCC,aswellasthedesignedtherapeuticstargetingmiRNAstotreatliverinflammationandHCC.

简介：Fabricationofmicrogratingsusingafemtosecondlaserexposuresystemisexperimentallyinvestigatedfortheelectronmoirémethod.Microholesandlinesarefirstlyetchedforparameterstudy.Gratingprofileistheoreticallyoptimizedtoformhighqualitymoirépatterns.Forademonstration,aparallelgratingisfabricatedonaspecimenofquartzglass.Theminimumlinewidthandthedistancebetweentwoadjacentlinesarebothsettobe1μm,andthefrequencyofgratingis500lines/mm.Theexperimentalresultsindicatethatthequalityofgratingsisgoodandtherelativeerrorofthegratingspitchisabout1.5%.Basedonmoirémethod,scanningelectronmicroscope(SEM)moirépatternsareobservedclearly,whichmanifeststhatgratingsfabricatedwiththefemtosecondlaserexposureissuitableformicroscaledeformationmeasurement.

简介：高温度液体被注入微尺寸毛状并且它的轻繁殖行为被调查。我们集中于抽方法的二不同液体。第一个方法能把高温度液体听输入微尺寸由使用一个高压力差别系统毛状。在抽以后，与光搬运人一起连接的单个模式纤维(SMF)基于微波interferometry(OCMI)系统被用来测量不同液体听层次在微尺寸毛状。第二个方法能把房间温度引擎油输入由使用注射泵毛状。当液体被输入时，这个方法能避免空气水泡毛状。

简介：Propagation-basedphase-contrastimagingwassimulatedbasedonparaxialFresnel-Kirchoffdiffractionintegralandsphericalwaveillumination.Underadevelopedmicro-CTsystemparameters,theeffectsoffocal-spotsizeandimaginggeometryonphase-contrastimaginghavebeeninvestigatedusinga2-mm-thicknesspolystyreneedgephantom.Anequivalentmono-energywasusedtosubstitutethepolychromaticspectrumofthemicro-focusX-raysource.Toconsidereffectsoffocal-spotsizeanddetectorresolution,theobtainedphase-contrastimagewithanidealpointsourcewasconvolvedwithsourceintensitydistributionandpointspreadfunctionofdetector.Simulationsshowreasonableinfluencesofthetwoparameterswhichareingoodagreementwithexperimentalresults.

简介：我们在这份报纸在场计划方法的一条柔韧的联机路径，它在否认GPS、撒布障碍的环境安全地允许一只微旋转飞机雄蜂到苍蝇与限制了机载的计算力量。途径基于到二个点边界价值问题(TPBVP)的一张高效地管理的格子地图和一个靠近形式的答案。而TPBVP的答案产生光滑的轨道，格子地图帮助轨道评估。最后，交换算法的一条最高层的轨道被利用最小化计算费用。建议途径的优点包括它计算资源的保存，轨道产生的坚韧性和对未知环境的反应的活泼。结果在实际雄蜂平台上被认识到并且成功地在真实飞行测试示威了。飞行测试的录像能被发现在：http://uav.ece.nus.edu.sg/robust-online-path-planning-Lai2015.html。

简介：

简介：Inthispaper,weproposeaninstantaneousphase-steppingmethodfordeterminingphasedistributionofinterferencefringesutilizingacamerathatisequippedwithamicro-polarizerarrayonthesensorplane.AnopticalsetupofpolarizationinterferometryusingaMach–Zehnderinterferometerwithtwopolarizersisconstructed.Lightemergingfromtheinterferometerisrecordedusingacamerathathasamicro-polarizerarray.Thismicro-polarizerarrayhasfourdifferentopticalaxes.Thatis,animageobtainedbythecameracontainsfourtypesofinformationcorrespondingtofourdifferentopticalaxesofthepolarizer.Thefourimagesseparatedfromtheimagerecordedbythecameraarereconstructedusinggraylevelinterpolation.Subsequently,thedistributionsoftheStokesparametersthatrepresentthestateofpolarizationarecalculatedfromthefourimages.ThephasedistributionoftheinterferencefringepatternproducedbytheMach–ZehnderinterferometeristhenobtainedfromtheseStokesparameters.Theeffectivenessoftheproposedmethodisdemonstratedbymeasuringastaticcarrierpatternandtime-variantfringepatterns.Itisemphasizedthatthismethodisapplicabletotime-variantphenomenabecausemultipleexposuresareunnecessaryforsufficientdataacquisitioninthecompletionofthephaseanalysis.

简介：Aneffectivedesignmethodoffreeformmicrolensarrayispresentedforshapingvariedlaserbeamsintoprescribedrectangularillumination.Thevariableseparationmappingisappliedtodesignconcavefreeformsurfacesforconstructingafreeformlensarray.Severaldedicatedexamplesshowthatthedesignedfreeformopticallensarraycanachieveaprescribedrectangularilluminationpattern,especiallywithoutconsideringtheinitialstatesofincidentlaserbeams.Bothhighcollectionefficiencyandgoodspatialuniformitycanbeavailablesimultaneously.Toleranceanalysisisalsoperformedtodemonstratethatthisopticaldevicecanwellavoidfabricatingdifficultyinactualapplications.

简介：基于Si的多层的结构广泛地在当前的微电子学被使用。在他们的准备期间，一些不同类的剩余应力被导致，导致在接口错配和表面精力和平导致结构失败之间的竞争。这个工作在多层的半导体heterostructure在剩余应力的测量上介绍方法学的研究。扫描电子显微镜学(SEM)，micro-Raman光谱学(太太)，和传播电子显微镜学(TEM)被使用测量多层的结构的几何参数。在拉曼光谱和压力/紧张在上之间的关系[100]并且[110]水晶取向被决定分别地启用表面和剖面图剩余压力分析。基于印射结果的拉曼，沿着多层的heterostructure的深度的剩余应力的分发成功地被获得。

简介：Inthisstudy,etherificationofginkgolideBanddimethylaminoethylchloridehydrochloridewasinvestigatedasamodelreactioninamicro-flowsystem(MFS),providingtheresultingethersinhighyieldwithfewersideeffects.Meanwhile,thisnovelprocessinMFSworkedwellforotherginkgolidesfromGinkgolbilobaandhalides,givingmoderateyields.

简介：Asimplemethodtofabricateone-dimensional(1-D)andtwo-dimensional(2-D)orderedmicro-andnano-scalepatternsisdevelopedbasedontheoriginalmastersfromopticaldiscs,usingnanoimprinttechnologyandsoftstamps.Polydimethylsiloxane(PDMS)wasusedtoreplicatethenegativeimageofthe1-DgratingpatternonthemastersofCD-R,DVD-RandBD-Ropticaldiscs,respectively,andthenthe1-DpatternononeofthePDMSstampswastransferredtoablankpolycarbonate(PC)substratebynanoimprint.The2-DorderedpatternswerefabricatedbythesecondimprintingusinganotherPDMSstamp.Different2-DperiodicpatternswereobtaineddependingonthePDMSstampsandtheanglebetweenthetwotimesofimprints.Thismethodmayprovideawayforthefabricationofcomplex2-Dpatternsusingsimple1-Dmasters.

简介：WecollectedacornsfromselectedQuercusroburandQuercuspetraeamothertreesgrowingatstationswithdifferentdepthstothewatertable.Weproducedpairsofmicro-cuttingsfromthesesingleacorns.Theobtainedpairsofcuttingsrepresentedphenotypesofhighsimilarityaccordingtophotosyntheticparameters.Thesepairsofcuttingswereusedtotesttheplasticityofresponsetocontrastingwaterregimes.Foreachpair,onecuttingwassubmittedtodroughtandtheotherwassubmittedtowaterlogging.Droughtresponsewasrecordedaccordingtogasexchangetraits（stomatalclosureandwateruseefficiency）.TheresponsetowaterloggingwasrecordedaccordingtothecapacitytoformhypertrophiedlenticelsandtomaintaintheCO2assimilationrate.Intermediaryphenotypespresentingbothhighwateruseefficiencyandthecapacitytodevelophypertrophiedlenticelswereexpected.

简介：题目：悬浮等离子体喷涂过程中微纳米颗粒撞击基板的动力学模拟目的：研究微纳米颗粒在流场中的运动和传热特性，确定颗粒绕流的临界尺寸以及微纳米颗粒合适的喷涂距离。创新点：1．建立微纳米颗粒的受力和运动模型；2．推导颗粒粒径和斯托克斯数的关系，确定颗粒绕流的临界尺寸；3．确定适于微纳米颗粒的喷涂距离。方法：1．通过颗粒运动和传热的三维模型，模拟颗粒在等离子体流场中的运动和传热过程；2．对流场采用欧拉法进行求解，对颗粒采用拉格朗日法进行求解；3．动态追踪颗粒的轨迹和空间分布，从而得到颗粒的速度、温度和空间分布。结论：1．布朗力会影响纳米颗粒的分布；现有模型可以很好地模拟微纳米颗粒的行为。2．可以用斯托克斯数和粒径表征微纳米颗粒绕流的临界尺寸；当前工况下，临界粒径约为800nm。3．基板会影响流场结构和颗粒的空间分布；在当前研究中，得出有利于纳米颗粒沉积的喷涂距离约为50mm；对微米颗粒来说，喷涂距离应适当增大。4．微纳米颗粒的空间分布呈现不同的特点；纳米颗粒的分布区间更大，布朗力对纳米颗粒的作用比对微米颗粒更为显著。5．微纳米颗粒的运动和传热过程呈现不同的特点；纳米颗粒的惯性和热容小，因此它们的速度和温度变化更迅速。

简介：Room-temperatureterahertz（THz）detectorsindicateagreatpotentialintheimagingapplicationbecauseoftheirreal-time,compactbulk,andwidespectralbandrespondingcharacteristics.THzdetectorswithdifferentdimensionsbasedonamicro-bridgestructurehavebeendesignedandfabricatedtogetoptimizedmicro-bolometerparametersfromthetestresultsofmembranedeformation.Ananostructuredtitanium（Ti）thinfilmabsorberisintegratedinthemicro-bridgestructureoftheVOxmicro-bolometerbyacombinedprocessofmagnetronsputteringandreactiveionetching（RIE）,anditsimprovementofTHzabsorptionisverifiedbyanopticalcharacteristicsmesurement.Continuous-waveTHzdetectionandimagingaredemonstratedbyusinga2.52THzfarinfraredCO2laseranda320×240vanadiumoxidemicro-bolometerfocalplanearraywithanoptimizedcellstructure.Withthisdetectingsystem,THzimagingofmetalconcealedinawipingclothandanenvelopeisdemonstrated,respectively.

简介：Angularcoloruniformity(ACU)isakeyfactorusedtoevaluatethelightqualityofwhite-lightemittingdiodes(LEDs).Inthisstudy,anoveldoubleremotemicro-patternedphosphorfilm(doubleRMPPfilm)wasusedtoenhancetheACUofaremotephosphor(RP)down-lightlamp.AconventionalRPfilmandremotephosphorfilmwithsinglemicro-patternedfilm(singleRMPPfilm)alsowereexaminedforcomparison.Theangularcorrelatedcolortemperature(CCT)distributionsandtheopticalperformanceofthefilmswereexperimentallymeasured.ThemeasurementresultsshowedthatdoubleRMPPfilmconfigurationexhibitedbettercoloruniformitywithaCCTdeviationofonly441K,comparedwith556KforthesingleRMPPfilmconfigurationand1390KfortheRPfilmconfiguration.AsimulationbasedonFDTDandraytracingcombinedmethodalsoconfirmedtheACUimprovement.Inaddition,comparedwiththeconventionalRPfilm,theluminousefficiencyofsingleanddoubleRMPPfilmconfigurationswasincreasedby6.68%and4.69%,respectively,atadrivingcurrentof350mA.TheenhancementoftheACUandluminousefficiencyareduetothescatteringandmixingeffectofthemicropatternedfilm.Moreover,thedoubleRMPPfilmconfigurationhadbetterCCTstabilityatdifferentcurrentsthantheothertwoconfigurations.TheresultsdemonstratedtheeffectivenessandsuperiorityofdoubleRMPPfilminwhiteLEDapplications.

简介：