简介:AbstractVitiligo, a common skin depigmentation disorder, is the result of complex interactions of genetic, immunological, environmental, and biochemical events. Treatments for vitiligo include drugs, phototherapy, surgical transplantation, and so on. Among them, the efficacy of narrow band-ultraviolet B has been confirmed. By inducing keratinocyte-derived factors and signalings, narrow band-ultraviolet B can trigger and/or promote the mobilization of melanocytes which migrate to lesional epidermis ultimately, leads to the repigmentation of white patches. The mobilization of melanocytes includes stages of activation, migration, proliferation, and differentiation. Elucidating processes that enable the specific mobilization of melanocytes and the signaling pathways and factors involved, will help the development of new drugs and methods for the treatment of vitiligo.
简介:摘要目的探讨UVB高能紫外线照射治疗白癜风的临床效果。方法中波(UVB)高能紫外线照射并结合心理疗法治疗42例白癜风患者。结果经8周治疗,总有效率86%。结论中波(UVB)高能紫外线照射结合针对性的心理疗法对治疗白癜风疗效肯定。
简介:摘要目的分析研究复方甘草酸酐联合窄波紫外线以及抗组胺药联合窄波紫外线针对治疗玫瑰糠疹的治疗效果。方法将2011年10月~2013年5月就诊的120例玫瑰糠疹患者随机分为两组,观察组和对照组各60例,观察组患者使用复方甘草酸酐联合窄波紫外线进行治疗,对照组患者使用抗组胺药联合窄波紫外线进行治疗,比较两组患者的治疗效果。结果通过治疗结果显示,观察组患者的治疗有效率为82.53%,对照组患者的治疗有效率为66.06%,两组患者的治疗有效率比较有明显差异(P<0.05),具有统计学意义。结论复方甘草酸酐联合窄波紫外线进行治疗玫瑰糠疹不但治疗效果显著,而且能够缩短患者的病程,值得在临床科室中广泛推广。
简介:摘要目的观察中药药浴联合NB-UVB治疗银屑病的疗效。方法治疗组598例为用中药浴+NB-UVB,对照组520例采用口服复方氨肽素片,外用达力士软膏治疗,以银屑病皮损面积和严重度指数(PASI)评价疗效;结果治疗组有效率86%,采用中药药浴联合NB-UVB治疗银屑病疗效显著,治愈后不易复发,较单一治疗效果更佳。
简介:摘要目的了解清热凉血中药联合窄谱中波紫外线(NB-UVB)治疗寻常性银屑病的疗效。方法寻常性银屑病血热型患者119例,随机分为联合组(消银合剂+NB-UVB)60例,光疗组(NB-UVB)59例,六周后判定疗效。结果两组疗效差异有统计学意义。结论联合组疗效高于对照组,消银合剂联合NB-UVB治寻常性银屑病具有协同或增效作用。