学科分类
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22 个结果
  • 简介:Inarecentstudy,researcherstookadultfemaleFischerratsandperformedaspinalcordtransectionontheminanattempttostudythegrowthoftransplantedearly-stageneurons.Whensuchearly-stageneuronsweretransplantedintoratssufferingfromparalysis,remarkableaxonalgrowthwasobserved.Theresultwasmanynewrelaycircuitsthatformed,whichsignificantlyimprovedfunction,

  • 标签: 干细胞移植 大鼠 瘫痪 生长早期 研究人员 轴突生长
  • 简介:《AfterEffects影视特效》从课程特色入手,结合教学实践,合理地取舍教学内容,做到理论与实践相结合,采取"问题"式教学诱导学习动机;"举一反三"式引导自主学习;"项目"式驱动学习兴趣,进行创新性教学,解决课程中存在的教学硬件配置落后、学生的能力参差不齐、学生美术基础薄弱等问题,并建立合理的考评机制,从而充分调动学生学习积极性,达到提高学生创新能力和实践能力的目标。

  • 标签: 《After Effects》 课程改革 影视特效 项目教学 职业能力
  • 简介:OriginsTheDongxiangminoritygetsitsnamefromageographicallocation.ThetermDongxiangusedtorefertothevillageseastofHezhouCity(today’sLinxiainGansuProvince).ThereignofQingEmperorKangxisawthedivisionoffourtownshipscenteredonHezhouintoeast,north,westandnorth.respectively.TheeasternpartwasthusnamedDongxiang("easternvillages").Thequestionofthisminority’soriginswasoncethesubjectofgreatdisagreement,butovertheyears,thepredominant

  • 标签: 族群 地点 中国 人物 地理位置 东乡族
  • 简介:ThelackofastableanalyticalframeworkisthemainreasonwhyacademiccircleshavenotbeenabletokeepanhistoricalandobjectivegraspofRussia-U.S.relations.InordertomakeanacademicanalysisofRussia-U.S.relationswemustnotsimplyrelyonpoliticalstatements,butwemustalsotakeintoaccountbasicvariablesthatcanaffecttherelationship.

  • 标签: 美国总统 普京 国际关系 克里姆林宫 俄罗斯 决定性
  • 简介:Amorphoussilicon(a-Si),nanocrystallinesilicon(nc-Si)andhydrogenatednanocrys-tallinesilicon(nc-Si:H)filmswerefabricatedbyusingchemicalvapordeposition(CVD)system.Thea-Siandnc-Sithinfilmswereirradiatedwith94MeVXe-ionsatfluencesof1.0×1011ions/cm-2,1.0×1012ions/cm-2and1.0×1013ions/cm-2atroomtemperature(RT).Thenc-Si:Hfilmswereirradiatedwith9MeVXe-ionsat1.0×1012Xe/cm-2,1.0×1013Xe/cm-2and1.0×1014Xe/cm-2atRT.Forcomparison,mono-crystallinesilicon(c-Si)sampleswerealsoirradiatedatRTwith94MeVXe-ions.AllsampleswereanalyzedbyusinganUV/VIS/NIRspectrometerandanX-raypowderdiffractometer.Variationsoftheopticalband-gap(Eg)andgrainsize(D)versustheirradiationfluencewereinvestigatedsystematically.Theobtainedresultsshowedthattheopticalband-gapsandgrainsizeofthethinfilmschangeddramaticallywhereasnoobservablechangewasfoundinc-SisamplesafterXe-ionirradiation.Possiblemechanismunderlyingthemodificationofsiliconthinfilmswasbrieflydiscussed.

  • 标签: NC-SI H薄膜 离子辐照 A-SI 光学带隙 改造
  • 简介:February27,2012markedthe40thanniversaryoftheShanghaiCommuniqué.Beforetheanniversary,Mr.XiJinpin,China’sVicePresident,visitedtheUnitedStatesinmidFebruary,settingoffawaveofcommemorationofthe'ShanghaiCommuniqué'inbothChinaandtheUnitedStates.

  • 标签: 上海 发行 习近平 副主席 中国 美国
  • 简介:BackgroundAfterpercutaneouscoronaryintervention(PCI),somepatientsmaysufferfromrestenosisandstentthrombosis.Manystudiessuggestthatendothelialprogenitorcell(EPC)hasanimportantroleinpreventingrestenosisandstentthrombosis.AnovelstentwhichcanattractEPChasbeendesignedtoprovideabetteroutcomefortheseproblems.MethodThedataofthepresentreviewwasobtainedbysearchingPUBMEDandotherdatabases(1994-2011)usingthekeytermsof'endothelialprogenitorcell','reendothelialization','restenosis','stentthrombosis',and'percutaneouscoronaryintervention'.ResultRapidreendothelializationisessentialinpreventingrestenosisandstentthrombosis.EPCcandifferentiateintoendothelialcellandacceleratethereendothelialization.Afternumerouspreclinicalandclinicalresearches,thecorrelationbetweencirculatingEPCstorestenosisstillremainspoorlyunderstood.However,manystudieshaveshowntheimportantroleofEPCindiminishingtheriskofthrombosisfollowingstentimplantation.Somepharmacologicalagentshavebeenreportedcanincreasethenumberand/orfunctionsofEPC.Recently,CD34+antibodycoatedstenthasbeendevelopedtoattractEPCtothehealingendothelium,andhasshowedfavorableresults.ConclusionEPChasimportantroleinrapidreendothelializationaftervascularinjury.EPCcanpreventstentthrombosisafterPCI,howevertheeffectsofEPCinpreventingrestenosisneedfurtherinvestigations.ThecapturingCD34+stentissafeandsignificantlydecreasesstentthrombosis.

  • 标签: 内皮祖细胞 血栓形成 冠状动脉 后支架 介入治疗 再狭窄
  • 简介:ThispaperpresentsastudyonthetemporalandspatialvariationsoftheprecipitationovertheareaoftheSouthChinaSea(SCS)duringthemonsoononsetperiod.ThedatausedarefromtheTropicalRainfallMeasuringMission(TRMM)observationsbetweenAprilandJuneoverthenineyearsfrom1998to2006.ThisstudyfocusesonthecentralandnorthernpartofSouthChinaSea(110-120°E,10-20°N).Basedontheobservations,the27thpentadisselectedastheoccurrencetimeoftheSCSmonsoononset.Theconclusionsareasfollows.(1)Afterthemonsoononset,thespecificarea,definedastheratioofthenumberofpixelswithcertaintypeofprecipitationtothenumberoftotalpixels,extendssignificantlyforbothconvectiveandstratiformrain,withthelatterhavingalargermagnitude.Thespecificrainfall,definedastheratiooftheamountofcertaintypeofprecipitationtothetotalamountofprecipitation,decreasesforconvectiverainandincreasesforstratiformrain.(2)Resultsalsoshowsignificantincreaseinheavyrainanddecreaseinlightrainafterthemonsoononset.(3)ChangesarealsoobservedintherainfallhorizontaldistributionsovertheSCSbeforeandafterthemonsoononset,manifestedbytherelocationofprecipitationminimaforbothconvectiveandstratiformrain.(4)Afterthemonsoononset,thevariabilityincharacteristicsofprecipitationverticalstructureincreasessignificantly,leadingtomorelatentheatreleaseandconsequentlydeeperconvection.Meanwhile,thebright-bandaltitudeofstratiformprecipitationisalsoelevated.

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  • 简介:Amathematicalmodelhasbeenformulatedinaccordancewithcellchemotaxisandrelevantexperimentaldata.Athree-dimensionallatticeBoltzmannmethodwasusedfornumericalsimulation.Thepresentstudyobservedtheeffectsofglialscarsizeandinhibitorconcentrationonregenerativeaxonalgrowthfollowingspinalcordtransection.Thesimulationtestcomprisedtwoparts:(1)whenreleaseratesofgrowthinhibitorandpromoterwereconstant,theeffectsofglialscarsizeonaxonalgrowthratewereanalyzed,andconcentrationsofinhibitorandpromoterslocatedatthemovinggrowthconeswererecorded.(2)Whentheglialscarsizewasconstant,theeffectsofinhibitorandpromoterreleaseratesonaxonalgrowthratewereanalyzed,andinhibitorandpromoterconcentrationsatthemovinggrowthconeswererecorded.Resultsdemonstratedthat(1)alargerglialscarandahigherreleaserateofinhibitorresultedinareducedaxonalgrowthrate.(2)Theaxonalgrowthratedependedontheratioofinhibitortopromoterconcentrationsatthegrowthcones.Whentheaverageratiowas<1.5,regeneratingaxonswereabletogrowandsuccessfullycontacttargetcells.

  • 标签: 生长抑制剂 轴突再生 脊髓损伤 瘢痕 胶质 浓度
  • 简介:Objective:ToinvestigatewhetherGli1expressionisimportantinrelapseafterradicaloperationofbreastcancer.Methods:Usingimmunohistochemistry,Gli1expressionwasanalyzedinhumanprimarybreastcancer(n=284)andparacanceroustissues(n=20),andalsoinlocallymphnodes(n=28)andmetastaticlymphnodes(n=28).Results:InitialanalysisofGli1expressioninasmallcohortof20breasttumorsandtheirparacanceroustissuesshowedatendencytowardsGli1overexpressioninbreastcancertissues(P<0.001).Further,Gli1expressionin284breastcancertissuesampleswasanalyzedandasignificantcorrelationwasfoundbetweenincreasedexpressionofnuclearGli1andunfavorablerecurrence-freesurvival(RFS)(P<0.05).ThenuclearexpressionofGli1inmetastaticlymphnodesfollowingrelapseafterradicaloperationwasmuchhigherthanthatinthelocallymphnodesofprimarycarcinoma(P<0.05).Mostinterestingly,theexpressionofGli1wasmuchhigherintheinterstitialtissuesoftherelapsedgroupthanofthenon-relapsedgroup(P<0.001).Conclusions:BreastcancershowsahighprevalenceofGli1expression,whichissignificantlycorrelatedwithaggressivefeaturesandunfavorableRFS.NuclearGli1overexpression,especiallyintheinterstitialtissues,signifiedearlyrelapseafterradicaloperationofbreastcancer.

  • 标签: 手术切除 乳腺癌 过度表达 复发 辅助治疗 早期
  • 简介:尖锐的圣举起心肌的梗塞有高死亡和病态率。有这张条件脸的病人的多数除了另外的健康问题的可勃起的机能障碍。在这研究,我们试图调查二不同灌注策略,主要angioplasty和thrombolytic治疗的效果,在在尖锐心肌的梗塞以后的可勃起的机能障碍的流行上。匹配选择标准的71个病人,45与stenting与主要冠的angioplasty被对待,并且26与thrombolytic代理人被对待。可勃起的功能在医院里用可勃起的功能的国际索引被评估在事件以后在尖锐心肌的梗塞和6个月前描绘每个病人的性功能。要求恢复血流动到梗塞影响的动脉的时间被发现在尖锐心肌的梗塞以后与可勃起的机能障碍的出现被联系。在尖锐心肌的梗塞以后的可勃起的机能障碍的流行的增加是44.4%;在angioplasty组和76.9%;在thrombolytic治疗组(P=0.008)。在结论,这研究显示出那减少灌注减少的时间可勃起的机能障碍流行,和主要angioplasty比为减少的thrombolytic治疗优异在尖锐心肌的梗塞以后的可勃起的机能障碍的流行。

  • 标签: 急性心肌梗死 勃起功能障碍 血管成形术 溶栓药物 治疗 ST
  • 简介:在Brassicaceae的摘要,myrosinase催化glucosinolate的水解作用并且在反草食动物防卫起一个重要作用。我们从从另外的Brassica种类与myrosinase基因展出高顺序身份的Brassicaparachinensis克隆并且描绘myrosinase基因的全身的互补DNA。对有菱形斑纹的蛾(Plutellaxylostella)在防卫调查这myrosinase的角色,我们构造了RNA干扰(RNAi)表示指向了myrosinase和transfected的双strandedRNA的盒子它进B。parachinensis。Myrosinase在结果被压制转基因的工厂。在转基因的工厂上喂的有菱形斑纹的蛾幼虫比在非转基因的工厂上喂的那些有更低的幼虫、蛹的重量,更长蛹的持续时间,和更低的肥沃,建议有菱形斑纹的蛾使防御系统适应了glucosinolate-myrosinase。因此,myrosinase的抑制是为控制有菱形斑纹的蛾的一条潜在的途径。

  • 标签: 小菜蛾幼虫 防御作用 酶基因 黑芥 菜心 转基因植物
  • 简介:BackgroundAnomalousoriginoftheleftcoronaryarteryfromthepulmonaryarteryisararecongenitalcardiaclesionresultinginmyocardialischemiaeveninfarction,morphologicalimpairmentanddysfunctionofleftventricle,togetherwithmitralregurgitation.Herewewillintroduceourexperienceinthesurgicalrepairofthiskindofcongenitallesionandtheretrospectiveanalysisabouttheimprovementofleftventriculardimensionandmitralregurgitationinearlypostoperativeterm.MethodFromMay1998toJuly2012,38consecutivepatientswithanomalouscoronaryarteryfromthepulmonaryarteryunderwentsurgicalcorrection(33receivedleftcoronaryarteryre-implantation,4leftcoronaryarteryligationorprimaryclosure,1Takeuchiprocedure,and10simultaneousmitralvalveplasty).Leftventriculardimension,mitralregurgitation,andejectionfraction,weremeasuredbycolorDopplerechocardiographypreoperatively,and1monthafterdischarge.ResultsHospitalsurvivalwas94.7%(2in-hospitaldeaths).Tenpaptientswithmorethanmoderatemitralregurgitationreceivedsimultaneousmitralplasty,oneofwhomwasconvertedtomechanicalprostheticvalvereplacement.Mitralvalveannuloplastywasappliedin9casesofcoronaryre-implantationcorrection,3ofwhomalsoreceivedadditionalmitralleafletcleftrepair.Meanwhile8patientsunderwentotherdifferentconcomitantoperations.Echocardiographicresultsforthesurvivals1monthafterdischargeshowedthatleftventricularend-diastolic,endsystolicdimensiondecreasedfrom40.05±5.56mmand28.94±6.21mmto33.07±6.82mm(P<0.01)and23.04±5.87mm(P<0.01)respectively.Theaveragemitralregurgitationgradewasalsoreducedfrom2.36±1.08to1.64±93(P<0.05)inthegroup.AllsurvivalpatientsimprovedclinicallyandNYHAfunctionalclassdecreasedsignificantlyfrom2.37±1.08to2.10±0.54(P<0.05).ConclusionsThesurgicalrepairofanomalousoriginoftheleftcoronaryarteryfromthepulmonaryarteryissafeandeffective,andcange

  • 标签: 冠状动脉 二尖瓣 左心室 肺动脉 关闭 尺寸
  • 简介:BackgroundThefactorsinfluencingtheq-wavechangesinV5andV6duringanterioracutemyocardialinfarction(AMI)havenotbeenthoroughlydescribed.MethodsWestudied70patientswithafirstanteriorAMI,inwhomtheelectrocardiogram(ECG)showedeitherdisappearanceofthenormalseptalqwave(n=24)orpresenceofpathologicalQwaveinV5andV6(n=46)duringfollow-up.TheECGandcoronaryangiographyfindingswerecorrelated.ResultsTherewasnodifferencebetweenthe2groupsintheculpritsiteproximaltoS1(46%vs.36%,P=0.405),buttheculpritsitewasmorefrequentlylocatedproximaltoD1inthegroupwithabnormalQwave(21%vs.67%,P=0.001).Patientswithdisappearanceoftheseptalqwavemoreoftenhadalargeobtusemarginalbranch(46%vs.22%,P=0.037)anddisappearanceoftherwaveinV1(88%vs.7%,P=0.001).PatientswithabnormalQ-wavemoreoftenhadalargeLAD(42%vs.71%),smallrwaveortallorwideRwaveinV1(0%vs.89%,P=0.001)andabnormalQwavesintheinferiorleads(33%vs.59%,P=0.044).ConclusionsInpatientswithfirstanteriorAMI,qwavechangesinV5andV6correlatedwiththemorphologyinV1.EmergingabnormalQwaveinV5/V6predictedtheculpritlesioninalargeLADproximaltoD1,butdisappearanceoftheseptalqwavecouldnotpredicttheculpritlesionproximaltoS1.

  • 标签: 急性心肌梗死 心电图 异常 冠脉造影 发病 外观