简介：【摘要】 目的 分析在纵隔肿瘤的胸腔镜治疗中，应用自主呼吸静脉麻醉与常规双腔气管插管静脉吸入复合麻醉的应用效果。方法 选取我院于 2018年 12月 ~2019年收支的纵隔良性肿瘤患者进行分析，随机分为 2组。给予对照组患者常规双腔气管插管静脉吸入复合麻醉方式下进行胸腔镜手术，切除纵隔肿瘤。观察组则应用自主呼吸静脉麻醉方式。对比两组患者的围术期指标。结果 观察组患者的围术期指标明显优于对照组患者，差异具有统计学意义（ P<0.05）。结论 在纵隔肿瘤的胸腔镜治疗中应用自主呼吸静脉麻醉，能减少麻醉插管时间，促进患者的恢复，值得推广应用。

简介：【摘要】目的 探讨双歧杆菌四联活菌片联合三联疗法治疗儿童幽门螺杆菌感染的临床疗效。方法 选取 2019年 3月 ~2020年 4月在我院进行治疗的幽门螺杆菌超标的儿童 100例进行观察研究，根据随机分配的原则将 100例患者分为观察组和对照组，每组各 50例。对照组患者采用奥美拉唑对患者进行治疗，观察组患者则采用双歧杆菌四联活菌片联合三联疗法对幽门螺杆菌感染的儿童进行治疗。通过对比两组患者的并发症发生率及治疗效果进行评判，判断双歧杆菌四联活菌片联合三联疗法治疗儿童幽门螺杆菌感染的临床疗效。结果 观察组患者的并发症发生率低于对照组患者，观察组患者的治疗效果高于对照组患者，差异显著（ p ），有统计学意义。结论 通过对比两组患者的研究结果，证明双歧杆菌四联活菌片联合三联疗法治疗儿童幽门螺杆菌感染的临床疗效良好，能够有效的减少患者的不良反应发生率，降低患者及患者家属的心理压力，提升医院的治疗效率，是患者及患者家属放心的优质护理方案，具有很高的临床学价值，值得临床推广用。

简介：　　 [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月～ 2020年 1月我院收治的溃疡性结肠炎患者 80例，随机分为两组，每组各 40例，两组患者均予常规对症治疗，同时两组均予美沙拉嗪缓释颗粒，观察组同时加用双歧三联活菌胶囊，治疗后比较两组患者治疗后的临床疗效，以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%，显著高于对照组的总有效率 70.00%，两组疗效比较差异具有显著性（ P<0.05）。治疗后，两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低（ P<0.05）。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组（ P<0.05）。观察组患者治疗后的临床症状积分为（ 2.56±0.85）分，与治疗前及对照组比较，差异有统计学意义（ P<0.05）。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切，且可以抑制炎症反应，值得临床推广和应用。  　　 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子  　 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.