outcomes of treatment of sudden deafness using different protocols: a retrospective analysis of 104 cases

(整期优先)网络出版时间:2010-01-11
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ObjectiveTocomparedifferenttreatmentprotocolsforsuddendeafness(SD),forthepurposeofidentifyinganappropriateapproachtoSD.MethodsAtotalof104patientswithdiagnosisofsuddenhearinglosstreatedfromJan2006toDecember2008wereincludedinthisstudy,ofwhich31receivedthetypicalpharmaceuticaltreatment(groupⅠ),40receivedthetypicalpharmaceuticaltreatmentpluspolarizedliquid(GroupⅡ)and33receivedthehyperbaricoxygeninadditiontothetreatmentincludedinGroupⅡ(GroupⅢ).ResultsThetotalimprovementrate(67.74%,62.50%and75.76%forGroupsⅠ,ⅡandⅢrespectively)wasnotstatisticallydifferentbetweenthethreegroups(P>0.05).ConclusionThethreetreatmentprotocolsaresimilarwhenjudgedbythetreatmentoutcomesinSD,neitherbeingsuperiortotheothers.Thetwoimportantfactorsthatappeartoinfluencetreatmentoutcomesaretheaudiogrampatternanddurationofhearinglossbeforeseekingtreatment.Patientswithupslopingorpeak-typeaudiogramsandtreatedwithin7daysfromtheonsethavebetterprognosisthanothers.