Inthispaper,theselectiveadsorptionofLDLonchitosanmodifiedwithPEGandAsp.wasstudied.TheadsorptionrateofLDLandHDLonthedoublemodifiedchitosanwas57%and12%respoectively,TheresultsshownthatthedoublemodifiedchitosancanbeusedaadsorbentforselectivebindingtoLDL,thisworkmayhelptodevelopfunctionalcolumnsforhemoperfusion.