食管癌的治疗进展

(整期优先)网络出版时间:2001-03-13
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IntroductionManagementofesophagealcancerhasseenmuchprogressinthepasttwodecades.Thereusedtobeonlythreetreatmentoptionsforpatientssufferingthisdeadlydisease:surgicalresection,externalirradiationtherapy,andintubationwithplasticprosthesis.Forthosewithterminaldisease,agastrostomytubewasofteninserted.Thiswasanunsatisfactoryprocedureforitmerelyprolongedlifewithoutmeaningfulpalliation.Inrecentyears,surgicalresectionhasbeenrefined,techniquesofradiationimproved,neoadjuvantoradjuvanttherapieswithchemotherapyand/orradiotherapyadded,andvariousnewmethodsofendoscopicproceduresmadeavailableforpalliation.Foreachpatient,thebestsingleorcombinationoftreatmentshastobeinpidualized.Therapeuticoptionsforesophagealcancerhaveindeedincreased.Therearethreemainareasinwhichprogressismostevident:theyaresurgicalresection,multimodalitytreatment,andendoscopicpalliation.