InthispaperweprovesomeinterestingextensionsandgeneralizationsofEnestrom-KakeyaTheoremconcerningthelocationofthezerosofapolynomialinacomplexplane.Wealsoobtainsomezero-freeregionsforaclassofrelatedanalyticfunctions.Ourresultsnotonlycontainsomeknownresultsasaspecialcasebutalsoavarietyofinterestingresultscanbededucedinaunifiedwaybyvariouschoicesoftheparameters.