简介:研究目的:探讨高住低练对大鼠骨髓细胞促红细胞生成素受体(Erythropoietinreceptor,EpoR)蛋白表达的不同作用。研究方法:本研究将健康雄性SD大鼠56只随机分为7组,采用免疫组织化学及计算机显微图像分析,检测EpoR在骨髓组织中的含量,分析运动和低氧2种不同的处理因素对骨髓EpoR蛋白表达的效应。研究结果:高住低练和低住低练都可使EpoR蛋白表达增加。高住低练中随着训练时间的延长,EpoR增加更明显。结论:随着低氧和训练因素的影响,EpoR蛋白有逐渐上升的趋势,模拟高住低练能使EpoR蛋白表达加快。
简介:Background:Overweightandobesityhasbecomeaseriouspublichealthprobleminmanypartsoftheworld.Studiessuggestthatmakingsmallchangesindailyactivitylevelssuchas"breaking-up"sedentarytime(i.e.,standing)mayhelpmitigatethehealthrisksofsedentarybehavior.Theaimofthepresentstudywastoexaminetimespentinstanding(determinedbycountthreshold),lying,andsittingpostures(determinedbyinclinometerfunction)viatheActiGraphGT3Xamongsedentaryadultswithdifferingweightstatusbasedonbodymassindex(BMI)categories.Methods:Participantsincluded22sedentaryadults(14men,8women;meanage26.5±4.1years).Allsubjectscompletedtheself-reportInternationalPhysicalActivityQuestionnairetodeterminetimespentsittingovertheprevious7days.Participantswereincludediftheyspentsevenormorehourssittingperday.PosturesweredeterminedwiththeActiGraphGT3Xinclinometerfunction.Participantswereinstructedtoweartheaccelerometerfor7consecutivedays(24haday).BMIwascategorizedas:18.5to<25kg/m2asnormal,25to<30kg/m2asoverweight,and≥30kg/m2asobese.Results:Participantsinthenormalweight(n=10)andoverweight(n=6)groupsspentsignificantlymoretimestanding(afteradjustmentformoderate-to-vigorousintensityphysicalactivityandwear-time)(6.7hand7.3hrespectively)andlesstimesitting(7.1hand6.9hrespectively)thanthoseinobese(n=6)categories(5.5hand8.0hrespectively)afteradjustmentforwear-time(p<0.001).Therewerenosignificantdifferencesinstandingandsittingtimebetweennormalweightandoverweightgroups(p=0.051andp=0.670respectively).Differenceswerenotsignificantamonggroupsforlyingtime(p=0.55).Conclusion:Thisstudydescribedposturalallocationsstanding,lying,andsittingamongnormalweight,overweight,andobesesedentaryadults.Theresultsprovideadditionalevidencefortheuseofincreasingstandingtimeinobesitypreventionstrategies.