简介：Irradiationfromdiversesourcesisubiquitousandcloselyassociatedwithhumanactivities.Radiationtherapy(RT),animportantcomponentofmultipleradiationorigins,isacommontherapeuticmodalityforcancer.Moreimportantly,RTprovidessignificantcontributiontooncotherapybykillingtumorcells.However,duringthecourseoftherapy,irradiationofnormaltissuescanresultinawiderangeofsideeffects,includingself-limitedacutetoxicities,mildchronicsymptoms,orsevereorgandysfunction.Althoughnumerouspromisingradioprotectiveagentshaveemerged,onlyafewhavesuccessfullyenteredthemarketbecauseofvariouslimitations.Atpresent,thewidelyacceptedhypothesisforprotectionagainstradiation-causedinjuryinvolvestheWntcanonicalpathway.ActivatingtheWnt/β-cateninsignalingpathwaymayprotectthesalivarygland,oralmucosa,andgastrointestinalepitheliumfromradiationdamage.Theunderlyingmechanismsincludeinhibitingapoptosisandpreservingnormaltissuefunctions.However,aberrantWntsignalingunderliesawiderangeofpathologiesinhumans,anditsvariouscomponentscontributetocancer.Moreover,studieshavesuggestedthatWnt/β-cateninsignalingmayleadtoradioresistanceofcancerstemcell.ThesefactsmarkedlycomplicateanydefinitionoftheexactfunctionoftheWntpathway.

简介：InthearticletheauthorlooksbacktheharddevelopmentcourseandgreatprogressinearthquakescienceandtechnologyinChinaduringthelastnearahalfofcenturyandexpoundsthefollowing3aspects:(1)Thestrongdesireofthewholesocietytomitigateseismicdisastersandreducetheeffectofearthquakesonsocial-economicliveisagreatdrivingforcetopushforwardthedevelopmentofearthquakescienceandtechnologyinChina;(2)Tobetterensurepeople'slifeandproperty,sustainableeconomicdevelopment,andsocialstabilityisanessentialpurposetodrivethedevelopmentofearthquakescienceandtechnologyinChina;and(3)Toinsistonthedialecticalconnectionofsetupoftechnicalsystemforseismicmonitoringwiththescientificresearchofearthquakesandtobetterhandletherelationbetweencrucialtask,currentscientificlevel,andthefeasibilityaretheimportantprinciplestoadvancetheearthquakescienceandtechnologyinChina.Somesuccessandmanysetbacksinearthquakedisastermitigationconsistentlyenrichourknowledgeregardingthecomplexityoftheconditionsforearthquakeoccurrenceandtheprocessofearthquakepreparation,promotethereconstructionandmodernizationoftechnicalsystemforearthquakemonitoring,anddeepenthescientificresearchofearthquakes.Duringthelast5years,theimprovementandmodernizationoftechnicalsystemforearthquakemonitoringhaveclearlyprovidedthetechnicalsupporttostudyandpracticeofearthquakepredictionandprecaution,giveprominencetokeyproblemsandbroadenthefieldofscientificresearchofearthquakes.Thesehaveenabledustogetsomenewrecognitionoftheconditionsforearthquakeoccurrenceandprocessofearthquakepreparation,characteristicsofseismicdisaster,andmechanismforearthquakegenerationinChina'scontinent.Theprogresswehavemadenotonlyencouragesustoenhancetheeffectivenessofearthquakedisastermitigation,butalsoprovidesabasisforacceleratingfurtherdevelo

简介：Basedontheinvestigationoftheluminescenceofaseriesofrareearthorganicchelates,somerelationshipsbetweenluminescenceandthestructureofthechelateswereproposed:theintensityofsensitizedluminescenceofcentrallanthanideions(Ln3+)inarareearthorganicchelatedependson(1)thesuitabilityoftheenergygapbetweentheexcitedtripletenergyleveloftheligandsandthelowestexcitedenergylevelofLn3+ions;(2)therigidityandplanarityofthestructureofthechelatemolecule;(3)theexistenceofasuitablesecondaryligandwhichmayincreaserigidityandthestabilityofthechelatemolecule;and(4)theexistenceofasuitableπ-conjugatedsysteminthechelatemolecule.Accordingtotheaboverelationships,25novelorganicligandsweredesignedandsynthesized,andtheirlanthanidechelateswereprepared.Investigationofthephotoluminescenceforthenewchelatesshowsthatsomeofthechelatesarestronglyluminescent,andareappliedtofluoroimmunoassayfordeterminationofhumanimmunoglobulin(IgG),topreparationoffluorescentplastics,andtodeterminationofgrowthhormoneforplants.Twonovelspectroscopy-probetechniquesforstructureofcoordinationcompoundsandbiologicalmoleculeswereproposedanddevelopedbasedonvibronicspectroscopyofTb3+complexesandfluorescenceofCe3+.

简介：AbstractEtiology of adolescent idiopathic scoliosis (AIS), a complicated three-dimensional spinal deformity with early-onset, receives continuous attention but remains unclear. To gain an insight into AIS pathogenesis, this review searched PubMed database up to June 2019, using key words or medical subject headings terms including "adolescent idiopathic scoliosis," "scoliosis," "pathogenesis," "etiology," "genetics," "mesenchymal stem cells," and their combinations, summarized existing literatures and categorized the theories or hypothesis into nine aspects. These aspects include bone marrow mesenchymal stem cell studies, genetic studies, tissue analysis, spine biomechanics measurements, neurologic analysis, hormone studies, biochemical analysis, environmental factor analysis, and lifestyle explorations. These categories could be a guidance for further etiology or treatment researches to gain inspiration.

简介：Thispapersummarizes,fromaglobalperspective,themajorprogressintheimplementationoftheAgenda21sincetheUNConferenceonEnvironmentandDevelopment.Theresultsshowthatglobaleconomyhasachievedasubstantialgrowth,andpositiveprogresshasbeenmadeinpovertyeradication,urbanization,andconservationandintensiveuseofnaturalresources.However,relevantinternationalconventionsandcommitmentshavenotyetbeencompletelyfulfilled.Thepaperfurtheranalyzesthecurrentmajorchallengesandfuturetrendsofglobalsustainabledevelopment.Itisarguedthattherearethreemajorchallenges:1)fatalglobalenvironmentalissuesposinganincreasingthreattohumansurvival;2)moreandmoresevereglobalcompetitionfordevelopingspaces;and3)issueshighlightingglobalpeople'slivelihood.Therearefourtrendsofglobalsustainabledevelopment:1)sustainabledevelopmentwillfurtherturnfromconceptintoglobalaction;2)greenwillbethemaintrendofglobaldevelopment;3)emergingdevelopingcountrieswillbecomethemaindrivingforceofglobalsustainabledevelopment;and4)internationalrelationsinthefieldofsustainabledevelopmentwillturntocompetitiveco-operation.

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简介：ForewordRespectingandprotectinghumanrightsisaconstitutionalprincipleinChina.ItalsoreflectsthewillandpursuitoftheCommunistPartyofChina(CPC),theChinesegovernmentandtheChinesepeople.Thejudiciaryisthelastlineofdefensetosafeguardsocialfairnessandjustice,andjudicialprotectionofhumanrightsisanimportant

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简介：Occlusaldisordercausedbysevereworndentitionisoneofthemostcommondiseasesintheocclusion.Occlusalreconstructionisanimportantrepairmethod,referringtomodifyandrebuildtheexistingocclusionstatus,thentorestoretheocclusion.Duringocclusalreconstruction,thedigitalocclusionanalysissystemcanaccuratelyacquiretheocclusionstatus,inordertoguidethereconstructionocclusionaccuratelyandrestorethenormalfunctionoftheoralmaxillarysystem.Thispaperreviewstheconceptofocclusalreconstruction,sequencetherapy,traditionalocclusionanalysismethodsandthedevelopmentstatusandprospectofdigitalocclusionanalysis.

简介：ForewordTheyear2003wasanimportantandunusualyearforChina’sdevelopment.Itwasalsoayearofgreat,landmarksignificanceforprogressinhumanrightsinthecountry.In2003,theChineseGovernmentdidagoodjobintacklingthesuddenoutbreakofSARSandcurbingitsspread,aswellasintacklingfrequentnaturaldisasters.Persistingintakingeconomicconstructionasitscentraltask,andstrivingfor

简介：Cancerisaleadingcauseofdeathworldwide.Cancertreatmentsbychemotherapeuticagents,surgery,andradiationhavenotbeenhighlyeffectiveinreducingtheincidenceofcancersandincreasingthesurvivalrateofcancerpatients.Inrecentyears,plant-derivedcompoundshaveattractedconsiderableattentionasalternativecancerremediesforenhancingcancerpreventionandtreatmentbecauseoftheirlowtoxicities,lowcosts,andlowsideeffects.Ellagicacid(EA)isanaturalphenolicconstituent.RecentinvitroandinvivoexperimentshaverevealedthatEAelicitsanticarcinogeniceffectsbyinhibitingtumorcellproliferation,inducingapoptosis,breakingDNAbindingtocarcinogens,blockingvirusinfection,anddisturbinginflammation,angiogenesis,anddrug-resistanceprocessesrequiredfortumorgrowthandmetastasis.ThisreviewenumeratestheanticarcinogenicactionsandmechanismsofEA.ItalsodiscussesfuturedirectionsontheapplicationsofEA.

简介：Involuntaryresettlementcausedbyprojectconstructionisadifficultproblemovertheworld.Inthepast,therestorationoflivelihoodsintheeventofinvoluntaryresettlementhasbeenbasedpurelyonprovidingcompensationtothosewhoaredisplaced.Evidencehasshownthatcompensation-basedinvoluntaryresettlementcannotrealizetheobjectiveofrestoringandimprovingresettlers'livingstandard.Withaviewtoimprovethisoutcome,thecon-ceptofResettlementwithDevelopment(RwD)wasenvisagedandisnowgenerallyheraldedasthemeanstomitigatethecatastrophicfailuresofthepast.However,fewdevelopingcountrieshaveincludedtheconceptofRwDintotheirnationalpoliciesandChinaisoneofthem.TheChinesegovernmenthastakenresettlementasanopportunitytohelpresettlersrestoreandimprovetheirlivingstandardsanddevelopeconomyinreservoirareasbyimplementingRwDpolicyincludinggivingcompensationandsubsidiesatearlystageandofferingproductionassistanceatlatestage,settingupreservoirconstructionfund,initiatingpartnershipprogramsandpreferentialpolicyaswellasenhancinginfrastructureconstruction.ThepreliminaryexperiencefromtheTGPresettlementhasverifiedthatthetransformationfromcompensation-basedresettlementtoRwDisarightpolicychoice.Meanwhile,becauseofthechangingpoliticalenvironmentandthecomplexityofinvoluntaryresettlementthereisstillroomforChinatoimproveitsRwDpolicy.

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简介：Ithasn’tbeeneasy,butalmostalloftheworkontheThreeGorgesProjectisonschedule,accordingtoacorporationoverseeingconstructionofthedam.TheChinaYangtzeThreeGorgesProjectDevelopmentCorporationhasreportedthatcontractorsandotherstaffareworkinghardtoensurethatthefloodseasondoesnotslowthedamproject.Thecompanyrecentlydetailedthemammothtasksthathavetakenplacesofar

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简介：Permanentmagneticmaterialscapableofoperatingathightemperatureupto500°Chavewidepotentialapplicationsinfieldssuchasaeronautics,space,andelectroniccars.SmCoalloysarecandidatesforhightemperatureapplications,sincetheyhavelargemagnetocrystallineanisotropyfield(6–30T),highCurietemperature(720–920°C),andlargeenergyproduct([200kJám-3)atroomtemperature.However,thehighestservicetemperatureofcommercial2:17typeSmComagnetsisonly300°C,andmanyeffortshavebeendevotedtodevelopnovelhightemperaturepermanentmagnets.ThisreviewfocusesonthedevelopmentofthreekindsofSmCobasedmagnets:2:17typeSmComagnets,nanocrystallineSmComagnets,andnanocompositeSmComagnets.Theoxidationprotection,includingalloyingandsurfacemodification,ofhightemperaturepermanentmagnetsisdiscussedaswell.

简介：Strategicenvironmentalassessment(SEA)inChinahasdevelopedrapidlysinceitwasintroducedintoChinainthe1990s.ChinesegovernmentpromulgatedtheEnvironmentalImpactAssessmentLawofChina(hereinafterreferredtoastheEIALaw)in2002.Inthislaw,itisstipulatedclearlythatregionalandsectorplansshouldbeassessed.Throughinvestigatingmaterialsandanalyzingliteratures,thisarticleanalysesthepracticalandacademicstudyachievementsofSEAinChinathathavebeenachievedsincetheEIALawwasimplemented,probesintothecurrentsituationofthemainlevelofSEAinChina-planEIA,thensummarizesthedevelopmentcharacteristics,andeventually,putsforwardthedevelopmenttrendsofSEAinChina.TheresearchconclusionscanofferthefoundationsforcomprehendingsystematicallytheprogressofSEAinChina.

简介：Inlinewiththerapidlyexpandingelectricpowerindustryinthiscountry,Chinanowownsaworkforcetotalingmorethanhalfamillionofstaffandworkersengagedintheconstructionofthermalpowerprojects;alsothetechnologyemployedintheirworkhasexperiencednotableprogress.Intheearlyfifties,constructionworkmainlyreliedonmanualmanipulation.Besidestheuseofhand-orelectric-drivenover-headcranesinsidethemachine-house,verticaltransporta-tiondependedmainlyonhoistersandpulleys;chainblockswerescarceatthattime.Horizontaltransportationwasmainlydonebymanualpulley-blocksandrollers,sometimesalsowithwinches.Electric-orgas-weldingbyhandwasthecommonprac-tice.Inaword,thetechnologywasbackwardandlabor-inten-

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