简介：ItisanewresearchtopictocreatearationaljudgmentmatrixusingthecognitiontheorybecauseoftheconstructionofjudgmentmatrixinAHPinvolvingthedecision-maker'scognitiveactivities.Owingtothepresenceofuncertaininformationinthedecisionprocedure,theimproperuseoftheuncertaininformationwilldoubtlesscauseweightchanges.Inthispaper,weaddafeedforwardprocesspriortoconstructingthejudgmentmatrixsothatthedecisionmakercanuseboththecertainanduncertaininformationtogettheinitialuncertainroughjudgmentmatrix,andthenconvertitintoafuzzymatrix.Consequently,itwillbebetterfordecisionmakertoobtaintheroughsetoforderequivalentclassesthroughthedecisiongraph.Accordingtothequalitativeanalysis,thedecisionmakercaneasilyconstructthefinaljudgmentmatrixinstructedbytheroughsetcreatedearlier.

简介：Withthecurrentworldorderbeingdismantledandthenewyettobebuilt,majorcountriesfacingvariousdifficultieshavesharplydifferingexpectationsforthefuture.Evenasitsglobalinfluenceaccrues,theriskassociatedwitheconomicdecelerationisobjective.ForChina,theoutlookonworldorderandtheworldsystemiscloselyrelatedtopastexperienceandpresentreality,andconstructionofaneworderrequiresinternationalsolidarityandcooperation.S

简介：1.IntroductionFirstofall,let’srecallthedefinitionsofsymplecticschemes,revertibleschemes,andFeng’swayofconstructionofsymplecticmethodsviageneratingfunctions.Aswell-known,thephaseflow{g’,tER}ofanyHamiltoniansystem(whereJ~I--i:n1,H:RZn--+RIisasmoothfunc...

简介：在这篇论文，基于高顺序的速度精力，集成和变化原则的定理，高顺序的哈密尔顿一般holonomic系统的原则被给。然后，三顺序的Lagrangian方程和四顺序的Lagrangian方程从高顺序的哈密尔顿的原则被获得。最后，哈密尔顿高顺序的Lagrangian功能的原则被给。

简介：介绍为菲希尔构造了有限差别计划的一个班的研究部分微分方程。逻辑方程的解决方案的性质；高保真度算法的建设；数字方法和preliminaries。

简介：Groningen:StyxPublications,1999.ISBN9056930311.Hfl.85,-.Asthetitlemightsuggest,thesecollectedessayspurporttodiscussanddifferentiategenrefromtypeinapre-moderncontextofculturesthathavewrittenrecords.However,thisisnotthecase,forastheeditorspointoutinthealltoobriefpreface,theessayscollectedinthisvolumemayatfirstsightseemstrangeand,indeed,abaroqueassemblageofapparentlytotallyunrelatedtopics(p.vii).Theygoontoclaimthat'thereseemstobeadoubleredthreadrunningthroughthismulti-colouredcloth.'Thesethreadsareidentifiedas...

简介：AbstractThe first practice of pre-implantation genetic testing (PGT) was reported more than 30 years ago. PGT, originally named preimplantation genetic screening (PGS) and pre-implantation genetic diagnosis (PGD), is now categorized as PGT for aneuploidies (PGT-A), PGT for monogenic/single-gene defects (PGT-M), and PGT for chromosomal structural rearrangements (PGT-SR). Patients with fertility issues caused by advanced maternal age, carrier status of chromosomal abnormalities, or harboring pathogenic variant(s) are recommended to undergo PGT to increase the possibility of successful live birth and avoid potentially affected newborns. High-throughput techniques, such as DNA microarrays and next-generation sequencing (NGS), have enabled comprehensive screening of all 24 chromosomes, instead of few loci at a time. Furthermore, as a comprehensive PGT, PGT-Plus was enabled by the rapid development of a genome-wide single-cell haplotyping technique to detect embryo aneuploidy, single-gene disorders, and chromosomal aberrations simultaneously using a single universal protocol. In addition, non-invasive approaches enable a more intact embryo during the biopsy procedure, which may avoid potential mosaicism issues at a certain scale by testing spent culture media (SCM). As a novel PGT application, PGT-P detects genome-wide variations in polygenic diseases, which account for a large proportion of premature human deaths and affect a markedly larger population than monogenic diseases, using polygenic risk score calculation to decrease the potential of affecting complex conditions. Owing to the emergence of new technologies recruited to PGTs, more couples with infertility issues have a promising chance of conceiving a healthy baby, ultimately facilitating the human species to live more prosper.

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简介：新经济作为助推经济转型发展的新引擎，正在不断改造和提升传统动能，释放新的动力和活力。时下大热的独角兽企业，通过其自身的爆发式增长，正引领着我国新经济的发展。

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简介：Chinawillfaceareboundofgeneticallytransmitteddiseasesinnewbornsinthreetofiveyearsifthetrendofrapidlydecliningpre-maritalphysicalexaminationsisnotreversed,accordingtoGuXiulian,ViceChairmanoftheStandingCommitteeoftheNationalPeople'sCongress.

简介：Adaptix是软件定义的OFDMA无线移动宽带接入技术的提供商，是NY3G合作伙伴，在纽约市拥有宽带无线业务（BRS）频率许可证，该公司宣布进行宽带固定和移动OFDMA／TDD的Pie-WiMAX系统的试验。

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简介：目的探讨乙型肝炎病毒pre—S1Ag、pre—S2Ag、HBV—DNA、HBV—M的相关性及其临床意义。方法HBV—DNA采用荧光定量PCR法；HBV—M及pre—S1Ag、pre—S2Ag采用ELISA法，检测96例HBV—DNA阳性感染者血清中pre-S1Ag、pre—S2Ag、HBV—M，同时以30例HBV—M全阴性的健康体检者血清作为对照，并对结果进行统计学分析。结果96例HBV—DNA阳性患者中HBsAg、HBeAg、HBcAb阳性检出率为64．6％；HBsAg、HBeAb、HBcAb阳性检出率为20．8％；HBsAg、HBcAb阳性栓出率为14．6％；pre—S1Ag在96例HBV—DNA阳性标本中检出率为70．8％；pre—S2Ag检出率为79．2％；均明显高于HBeAg的阳性率64．6％，30例对照中未检测出pre—S1Ag、pre—S2Ag及HBV—DNA。结论HBeAg、HBV—DNA、pre—S1Ag、pre—S2Ag之间具有一定的关联性。pre—S1Ag和pre—S2Ag均较HBeAg敏感。pre—S1Ag与pre—S2Ag的栓出率差异无显著性，ELISA检测HBV—M、pre—S2Ag及pre—S1Ag只是表型指标，只能提供HBV感染的间接证据。而HBV—DNA的检测是HBV感染与否的直接证据。HBV—M、pre—S1Ag、pre—S2Ag、HBV—DNA的检测各自有其独特的临床意义。应用pre—S1Ag、pre—S2Ag、HBV—DNA及HBV—M进行联合检测，对HBV感染的早期诊断，了解HBV复制、转归及监测疗效和预后有重要的意义。

简介：AbstractBackground:Viral pathogens belonging to the order Bunyavirales pose a continuous background threat to global health, but the fact remains that they are usually neglected and their distribution is still ambiguously known. We aim to map the geographical distribution of Bunyavirales viruses and assess the environmental suitability and transmission risk of major Bunyavirales viruses in China.Methods:We assembled data on all Bunyavirales viruses detected in humans, animals and vectors from multiple sources, to update distribution maps of them across China. In addition, we predicted environmental suitability at the 10 km × 10 km pixel level by applying boosted regression tree models for two important Bunyavirales viruses, including Crimean-Congo hemorrhagic fever virus (CCHFV) and Rift Valley fever virus (RVFV). Based on model-projected risks and air travel volume, the imported risk of RVFV was also estimated from its endemic areas to the cities in China.Results:Here we mapped all 89 species of Bunyavirales viruses in China from January 1951 to June 2021. Nineteen viruses were shown to infect humans, including ten species first reported as human infections. A total of 447,848 cases infected with Bunyavirales viruses were reported, and hantaviruses, Dabie bandavirus and Crimean-Congo hemorrhagic fever virus (CCHFV) had the severest disease burden. Model-predicted maps showed that Xinjiang and southwestern Yunnan had the highest environmental suitability for CCHFV occurrence, mainly related to Hyalomma asiaticum presence, while southern China had the highest environmental suitability for Rift Valley fever virus (RVFV) transmission all year round, mainly driven by livestock density, mean precipitation in the previous month. We further identified three cities including Guangzhou, Beijing and Shanghai, with the highest imported risk of RVFV potentially from Egypt, South Africa, Saudi Arabia and Kenya.Conclusions:A variety of Bunyavirales viruses are widely distributed in China, and the two major neglected Bunyavirales viruses including CCHFV and RVFV, both have the potential for outbreaks in local areas of China. Our study can help to promote the understanding of risk distribution and disease burden of Bunyavirales viruses in China, and the risk maps of CCHFV and RVFV occurrence are crucial to the targeted surveillance and control, especially in seasons and locations at high risk.

简介：WeanalyzethreeoneparameterfamiliesofapproximationsandshowthattheyaresympecticinLargrangiansenceandcanberelatedtosymplecticschemesinHamiltoniansensebydifferentsymplecticmapping.WealsogiveadirectgeneralizationofVeselovvariationalprinciplcforconstructionofschemeofhigherorderdifferentialequations.Atlast,wepresentnumericalexperiments.