简介:摘要目的探讨精细化个体化碘131治疗甲亢(GD)的临床效果。方法本研究分析了2001年12月至2006年12月期间治疗满3年的124例碘131治疗及74例ATD治疗的甲亢患者资料,并对治疗效果、体征改善、甲状腺功能检验指标变化、甲状腺质量减轻等方面作了对照。结果①体征改善碘131及ATD治疗后,两组患者多汗、手抖、胫前黏液性水肿等体征均有明显改善,突眼也有不同程度改善,两组比较差异无显著性,p>0.05;甲状腺肿大Ⅱ°以上肿大者两组均有改善,但碘治疗显著优于ATD治疗组,两组比较差异有显著性,p<0.05。②甲状腺功能检验指标TSH、FT3、FT4治疗前后比较,两组均有改善,差别均有显著性,P<0.01。TGAb、TMAb则无显著性差异,P>0.05。③甲状腺质量从治疗3月起,碘治疗组较ATD治疗组能显著减轻甲状腺质量,p<0.01,两组有显著性差异。④治愈率碘治疗组治愈率82.3%(102/124),无效3.2%(4/124);ATD治疗组治愈率71.60%(53/74),无效5.40%(4/74)。两组间比较P>0.05,治疗效果差异无显著性。⑤甲减发生率碘治疗组总的暂时甲减发生率9.7%,永久甲减发生率15.3%;ATD治疗组暂时甲减发生率23.0%,永久甲减发生率5.4%。碘治疗组永久甲减高于ATD治疗组,自治疗后6月起,两组比较p<0.01,有显著差异。⑥甲亢复发率碘治疗组复发4.0%(5/124),ATD21.6%(16/74),p<0.01,有显著差异。结论碘131与ATD治疗一样,可明显改善甲亢患者多汗、手抖、胫前黏液性水肿等体征,突眼也有不同程度改善,两组比较差异无显著性;碘治疗在服药方式上(只服一次药)、缩小Ⅱ°以上肿大的甲状腺肿、降低TSH、FT3、FT4等甲状腺功能指标、减少暂时甲减、减少甲亢复发率方面显著优于ATD治疗组。但碘治疗也有不足,永久甲减发生率高于ATD治疗组。
简介:Thesolutionreactionmechanisms,composition,donoratoms,propertiesofcoordinatelinkandstabilityofthecomplexesonthesystemsofadrenalinewithNa3+,Gd3+andTm3+havebeenstudiedbypH-potentiometrictitrationandelectronicspectroscopy.Adrenalineperturbsthef-felectronictransitionofNd3+andTm3+sothattheabsorptionspectraoftheircomplexesareshiftedtowardlongerwavelengths.Theabsorptionspectraofthecomplexesformedbythethreef-blockelementionswithadrenalineareshiftedtowardshorterwavelengthswiththeincreaseofPHinΔγ=350~650nm
简介:Mg-12Gd-2Er-1Zn-0.6Zr(wt%)合金的机械性质上的homogenization和等温的老化处理的效果被调查。猛抛的长时期的叠顺序(LPSO)结构和调节合金的变老的降水顺序分别地被观察并且分析。结果显示14H-LPSO结构在等温的老化过程以后发生在homogenization处理和阶段形式以后。这二个独立过程能被降水温度范围控制。在homogenization处理以后的当演员组合金的延伸的重要增加被归因于粗糙的主要Mg5(Gd,的消失嗯,Zn)阶段和14H-LPSO结构的存在。调查合金的降水顺序是-Mg(SSS)/(D019)/(cbco)/。而且,张力的力量(YTS)和最终的张力的力量(UTS)等温的老化合金珍视的收益有大改进,它能被归因于猛抛的阶段的高密度。图形的AbstractWith延长的变老的时间,阶段在合金被猛抛。14H-LPSO结构和阶段在498K为84h在老化以后在合金共存。14H-LPSO的层结构显然被观察[11\(\overline{2}\)0]Mg方向,它在高分辨率的传播电子显微镜学(HRTEM)被显示出图象。14H类型结构与c的一个时期显示一份叠的订单?=?3.67?nm,它不在等温的老化过程期间变化。
简介:摘要:GD包装机组的应急电源开关采用的是机械连杆式断路器的操作方式,需手动分、合闸。因配电柜门的频繁开启和机械连杆长期磨损造成的变形和错位,机械装置动作容易不到位,引起断路器不能正常通断。应急电源开关出现不灵活时需要对应急电源开关进行手动操作,存在安全隐患。
简介:摘要:GD包装机是烟草行业目前的主力机型,其传动部件是采用润滑油对推杆、轴套及滑块进行润滑,对箱体内外密封采用的是油封,但一个油封的密封效果较差,推杆推出传动箱体时带出的油膜无法完全回到传动箱体内部,润滑油在箱体外部留存,形成油滴滴落到设备上甚至烟包上形成“油污烟包”。因此我们计划对原机双推杆箱体进行改造,在箱体上增加两个油封,将双推杆带出的油膜阻断在箱体内,从而避免漏油现象的发生,杜绝了油污烟包。
简介:Whitebody-color(Y,Gd)BxV1-xO4-x:Eu3+phosphorswerepreparedbycoprecipitationreaction.UnderVUVexcitationat147nm,theredemissioncolorimetricpurityof(Y,Gd)BxV1-xO4-x:Eu3+phosphorismuchbetterthanthatofcommercialPDP(plasmadisplaypanels)phosphor(Y,Gd)BO3:Eu3+.Butitsrelativeemissionintensityisonlyabout90%ofthecommercialphosphor.
简介:Postauricalinjectionoftherapeuticswasrecentlyappliedinclinicalpracticetotreatinnereardiseasesbasedonsupposedexistenceofadirectchannelfromthepostauricalareatotheinnerear.Doubtingontheassociatedreportsandaimingtoprovideevidenceontheinnerearuptakemechanism,thepresentstudytrackedthedynamicdistributionofgadolinium-tetra-azacyclo-dodecane-tetra-aceticacid(Gd-DOTA)inratinnerearsafterpostauricalinjectionusingMRI.Atargetedtympanicmedialwalldeliverywasutilizedascontrol.Theresultsshowedthat,attheearlytimepointsafterpostauricalinjection,Gd-DOTAdistributedmainlyintissuessurroundingthebulla,temporalboneandskullandneckspace.Intheinnerear,therewasgradualuptakeofGd-DOTAonboththeipsilateralandcontralateralsideswithequalsignalintensities.Therewasnosignofdirectchannelcarryingtheagentfromthepostauricalareatotheinnerear.TargetedtympanicmedialwalldeliveryinducedsignificantlygreateruptakeofGd-DOTAintheinnerearthandidpostauricalinjection.At30minpost-administration,targetedtympanicmedialwalldeliveryyielded4.6-foldshighersignalintensitythandidpostauricalinjection.ThetotaldoseofGd-DOTAdeliveredbythetargetedtympanicmedialwallapproachwasonly0.1%ofthatdeliveredbypostauricalinjection.Inconclusion,postauricalinjectionisasystemicadministration,whichissimilartohypodermicinjection,ratherthanafocaldeliverymethod.Bycontraries,targetedtympanicmedialwalldeliveryinducesfastandabundantuptakeofGd-DOTAintheipsilateralinnerearwithoutsignificantdistributioninunwantedareas.
简介:Todevelopanewmagnesiumalloywithexcellentformabilityatroomtemperature,theeffectofY,Ce,andGdadditionontextureandstretchformabilityofMg–1.5Znalloyswascarriedout.TheresultshowsthatY,Ce,andGdadditioninMg–1.5Znalloyscaneffectivelyweakenandmodifythebasalplanetexture,characterizedbyTD-splittextureinwhichthepositionofbasalistitledfromnormaldirection(ND)towardtransversedirection(TD).WhenMg–1.5ZnalloywithGdadditionappearslowtextureintensityandTD-splittexture,wherethepositionofbasalpolesistiltedbyabout±35°fromNDtowardtoTD,thelargestErichsenvalueof7.0andtheelongationratereaches29.1%inTDdirection.However,YandCeadditioninMg–1.5Znalloyspromotealargenumberofsecondphaseparticles,whichcancelthecontributionoftheuniquebasaltexturetostretchformabilityandductility.
简介:FluorescenceandcofluorescencepropertiesofTb(Ⅲ)solidcomplexeswerestudiedusingpyromelliticacid(PMA)asligandandfluorescenceinertionsasdopingelements.Thecofluorescenceenhancement,aresultofligandsensitizedfluorescence,wasobservedinTb(Ⅲ)solidcomplexesdopedwithfluorescentinertionsLa(Ⅲ),Gd(Ⅲ),Ca(Ⅲ),andSr(Ⅲ).Theeffectofthetypeandcontentofdopingelementsonfluorescenceenhancementwasstudied,andoptimumconditionsweredetermined.TheresultsshowthatGd(La,Ca,Sr)hasclearcofluorescenceeffectinsolidcomplexTb-M-PMAsystem,andinpresentwork,rareearthcomplexfluorescentpowderthatemitsbrightgreenfluorescenceatultravioletexcitationwasobtained,whichhadpotentialapplicationasfluorescentanti-counterfeitink.
简介:分析了铸态和挤压态ZK60-xGd(x=0-4)合金的组织和相组成,测试了其拉伸力学性能。结果表明,随着Gd含量的增加,铸态组织逐渐细化,Mg-Zn-Gd新相逐渐增多,而MgZn2相逐渐减少直至消失,第二相趋于连续网状分布于晶界处;当Gd含量不超过2.98%时,铸态室温拉伸力学性能稍降低。经挤压比λ=40和挤压温度T=593K的挤压后,组织显著细化,平均晶粒尺寸逐渐减至ZK60-2.98Gd合金的2μm,破碎的第二相沿着挤压方向呈带状分布;挤压态的拉伸力学性能均显著提高:298和473K时的抗拉强度分别从ZK60合金的355和120MPa逐渐提高至ZK60-2.98Gd合金的380和164MPa。挤压态拉伸断口呈现典型的韧性断裂特征。