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  • 简介:AbstractBackground:China and the United States (US) ranked first and third in terms of new liver cancer cases and deaths globally in 2020. Therefore, a comprehensive assessment of trends in the incidence of primary liver cancer with four major etiological factors between China and the US during the past 30 years with age-period-cohort (APC) analyses is warranted.Methods:Data were obtained from the Global Burden of Disease 2019, and period/cohort relative risks were estimated by APC modeling from 1990 to 2019.Results:In 2019, there were 211,000 new liver cancer cases in China and 28,000 in the US, accounting for 39.4% and 5.2% of global liver cancer cases, respectively. For China, the age-standardized incidence rate (ASIR) consecutively decreased before 2005 but increased slightly since then, whereas the ASIR continuously increased in the US. Among the four etiological factors of liver cancer, the fastest reduction in incidence was observed in hepatitis B virus-related liver cancer among Chinese women, and the fastest increase was in nonalcoholic steatosis hepatitis (NASH)-related liver cancer among American men. The greatest reduction in the incidence of liver cancer was observed at the age of 53 years in Chinese men (-5.2%/year) and 33 years in Chinese women (-6.6%/year), while it peaked at 58 years old in both American men and women (4.5%/year vs. 2.8%/year). Furthermore, the period risks of alcohol- and NASH-related liver cancer among Chinese men have been elevated since 2013. Simultaneously, leveled-off period risks were observed in hepatitis C viral-related liver cancer in both American men and women.Conclusions:Currently, both viral and lifestyle factors have been and will continue to play an important role in the time trends of liver cancer in both countries. More tailored and efficient preventive strategies should be designed to target both viral and lifestyle factors to prevent and control liver cancer.

  • 标签: Alcohol use-related liver cancer China Global Burden of Disease Hepatitis Hepatitis B virus Hepatitis C Incidence Liver neoplasms Life Style Middle aged Non-alcoholic fatty liver disease United States
  • 简介:摘要:本文从英语学科核心素养的四个维度,以一节初中英语阅读课为案例,通过导入、读前、读中和读后环节设计的分析,探讨了各项活动对于培养学生核心素养的意义。

  • 标签: 阅读教学 教学设计 核心素养
  • 简介:Treeimprovementprogramsonloblollypine(Pinustaeda)inthesoutheasternUSAhasfocusedprimarilyonimprovinggrowth,form,anddiseasetolerance.However,duetotherecentreductionofdesignvaluesforvisuallygradedsouthernyellowpinelumber(includingloblollypine),attentionhasbeendrawntothematerialqualityofgeneticallyimprovedloblollypine.Inthisstudy,weusedthetime-of-flight(TOF)acoustictooltoassesstheeffectofgeneticfamiliesondiameter,slenderness,fiberlength,microfibrilangle(MFA),velocityanddynamicstiffnessestimatedusinggreendensity(DMOEG)andbasicdensity(DMOEB)of14-year-oldloblollypinestandsselectedfromtwosites.Allthe184and204treesoftheselectedeighthalf-sibgeneticfamiliesonsites1and2respectivelyweretestedusingTOFacoustictool,andtwo5mmcoresamplestakenatbreastheightlevel(1.3m)usedtofortheanatomicalandphysicalpropertiesanalysis.TheresultsindicatedasignificantpositivelinearrelationshipbetweendynamicMOEs(DMOEGandDMOEB)versustreediameter,slenderness,andfiberlengthwhiledynamicMOEsnegativelybutnonsignificantcorrelatedwithMFA.WhiletherewasnosignificantdifferenceinDMOEBbetweensites;velocity2forsite1wassignificantlyhigherthansite2butDMOEGwashigherforsite2thansite1.Again,themeanDMOEGandDMOEBreportedinthepresentstudypresentsasnapshotoftheexpectedstaticMOEforgreenand12%moistureconditionsrespectivelyforloblollypine.Furthermore,thereweresignificantdifferencesbetweenfamiliesformostofthetraitsmeasuredandthissuggeststhatforestmanagershavetheopportunitytoselectfamiliesthatexhibitthedesiredfibermorphologyforfinalproductperformance.Lastly,sincethedynamicMOEbasedongreendensity(DMOEG),basicdensity(DMOEB)andvelocity2presentdifferenceconclusions,practitionersofthistypeofacoustictechniqueshouldtakecarewhenextrapolatingresultsacrossthesites.

  • 标签: Genetic families Loblolly PINE Time-offlight Resonance-based
  • 简介:ThisarticleverifiedthattheTustatementionedintheoracleinscriptionswastheXiapeopleaftertheXiaDynastyhadbeenconqueredbyTang,thefirstkingoftheShangDynastymc.a.16thcenturyB.C.ThestateofXia,whichoriginatedfromYu,wasentitled"XiaHou";itskingwashencecalled"XiaHouDi"(EmperorofXiaHou),e.g."XiaHouDiQi".TheXiapeople,togetherwiththeYin(Shang)people,andtheZhoupeople,weretheso-called"peopleofSanDai"(ThreeDynasties).Asmentionedin"Lunyu,Bayi",theyfoundedthestates,withtheXiapeoplebeingassociatedwiththepine,theYinpeoplewiththecypress,andtheZhoupeoplewiththechestnut.

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  • 简介:Ba1.0Co0.7Fe0.2Nb0.1O3-δ(BCFN)oxidewithperovskitecubicstructurewassynthesizedbysolidstatereactionmethod.CO2corrosionofBCFNmembranewasinvestigatedbyX-raydiffraction(XRD),scanningelectronmicroscopy(SEM),diffusereflectanceinfraredFouriertransformedspectroscopy(DRIFT)andX-rayabsorptionfinestructurespectroscopy(XAFS).Cobalt(Co)K-edgeabsorptionspectraofBCFNannealedinCO2revealthattheoxidationstatesofCoinallthesampleswerelargerthan+3andtheydecreasedwiththeincreaseofcalcinationtime.At800℃,1%CO2introducedintoHecouldspeedupthereductionofCocationsincomparisonwithpureHe.Inaddition,sulfateionsinthebulkofBCFNmembranepreferredtomigratetothesurfaceunderCO2calcinationandformmonoclinicBa(CO3)0.9(SO4)0.1besidesorthorhombicwitherite.Moreover,SEMresultsindicatethatthenucleationandgrowthofcarbonatesgrainsstartedatthegrainboundaryofthemembrane.

  • 标签: 钙钛矿型氧化物 CO2 氧化态 组织演变 退火 X射线吸收精细结构