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  • 简介:AbstractBiobanking facilities are well established in high-income settings, where substantial funding has been invested in infrastructure. In contrast, such facilities are much less developed in resource-restricted settings. However, low-and middle-income countries (LMICs) still face a disproportionately high infectious diseases burden. Thus, the further development of infrastructure facilities, including biobanks is warranted as an important component of this unfolding clinical research environment. This perspective manuscript summarises the challenges and enablers for biobanking in LMICs, with a particular focus on infectious diseases, incorporating some of the lessons learned from the recent coronavirus disease 2019 (COVID-19) pandemic.

  • 标签: Biobanking Research infrastructures Infectious diseases Low-and-middle income countries LMICs
  • 简介:敌人版本假设建议那异国情调的种能由在他们的新奇环境逃离食肉动物和寄生虫变得侵略。Agrawal等。(敌人版本?有同种的植物对的一个实验并且多样未葬、地下敌人。生态学,86,29792989)建议在哪个介绍种类的损坏是低的区域或时间为本国的产地的侵略提供机会。我们测试了装饰背景是否可以为树和灌木向区域提供herbivory的底层,潜在地便于侵略成功。首先,我们在辛辛那提在装饰、自然的背景在本国、异国情调的种类之中比较了叶herbivory的层次,俄亥俄,美国。在第二研究,我们比较了herbivory的层次为侵略并且noninvasive在自然、装饰的背景之间的异国情调的种类。我们比为本国的种类为异国情调的种类发现了叶损坏的底层;然而,我们发现在叶损坏的数量的差别都没在装饰或自然的背景受苦。我们的结果不提供装饰背景为异国情调的植物种类从herbivory负担得起另外的版本的任何证据。

  • 标签: 自然栖息地 原生植物 观赏性 设置 入侵 取食
  • 简介:1.IntroductionThearticlebyFinkandHouston1inthisspecialissueofJournalofSportandHealthScienceprovidesanexcellentexampleofimplementinganevidence-basedfallpreventionprograminrealcommunitieswithdiverseculturesofelderlypopulations.Althoughpreliminary,theprojectrevealedanumberofinterconnectedbarriersandfacilitatorsthatshedlightonpracticalimplications("lessonslearned")forpolicymakersandprogramprovidersregardingimplementationofanyevidence-basedintervention.WhileapplaudingFinkandHouston'seffort,inthiscommentaryweshareourexperienceswithTaiJiQuan:MovingforBetterBalance(TJQMBB)2inthestateofMaryland,withadiscussionofourownsetoflessonslearnedintermsofsuccessesandchallenges.

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  • 简介:从一个螺丝钉出版社的米饭糠蛋糕或分泌物的外观对应于在抽取过程生产的油的水平。在操作背景,油抽取水平和蛋糕外观之间的关系被学习。蛋糕特征可靠地显示期望的油恢复抽取水平。这些结论适用于两Chainat1米饭糠和parboiled米饭糠。变量是螺丝钉出版社(在从8.5~19.8r/min的五个层次的集合)和在螺丝钉和桶(在1.0和1.9厘米之间的集合)之间的相应清理距离的速度。结果证明抽取的最大的层次为米饭糠是4.17%并且8.20%为parboiled米饭糠。在最大的抽取水平,仪器连续地解除了难的蛋糕,易碎,片状,在一个方面上晴朗、擦亮却在其它上迟钝、粗糙。

  • 标签: 螺旋压力机 操作设置 提取过程 米糠油 外观 采水
  • 简介:AbstractBackground:Youzhi artificial intelligence (AI) software is the AI-assisted decision-making system for diagnosing skin tumors. The high diagnostic accuracy of Youzhi AI software was previously validated in specific datasets. The objective of this study was to compare the performance of diagnostic capacity between Youzhi AI software and dermatologists in real-world clinical settings.Methods:A total of 106 patients who underwent skin tumor resection in the Dermatology Department of China-Japan Friendship Hospital from July 2017 to June 2019 and were confirmed as skin tumors by pathological biopsy were selected. Dermoscopy and clinical images of 106 patients were diagnosed by Youzhi AI software and dermatologists at different dermoscopy diagnostic levels. The primary outcome was to compare the diagnostic accuracy of the Youzhi AI software with that of dermatologists and that measured in the laboratory using specific data sets. The secondary results included the sensitivity, specificity, positive predictive value, negative predictive value, F-measure, and Matthews correlation coefficient of Youzhi AI software in the real-world.Results:The diagnostic accuracy of Youzhi AI software in real-world clinical settings was lower than that of the laboratory data (P < 0.001). The output result of Youzhi AI software has good stability after several tests. Youzhi AI software diagnosed benign and malignant diseases by recognizing dermoscopic images and diagnosed disease types with higher diagnostic accuracy than by recognizing clinical images (P = 0.008, P = 0.016, respectively). Compared with dermatologists, Youzhi AI software was more accurate in the diagnosis of skin tumor types through the recognition of dermoscopic images (P = 0.01). By evaluating the diagnostic performance of dermatologists under different modes, the diagnostic accuracy of dermatologists in diagnosing disease types by matching dermoscopic and clinical images was significantly higher than that by identifying dermoscopic and clinical images in random sequence (P = 0.022). The diagnostic accuracy of dermatologists in the diagnosis of benign and malignant diseases by recognizing dermoscopic images was significantly higher than that by recognizing clinical images (P = 0.010).Conclusion:The diagnostic accuracy of Youzhi AI software for skin tumors in real-world clinical settings was not as high as that of using special data sets in the laboratory. However, there was no significant difference between the diagnostic capacity of Youzhi AI software and the average diagnostic capacity of dermatologists. It can provide assistant diagnostic decisions for dermatologists in the current state.

  • 标签: Artificial intelligence Skin tumor Diagnostic accuracy