简介：TheestablishmentoftheEAEUwillhavebroadstrategicimplicationsfortheEurasiancontinentandtheworld.IthashelpedRussiaconsolidateitssphereofinfluenceinthepost-Sovietspaceandstrengtheneditsroleasapoleintheworld.ItwillalsoexertawideinfluenceontheEurasianregionaleconomicstructure,thegeographicaleconomiccompetitionbetweenRussiaandtheWest,andthirdparties’influenceintheregion.

简介：TheboominuseofprivatemilitarycompaniesiscloselylinkedtotheU.S.globalstrategicblueprintaswellastothecontemporaryinclinationtowardoutsourcing,theambiguityininternationallaw,andtoday'smilitaryinsurgencies.Asnationsandseparatistgroupscontinuetheirobjectivesinsecret,thecompaniestheyhirecontributetothreatstonationalsovereignty,distortthecriteriaforlegalaccesstowar,violatehumanrights,hamperpredictionsforconflictoutcomes,andcreateregulatorychaos.

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简介：Inthispaper,theinfluenceofElNi?oeventontheMadden-JulianOscillation(MJO)overtheequatorialPacificisstudiedbyusingreanalysisdataandrelevantnumericalsimulationresults.ItisclearlyshownthatElNi?ocanreducetheintensityofMJO.ThekineticenergyofMJOovertheequatorialPacificisstrongerbeforetheoccurrenceoftheElNi?oevent,butitisreducedrapidlyafterElNi?oeventoutbreak,andtheweakenedMJOevencancontinuetothenextsummer.Theconvectionoverthecentral-westernPacificisweakenedinElNi?owinter.ThepositiveanomalousOLRoverthecentral-westernPacifichasoppositevariationinElNi?owintercomparingtothenon-ENSOcases.TheverticalstructureofMJOalsoaffectedbyElNi?oevent,sotheoppositedirectionfeaturesofthegeopotentialheightandthezonalwindinupperandlowerleveltropospherefortheMJOarenotremarkableintheElNi?owinterandtendtobebarotropicfeatures.ElNi?oeventalsohasaninfluenceontheeastwardpropa-gationoftheMJOtoo.DuringElNi?owinter,theeastwardpropagationoftheMJOisnotsoregularandunanimousandthereexistssomeeastwardpropagation,whichisfasterthanthatinnon-ENSOcase.DynamicanalysessuggestthatpositiveSSTA(ElNi?ocase)affectstheatmosphericthicknessovertheequatorialPacificandthentheexcitedatmosphericwave-CISKmodeisweakened,sothattheintensityofMJOisreduced;thecombiningofthebarotropicunstablemodeintheatmosphereexcitedbyexternalforcing(SSTA)andtheoriginalMJOmaybeanimportantreasonfortheMJOverticalstructuretendingtobebarotropicduringtheElNi?o.

简介：IntheapplicationofRNAitechnology,itisanessentialsteptodesignsiRNAapplicabletotargetgene.Atpresent,therearemanyresearchesandconclusionsonsiRNAdesign.ThispaperaimstotheinfluencesofmRNAsecondarystructureorsiRNAantisense-strandsecondarystructureonsiRNAsilenceefficiency.Thepaperalsodiscussestheproblemsandsetsoutfurtherinsightsintheresearch.

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简介：AIMToinvestigatetheinfluenceofprotonpumpinhibitors（PPIs）exposureonthediagnosisofHelicobacterpylori（H.pylori）gastritisandintestinalmetaplasia.METHODS：ChronicPPIuseisassociatedwithmaskingofH.pyloriinfection.PatientswithH.pyloriinfectionarepredisposedtogastricandduodenalulcers,andlong-terminfectionwiththisorganismhasbeenassociatedwithgastricmucosalatrophyandseriouslong-termcomplications,suchasgastriclymphomaandadenocarcinoma.ThreehundredpatientsdiagnosedwithgastritisbetweenJanuary2008andApril2010wereincludedinourstudy.Thecomputerizedmedicaldatabaseofthesepatientswasreviewedretrospectivelyinordertoassesswhetherthetypeofgastritisdiagnosed（H.pylorivsnon-H.pylorigastritis）isinfluencedbyPPIexposure.H.pyloridensitywasgradedaslow,ifcorrespondingtomilddensityfollowingtheUpdatedSydneySystem,orhigh,ifcorrespondingtomoderateorseveredensitiesintheUpdatedSydneySystem.RESULTS：Patientswereequallydistributedbetweenmalesandfemaleswithamedianageatthetimeofdiagnosisof50yearsold（range：20-87）.ThehistologicaltypesofgastritiswereclassifiedasH.pylorigastritis（n=156,52%）andnon-H.pylorigastritis（n=144,48%）.Allpatientswithnon-H.pylorigastritishadinactivechronicgastritis.PatientswithnopreviousPPIexposureweremorelikelytobediagnosedwithH.pylorigastritisthanthosewithpreviousPPIexposure（71%vs34.2%,P〈0.001）.Intestinalmetaplasiawasmorelikelytobedetectedinthelatterpatients（1.4%vs6.5%,P=0.023）.MultivariateanalysishasalsodemonstratedthatinthepresenceofpreviousPPIexposure（OR=0.217,95%CI：0.123-0.385）,GERD（OR=0.317,95%CI：0.132-0.763,P=0.01）,alcoholintake（OR=0.396,95%CI：0.195-0.804,P=0.01）,thedetectionofH.pyloriwaslesslikely.ChronicuseofPPIsmaymaskH.pyloriinfectionspromotingthediagnosisofnon-H.pylorigastritisandleadstoasi

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简介：Thermalstresscaninducebirefringenceinalasermedium,whichcancausedepolarizationofthelaser.Thedepolarizationeffectwillbeverysevereinahigh-average-powerlaser.Becausethedepolarizationwillmakethefrequencydoublingefficiencydecline,itshouldbecompensated.Inthispaper,thethermalcharacteristicsoftwokindsofmaterialsareanalyzedinrespectoftemperature,thermaldeformationandthermalstress.Thedepolarizationresultfromthermalstresswassimulated.Depolarizationonnon-uniformpumpingwasalsosimulated,andthecompensationmethodisdiscussed.

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简介：AIM:Tocomparetheconjunctivalepithelialtoxicitiesofthreenewer-generationfluoroquinoloneswithoutpreservatives.·METHODS:Inaprospective,randomized,doubleblindcomparativestudy,47eyesof47patientswithaprimarypterygiumwereenrolled,anddividedrandomlyintothreegroups(levofloxacin0.5%,gatifloxacin0.3%,andmoxifloxacin0.5%).Afterpterygiumsurgerywiththesameconjunctivalautografttechnique,eachpatientmaintainedaregimenwitharandomlyassignedfluoroquinoloneeyedrop.Patientswereexaminedeveryotherdayaftersurgeryuntiltheepitheliumhadcompletelyhealed.Photosweretakenandusedtomeasuretheareaofresidualepithelialdefects.Conjunctivalhealingtimeandspeed(initialdefectarea/healingtime(mm~2/d)comparedineachgroupusingKruskal-Wallistests.·RESULTS:Therewerenosignificantdifferencesinmeanage,gender,andconjunctivaldefectsizeofthedonorsitebetweenthesegroups.However,themeanofconjunctivalhealingtimeandspeedwerestatisticallydifferentineachgroup.Themeanofconjunctivalepithelialhealingtimewas8.93±2.69d(levofloxacingroup),10.31±2.96d(gatifloxacingroup),and13.50±4.10d(moxifloxacingroup),P=0.006.Themeanconjuctivalepithelialhealingspeedwas6.18±1.39mm~2/d(levofloxacingroup),5.52±1.68mm~2/d(gatifloxacingroup),and4.40±1.30mm~2/d(moxifloxacingroup),P=0.003.·CONCLUSION:Withouttheinfluenceofpreservatives,levofloxacinandgatifloxacinmightbelesstoxictotheregenerationofconjunctivalepithelialcellsandcauseafasterconjunctivalwoundhealingrelativetomoxifloxacin.

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简介：Theeffectofparticlesizedistributionofaluminahasbeeninvestigatedforsilica-freetabularaluminalowcementcastables(LCC).Threedifferentcombinationsofaluminahavebeenincludedinthematrixformulationofthecastables.Allthethreecombinationsarecomposedofabimodalreactivealuminaandafinegroundmonomodalreactivealumina.ThefirstA1andsecondA2combinationsarerespectivelycomposedofbimodalandmonomodalaluminasfromAlteo,withadifferentfine/coarseparticlesratioforthebimodalalumina.ThetwoAlteocombinationshavebeencomparedwithathirdcombinationCcomposedofabimodalcommerciallyavailablegradeandamonomodalcommerciallyavailablegrade.OptimizationofparticlesizepackinghasbeenperformedforthethreedifferentformulationsusingtheDingerandFunkmodel.Withthisoptimization,thetwoformulationsbasedonAlteomaterial(PFR,PBRandPFR40)achievethesamelevelofperformanceinapplicativetests(flowability,coldphysicalproperties,mechanicalresistance,crystallinephases,thermalshocksandcorrosion)asreferencesolutionsonthemarket.

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简介：Thedielectricbarrierdischarge(DBD)intheglowregimeinneonhasbeeninvestigatedbyexperimentandtwo-dimensional(2D)fluidmodeling.ThedischargewascarriedoutinaplanarDBDsystemwithsegmented-electrodesdrivenbysquare-wavevoltage.TheresultsshowthattheglowDBDoriginatesinthecenteroftheelectrodeandexpandsoutwardtotheelectrodeedgeduringeachhalfcycleofthevoltage,formingaradialstructure.Thedischargedecaysfirstlyintheinnerareabutsustainslongerintheedgearea,showingareverseddischargearea.Thedischargecannotcompletelycovertheentireelectrodesurface,butremainsaborderofnon-orweakdischarge.Thefluidmodelingshowsasimilarresultinagreementwiththeexperiments.Thesimulationsindicatethattheelectricfieldintheedgeareaisdistortedduetotheboundaryeffectsothattheelectricfieldandchargedistributionaredifferentfromthatintheinnerpart.Thedistortedfieldreducesthelongitudinalcomponentneartheedgeandcausesthelocalfieldtobelowerthanthatinthecenter,andhencemakesthedischargebehindhand.Italsoinducesatransversefieldthatmakesthedischargeextendradiallyoutwardtotheedge.TheboundaryeffectplaysanimportantroleintheglowDBDstructure.