简介:在激光,微波和类似的技术的进展导致了包含皮组织的热治疗的最近的开发。这些处理的有效性被管理由联合了影响织物的热、机械、生物、神经的回答:一个有利相互作用相对小的疼痛和没有持续副作用地导致一个过程。当前,尽管每个行为的方面到建立并且理解的某个程度,任何一个都不在学科交差的区域存在到日期。一条高度学科交差的途径为学习皮肤的biothermomechanical行为被要求,包含简历热转移,简历力学和生理学。对这个题目恰当的全面文学评论在这篇论文被介绍,盖住四个题目区域:(a)皮肤结构,(b)皮肤简历热转移和热损坏,(c)皮肤简历力学,和(d)皮肤biothermomechanics。为进一步的研究的主要问题,问题,和话题也被构画出。这评论发现在每这些方面的重要进展在最近的年里被完成了。尽管焦点被放在皮肤织物的biothermomechanical行为之上,在这篇论文考察的基本概念和方法论可能也为学习另外的软纸巾是适用的。
简介:AbstractAs human life expectancy continues to increase and the birth rate continues to decline, the phenomenon of aging is becoming more prominent worldwide. Therefore, addressing the problems associated with global aging has become a current research focus. The main manifestations of human aging are structural degeneration and functional decline of aging tissues and organs, quality of life decline, decreased ability to resist diseases, and high incidence rates of a variety of senile degenerative diseases. Thus far, no ideal treatments have been found. Stem cell (SC) therapies have broad application prospects in the field of regenerative medicine due to the inherent biological characteristics of SCs, such as their plasticity, self-renewal, and multidirectional differentiation potential. Thus, SCs could delay or even reverse aging. This manuscript reviews the causes of human aging, the biological characteristics of SCs, and research progress on age reversal.
简介:and Quarterly Journal of Economics).[5] The median age of authors in the 1980s and 1990s was 36. Scholars over age 50 when their studies are published are a minute fraction of all authors in these journals. Creative economics at the highest levels is mainly for the young. That is as true in the 1990s as it was in the 1960s,The evidence in section I documents the decline in productivity at the sample means. Information on the age-productivity relationship at the extremes of the sample is interesting in its own right and might help shed some light on the possible causes of the apparent decline in productivity with age. The simplest test compares productivity losses among the top early performers with that of the entire sample of economists at elite institutions. Among the top 10% of early producers the mean values of I1,Abstract--Economists' productivity over their careers and as measured by publication in leading journals declines very sharply with age. There is no difference by age in the probability that an article submitted to a leading journal will be accepted. Rates of declining productivity are no greater among the very top publishers than among others
简介:Whereasmuchhasbeenlearnedaboutage-relatedauditorychangesintheinnerear,relativelylittleisknownabouttheagingeffectsonthevestibularpartoftheinnerear-theperipheralvestibularsystem.Herewereviewrelevantliteraturewithregardtotheprevalenceofvestibulardysfunction,vestibularfunctionalandstructuralchangesintheelderly.Theprevalenceofvestibulardysfunctionincreaseswithage.Functionally,asageincreases,VEMPamplitudesdecrease,VEMPthresholdsincrease,VORgainofHITdecreases.Duetothecomplexityofthevestibularsystem,variationsinsubjectageandmeasurementtechniques,findingsinVEMPlatencyandcalorictestsareconflicting.Toaddressthis,adirectmeasureoftheperipheralvestibularsystemshouldbeapplied.Structurally,age-relatedlossinvestibularganglionandotoconiahavebeennoted;haircellchangesarenotwelldefined;whilesubcellularchangesremaintobeexplored.Defininghowtheonsetofvestibulardysfunctioncorrelateswithstructuraldegenerationwillofferinsightsintothemechanismsunderlyingvestibularaging.
简介:and Quarterly Journal of Economics).[5 The median age of authors in the 1980s and 1990s was 36. Scholars over age 50 when their studies are published are a minute fraction of all authors in these journals. Creative economics at the highest levels is mainly for the young. That is as true in the 1990s as it was in the 1960s,The evidence in section I documents the decline in productivity at the sample means. Information on the age-productivity relationship at the extremes of the sample is interesting in its own right and might help shed some light on the possible causes of the apparent decline in productivity with age. The simplest test compares productivity losses among the top early performers with that of the entire sample of economists at elite institutions. Among the top 10%26#37,the decline appears to be quite substantial. Between years 9-10 and 14-15 elite economists as a group lose 29 to 32%26#37
简介:Agingisamultifactorialprocesscharacterizedbydeteriorationsoffunctionalcapacityofvariousorgansandthewholebodyperformance.Exogenousmechanismforagingincludesonsetandprogressofvariousdegenerativediseases,whereasintrinsicmechanismisgovernedbycellulareventswhereincatabolicprocessesexceedthecapacityforrepairandrejuvenation.1Oxygenandnitrogencenteredreactivespecies(ROS)havebeenidentifiedtoplayakeyroleinboththeintrinsicandextrinsicdevelopmentofagingprocesses,termed"freeradicaltheoryofaging".2Duringthepasthalfofcenturymajorprogresseshavebeenmadeinboththeresearchofagingmechanismandclinicalpracticesinage-relateddiseasetreatmentandelderlycare,resultingasteadyimprovementoflongevityandanimpressiveexpansionoftheelderlypopulationamongindustrializedcountryandsomedevelopingcountries.Thistrendwilllikelygrowinthecurrentcentury.
简介:and Quarterly Journal of Economics).[5 The median age of authors in the 1980s and 1990s was 36. Scholars over age 50 when their studies are published are a minute fraction of all authors in these journals. Creative economics at the highest levels is mainly for the young. That is as true in the 1990s as it was in the 1960s,The evidence in section I documents the decline in productivity at the sample means. Information on the age-productivity relationship at the extremes of the sample is interesting in its own right and might help shed some light on the possible causes of the apparent decline in productivity with age. The simplest test compares productivity losses among the top early performers with that of the entire sample of economists at elite institutions. Among the top 10%26#37,the decline appears to be quite substantial. Between years 9-10 and 14-15 elite economists as a group lose 29 to 32%26#37
简介:Theprolongationoflifeexpectancyandthedrasticreductionoffertilityratearetheprimarycauseofanagingworld.Itisprojectedthattheelderly(above65)willincreasewithinthenext25yearsby82%,whereasthenewbornonlyby3%.Despitetheenormousmedicalprogressduringthepastfewdecades,thelastyearsoflifearestillaccompaniedbyincreasingillhealthanddisability.Theabilitytomaintainactiveandindependentlivingforaslongaspossibleisacrucialfactorforaginginhealthanddignity.Therefore,thepromotionofhealthyagingandthepreventionofdisabilityinmen,mustassumeacentralroleinmedicalresearchandmedicalpracticeaswellasintheformulationofnationalhealthandsocialpolicies.Effectiveprogramspromotinghealthandagingwillensureamoreefficientuseofhealthandsocialservicesandimprovethequalityoflifeinolderpersonsbyenablingthemtoremainindependentandproductive.Themostimportantanddrasticgenderdifferencesinagingarerelatedtoorgansandorsystemsdependantorinfluencedbyreproductivehormones.Indistinctiontothecourseofreproductiveaginginwomen,withtherapiddeclineinsexhormonesandexpressedbythecessationofmenses,agingmenexperienceaslowandcontinuousdeclineofhormones.Thisdeclineinendocrinefunctioninvolves:Adecreaseoftestosterone,dehydroepiandrosterone(DHEA),oestrogens,thyroidstimulatinghormone(TSH),growthhormone(GH),insulin-likegrowthfactor-1(IGF-1),andmelatonin.ThisdecreaseisconcomitantwithanincreaseofLHandFSH.Inadditionsexhormonebindingglobulin's(SHBG)increasewithageresultinginfurtherloweringtheconcentrationsoffreebiologicallyactiveandrogens.Interventionssuchashormonereplacementtherapymayprevent,delayoralleviatethedebilitatingconditionswhichmayresultfromsecondarypartialendocrinedeficiency.Primaryandsecondarypreventivestrategiessuchasthepromotionofasafeenvironment,healthylifestyleincludingp
简介:TasksforChina’sAgingProgrammeTheobjectivesofChina’sagingprogrammeareto“provideeconomicsupport,medicalandhealthcareservicesand...
简介:and Quarterly Journal of Economics).[5 The median age of authors in the 1980s and 1990s was 36. Scholars over age 50 when their studies are published are a minute fraction of all authors in these journals. Creative economics at the highest levels is mainly for the young. That is as true in the 1990s as it was in the 1960s,The evidence in section I documents the decline in productivity at the sample means. Information on the age-productivity relationship at the extremes of the sample is interesting in its own right and might help shed some light on the possible causes of the apparent decline in productivity with age. The simplest test compares productivity losses among the top early performers with that of the entire sample of economists at elite institutions. Among the top 10%26#37,the decline appears to be quite substantial. Between years 9-10 and 14-15 elite economists as a group lose 29 to 32%26#37
简介:ThereisuptonownoconstitutivemodelinthecurrenttheoriesofCDMthatcouldgiveadescriptionforthedegradationofagingconcrete.Thetwointernalstatevariablesβandωareintroducedinthispaper.βiscalledcohesionvariableasanadditionalkinematicparameter,reflectingthecohesionstateamongmaterialparticles.ωiscalleddamagefactorformicro-defectssuchasvoids.ThenadamagemodelandaseriesofconstitutiveequationsaredevelopedonContinuumMechanics.Themodelproposedcouldgiveavaliddescriptionforthewhole-course-degradationofagingconcreteduetochemicalandmechanicalactions.Finally,thevalidityofthemodelisevaluatedbyanexampleandexperimentalresults.