简介：AIM:Toinvestigatetheaccuracyofintraocularpressure(IOP)asmeasuredbyaReichertOcularResponseAnalyzer(ORA),aswellastherelationshipbetweencentralcornealthickness(CCT)andIOPasmeasuredbyORA,Goldmannapplanationtonometry(GAT),anddynamiccontourtonometry(DCT).·METHODS:Atotalof158healthyindividuals(296eyes)werechosenrandomlyformeasurementofIOP.AfterCCTwasmeasuredusingA-ultrasound(A-US),IOPwasmeasuredbyORA,GAT,andDCTdevicesinarandomizedorder.TheIOPvaluesacquiredusingeachofthethreetonometrieswerecompared,andtherelationshipbetweenCCTandIOPvalueswereanalyzedseparately.TwoIOPvalues,Goldmann-correlatedIOPvalue(IOPg)andcorneal-compensatedintraocularpressure(IOPcc),weregotusingORA.ThreegroupsweredefinedaccordingtoCCT:1)thincornea(CCT<520μm);2)normal-thicknesscornea(CCT:520-580μm);and3)thickcornea(CCT>580μm)groups.·RESULTS:Innormalsubjects,IOPmeasurementswere14.95±2.99mmHgwithORA(IOPg),15.21±2.77mmHgwithORA(IOPcc),15.22±2.77mmHgwithGAT,and15.49±2.56mmHgwithDCT.Meandifferenceswere0.01±2.29mmHgbetweenIOPccandGAT(P>0.05)and0.28±2.20mmHgbetweenIOPccandDC(P>0.05).TherewasagreatercorrelationbetweenIOPccandDCT(r=0.946,P=0.000)thanthatbetweenIOPccandGAT(r=0.845,P=0.000).DCThadasignificantcorrelationwithGAT(r=0.854,P=0.000).GATwasmoderatelycorrelatedwithCCT(r=0.296,P<0.001),whileIOPccshowedaweakbutsignificantcorrelationwithCCT(r=0.155,P=0.007).TherewasastrongnegativecorrelationbetweenCCTandthedifferencebetweenIOPccandGAT(r=-0.803,P=0.000),withevery10increaseinCCTresultinginanincreaseinthisdifferenceof0.35mmHg.Thethickcorneagroup(CCT>580μm)showedtheleastsignificantcorrelationbetweenIOPccandGAT(r=0.859,P=0.000);whilethethincorneagroup(CCT<520μm)hadthemostsignificantcorrelationbetweenIOPccandGAT(r=0.926,P=0.000).ThecorrelateddifferencesbetweenIOPccan

简介：AIMTo与反弹tonometry(RBT)调查成年畿尼猪眼睛的intraocular压力(IOP)，并且估计包括Carteolol减少药的四特殊热门IOP的效果，Brimonidine，24头12-week-old畿尼猪(48只眼睛)的Brinzolamide和Latanoprost.METHODSTheIOP每二个小时作为基线与RBT一天内被测量。所有动物然后被划分成四个组(Carteolol，Brimonidine，Brinzolamide和Latanaprost组织，n=6)。IOP被测量并且与基线相比1，2，3，5，7，9，15并且在24头畿尼猪(48只眼睛)的treatment.RESULTSThe平均数基线IOP以后的24h是10.3GSH试金工具包。Akt1和Aktphosphorylation(p-Akt1)层次被西方的弄污测量，immunofluorescence.RESULTSAA在高集中导致了毒性并且显著地在20的集中刺激了HCEC的增长

简介：AIMTo根据国际标准组织(ISO)把IOPen和ICare反弹tonometry比作Goldmannapplanationtonometry(GAT)8612criteria.METHODSTotally，191只眼睛(n=107个人)被包括。ISO8612的标准被完成：IOP的3簇，由GAT测量了，被形成。GAT结果作为吝啬的瑡敩瑮?湵敤杲楯杮挠瑡牡捡?桰捡敯畭獬晩捩瑡潩?敷敲爠湡潤業敺?湩潴琠潷朠潲灵被给吗？