简介：Selectivelasermelting(SLM)isoneofthemostpopularadditivemanufacturing(AM)technologiesformetalparts.Slicingresult,especiallyforthedifferentdimensionalslicinggeometryanditstopology,playsanimportantrolebecauseofthethermodynamicbehaviorofmetalpowders.Togetcorrectgeometryandreliabletopology,aslicingstrategyforSLMisproposed.Theunavoidablenumericalerrorcausedbysamplingandgeometrictransformationissuppressedfirstly,accordingtoshiftingthez-coordinateofavertexwithasmallvaluesuchtheshiftedvertexisonaslicingplane.Theresultofvertex-shiftingmakesitpossibletoidentifydifferentgeometricfeaturessuchasskinsurfaces,overhangsurfaces,extremeedgesandvolumetricsolid.Second,fromgeometricprimitivesahierarchyofaxis-alignedboundingboxes(AABBs)isconstructedandusedtospeedupintersectionofslicingplanesagainstsetsoftriangles.Allintersectingsegmentsaregivendifferentsignstodepicttheirgeometricortopologicalinformation.Basedthedifferentsigns,thedifferentdimensionalgeometrythatiseventuallyrepresentedbysimpleandanticlockwiseorientedpolygons,areidentified.Finally,thepolygonsareclassifiedandnestedinamulti-treedatastructuresettoproducecorrecttopologicalrelations.Theresultofdigitalandphysicalexperimentsshowstheproposedslicingstrategyisfeasibleandrobust.

简介：在allogeneic干细胞移植(SCT)，缺乏他们的血缘的禁止的ligand的生来的杀手(NK)房间能导致graft-versus-leukemia回答，没有严重graft-versus-host疾病(GVHD)的正式就职。这个特征能为细胞的免疫疗法被利用。在这研究，我们检验了在整个人的外部血NK房间人口以内表示不同漂亮像免疫球蛋白的受体(KIR)的NK房间子集的选择扩大，面对HLA-Cw3(C1)或Cw4(C2)transfectedK562激发器房间。有C1或C2的KIR+NK房间的Coculture积极K562房间，面对IL-2+；IL-15，触发了错过了他们的血缘的ligand的NK房间的长出。这在整个NK房间人口以内导致了alloreactiveKIR+NK房间的增加的频率。在有缺乏他们的血缘的ligand的K562房间的preculture以后，当时，另外，我们观察到这张alloreactiveNK人口揭示了CD107+房间的更高的数字有相关K562HLA-Ctransfected目标房间的cocultured，作为与有untransfectedK562房间的coculture相比。这提高的反应作为目标用主要白血病的房间被证实。这研究证明那HLA一级表情能调停扭曲NK房间全部剧目并且向白血病的目标房间与提高的alloreactivity为房间充实人口。这个特征可以支持未来NK基于房间的免疫疗法的临床的应用。

简介：Graphene(GR)-CdSnanocompositeswithdifferentweightadditionratiosofGRhavebeenassembledbyafacilesolvothermaltreatment.TheGR-CdSnanocompositephotocatalystwithanappropriateratioofGRexhibitsenhancedphotoactivityforselectivereductionofaromaticnitrocompoundstothecorrespondingaromaticaminesinwaterundervisiblelightirradiationascomparedwithblank-CdS.ThecharacterizationofGR-CdSnanocompositephotocatalystsbyacollectionoftechniquesdisclosesthat:i)GRcantunethemicroscopicmorphologyofCdSnanoparticlesandimprovelightabsorptionintensityinthevisiblelightregion;ii)GRscaffoldsactasanelectronreservoirtotrapandshuttletheelectronsphotogeneratedfromCdSsemiconductorunderthevisiblelightillumination;iii)theintroductionofGRenhancestheadsorptioncapacityofGR-CdSnanocompositestowardthesubstrates,aromaticnitrocompounds.ThesynergisticeffectofthesefactorsshouldaccountforthephotoactivityadvancementofGR-CdSnanocompositestowardtheprobereactions.Furthermore,becausethephotogeneratedholesinthesystemaretrappedbythequenchingagentammoniumoxalate,theas-obtainedGR-CdSphotocatalystisstableduringthephotocatalyticreductionreactions.Areasonablemodelhasalsobeenproposedtoillustratethereactionmechanism.

简介：Femtosecond导致激光的提高回声的multiphoton电离光电子光谱学(REMPI-PS)面临二个缺点低光谱分辨率和差的选择刺激由于女人光谱带宽。我们建议一个计划获得高分辨率的选择刺激(2+1)由联合和cosinusoidal阶段调整的REMPI-PS。我们的理论结果显示(2+1)与附近的激动的状态有关的REMPI-PS信号能被阶段调整区分开来与他们的难区分的光电子系列，然后他们的选择刺激能被补加地增加cosinusoidal阶段调整认识到。而且，高分辨率的选择刺激的物理机制(2+1)REMPI-PS被考虑二光子的力量光谱解释。

简介：Molecularlyimprintedpolymers(MIPs)werepreparedbythebulkpolymerizationusingcrystalvioletasthetemplatemolecule,andthemethacrylicacidandethyleneglycoldimetheacrylateasfunctionalmonomerandcross-linker,respectively.Systematicinvestigationsofsyntheticconditionswereconducted.Thesurfacemorphologyandrecognitionmechanismoftheobtainedpolymerswerestudiedusingscanningelectronmicroscopeandspectrophotometricanalysis.MIPsshowedhighaffinitytotemplatemoleculeandweresuccessfullyappliedasspecialsolid-phaseextractionsorbentforselectiveextractionofcrystalvioletfromnaturalseawater.Anoff-linemolecularlyimprintedsolid-phaseextraction(MISPE)methodfollowedbyhigh-performanceliquidchromatographywithdiodearraydetectionfortheanalysisofcrystalvioletwasalsoestablished.MISPEcolumnshavegoodrecoveriesforcrystalvioletstandardsolutionsandgoodlinearitywasobtainedovertheconcentrationrangeof0-200μgL-1(R2>0.99).Finally,twonaturalseawatersampleswereinvestigated.TherecoveriesofspikedseawaterontheMISPEcolumnswerefrom44.47%to62.34%,therelativestandarddeviation(n=3)beingintherangeof2.89%-5.96%.