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简介：进入2004年后，腾讯一直在不遗余力地为QQ注入新的活力，经过几个月的QQ预览版后，腾讯QQ终于推出了功能更为强大的QQ2004Beta版，你可不要小看这个Beta版，它所包含的内容可一点不弱呦！

简介：1.IntrodnctionThispaperextendsthestudyofthesingularmatrixvariatebetadistributionofrank1[1]tothecaseofageneralrank.Astherelateddistributiontonormalsampling,thematrixvariatebetadistribution(alsocalledthemultivariatebetadistribution)hasbeenstudiedextens...

简介：在现在的纸，我们介绍Baskakov贝它操作员的q类似物。我们证实一些在连续函数的加权的空格在间隔上定义的多项式指导结果[0，)。然后，我们获得点明智的估计，用Lipschitz类型最大的功能。

简介：Aprobabilitydensityfunction(PDF)isderivedofbetadistributionwithbothλ3(skewness)andλ4(kurtosis)asparametersforweaklynonlinearwavesurfaceelevationbyuseofamethodrecentlyproposedbySrokosz.ThisPDFnotonlyhasasimplerformthanthewell-knownGram-CharlierSeriesPDFderivedbyLonguet-Higgins,butalsoovercomesanobviousshortcomingofthelatterthatwhentheseriesisunsuitablytruncated,theresultingPDFislocallynegative.TotestthederivedbetaPDF,laboratorialexperimentsofwindwavesareconducted.TheexperimentaldataindicatethatthetheoreticalrequirementsoftheparametersinthebetaPDFarefulfilled.TheexperimentalresultsshowthatthepresentPDFisinbetteragreementwiththemeasureddatathanthebetaPDFonlyincludingparameterλ3,andalsothantheGram-CharlierSeriesPDFtruncateduptothetermofH6.

简介：趋势科技近日在其网站上推出企业桌面安全解决方案趋势科技OfficeScan7．8beta版，该产品将随着WindowsVista的问世而为其提供防病毒和其他保护。WindowsVista是Windows客户端操作系统的下一代产品。趋势科技OfficeScan可以保护企业的WindowsVista计算机免遭病毒和恶意代码攻击，包括文件病毒、宏病毒和恶意间谍软件、JavaApplet以及ActiveX控制。面向WindowsVistabeta版的趋势科技OfficeScanbeta版是在2006年5月参加微软的技术采纳计划（TAP）最先推出的，现在可以通过趋势科技的公开网站立即下载OfficeScan7．8beta版。

简介：对于MMO这种类型的游戏来说，发行前能否获得玩家群体的支持（communitysupport）对于游戏上市后能否取得成功有着至关重要的影响。要想让你的游戏成为大家茶余饭后的焦点，一个最好的办法就是让游戏玩家群中经验丰富的成员参加到游戏的早期测试中。话虽如此，但在实际操作中，还是需要谨慎地把握好尺度。

简介：AbstractThalassemia, classified as the main types α- and β-thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β-thalassemia major in China, including its epidemiology and treatment.

简介：ObjectivesToinvestigatetheeffectsoftestosteroneenanthate(TE)onserumlipidsandlipoproteinsmetabolismandtheexpressionofandrogenreceptor(AR),estrogenreceptorbeta(ER-β)andplateletderivedgrowthfactorbeta(PDGFR-β)inaorticvascularsmoothmuscletissues(VSMTs).MethodsFortyagedmaleratswererandomlydividedinto4groups,groupA(placebogroup),groupB(2.5mg/kgintramuscularinjectionofTEonceaweek),groupC(5.0mg/kgintramuscularinjectionofTEonceaweek),groupD(10.0mg,/kgintramuscularinjectionofTEonceaweek).Allanimalswerefedfreelyduring16-weektreatmentperiods.TheexpressionofAR,ER-βandPDGFR-βwerestudiedbyWesternbolt.ResultsAverageserumLDL-CwasloweringroupDthanthatingroupA(p＜0.01).Comparedwiththeothergroups,averageserumTCwasalsoloweringroupD(p＜0.05).ARexpressioninaorticvascularsmoothmuscletissuescouldberegulatedbyTE:99.50±21.74,125.38±28.68and101.98±15.42forTEconcentrationsat2.5mg/kg,5.0mg/kgand10.0mg/kg,respectively,theexpressionofER-βcouldberegulatedbyTE:92.34±18.68,47.72±18.12,82.13±23.50,andtheexpressionofPDGFR-βcouldberegulatedaswellbyTE:219.70±45.59,50.16±9.72,125.36±15.74(DataforAR,ER-βandPDGFR-βproteinbandintensitywereexpressedwithx±s,withcontrolgrouptakenas100).ConclusionsThisstudyindicatesthatandrogenshavesignificanteffectsonserumlipidsandlipoproteinmetabolism.Testosteroneenanthateat5.0mg/kgcanstimulatetheexpressionofAR,butinhibitetheexpressionofPDGFR.Testosteroneenanthateattheconcentrationsof5.0mg/kgand10.0mg/kgcaninhibitetheexpressionofER-β.

简介：9月7日，FreeBSD项目组发布FreeBSD6．0-Beta4版。这是继7月15日发布FreeBSD6．0第一个测试版后推出的第四个Beta版本。FreeBSD6．0增加了更多无线网卡和无线安全标准支持，并且改进文件系统，支持对Linux所使用的ReiserFS文件系统进行读操作。FreeBSD项目组计划在FreeBSD6．0正式推出后，对FreeBSD开发网站进行改版。

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简介：Inthepresentpaper,weproposetheqanalogueofSza′sz-Beta-Stancuoperators.Byestimatethemoments,weestablishdirectresultsintermsofthemodulusofsmoothness.Investigatetherateofpoint-wiseconvergenceandweightedapproximationpropertiesoftheqoperators.Voronovskajatypetheoremisalsoobtained.Ourresultsgeneralizeandsupplementsomeconvergenceresultsoftheq-Sza′sz-Betaoperators,thustheyimprovetheexistingresults.

简介：一套完全免费的动态域名解析服务客户端软件。当你安装并注册该项服务，无论你在任何地点．任何时间使用任何线路，均可利用这一服务建立拥有固定域名和最大自主权的互联网主机。“花生壳”支持的线路包括普通电话线．ISDN．ADSL、有线电视网络，双绞线到户的宽带网和其它任何能够提供互联网真实IP的接入服务线路，

简介：Texturepatternmappingisoneofthemostimportanttechniquesforhighqualityimagesyn-thesis.Itcanlargelyenhancethevisualrichnessofraster-scanimages.Inthispaperispresentedanewmethodofmappingplanartexturepatternontobeta-splinecurvedsurfaces——bilinearmappingmethodwhichcanmapplanartexturepatternontocurvedsurfaceswithlessdistortion,andalsocanfulfillthegeometrictransformationofthetexturepatternonthecurvedsurfacesbyoperatingthepatternwin-dow.ItisvaluabletobothCAD/CAMinartisticfieldandcomputergraphics.

简介：AbstractBackground:Circular RNAs (circRNAs) are considered to be important regulators in cancer biology. In this study, we focused on the effect of circRNA baculoviral inhibitor of apoptosis protein (IAP) repeat containing 6 (circBIRC6) on non-small cell lung cancer (NSCLC) progression.Methods:The NSCLC and adjacent non-tumor tissues were collected at Shanghai Ninth People's Hospital. Quantitative real-time polymerase chain reaction was conducted for assessing the levels of circBIRC6, amyloid beta precursor protein binding protein 2 (APPBP2) messenger RNA (mRNA), baculoviral IAP repeat containing 6 mRNA (BIRC6), and microRNA-217 (miR-217). Western blot assay was adopted for measuring the protein levels of APPBP2, E-cadherin, N-cadherin, and vimentin. Colony formation assay, transwell assay, and flow cytometry analysis were utilized for evaluating cell colony formation, metastasis, and apoptosis. Dualluciferase reporter assay and RNA immunoprecipitation assay were carried out to determine the interaction between miR-217 and circBIRC6 and APPBP2 in NSCLC tissues. The murine xenograft model assay was used to investigate the function of circBIRC6 in tumor formation in vivo. Differences were analyzed via Student's t test or one-way analysis of variance. Pearson's correlation coefficient analysis was used to analyze linear correlation.Results:CircBIRC6 was overexpressed in NSCLC tissues and cells. Knockdown of circBIRC6 repressed the colony formation and metastasis and facilitated apoptosis of NSCLC cells in vitro and restrained tumorigenesis in vivo. Mechanically, circBIRC6 functioned as miR-217 sponge to promote APPBP2 expression in NSCLC cells. MiR-217 inhibition rescued circBIRC6 knockdown-mediated effects on NSCLC cell colony formation, metastasis, and apoptosis. Overexpression of miR-217 inhibited the malignant phenotypes of NSCLC cells, while the effects were abrogated by elevating APPBP2.Conclusion:CircBIRC6 aggravated NSCLC cell progression by elevating APPBP2 via sponging miR-217, which might provide a fresh perspective on NSCLC therapy.

简介：介绍了视频跟踪中图像边缘检测的基于Beta样条函数的边缘检测算子,该算法是利用Beta样条函数对原始图像进行拟合,然后求拟合曲面的二阶导数零交叉点来检测图像的边缘.根据Beta样条函数的局部性质得到具体卷积模板,由于它具有两个自由参数,使它比B样条边缘检测算子具有更大的灵活性.

简介：腾讯发布了QQ2009Preview3,但是因为某些功能不完全,使用QQ2008的人还是更多些,这里笔者给大家共享最新的QQ2008II的一些实用技巧,让大家在使用QQ2008中带来更多的乐趣。

简介：BACKGROUND:ToevaluateandsummarizetheeffectsofcerebralperfusionandvascularreserveonthetreatmentofSICAS.Recently,researchonβ-amyloidproteinhasfocusedontheregulatoryeffectsofes-trogenorphytoestrogenonitsdeposition.However,therehavebeenonlyafewreportsondynamicchangesofβ-amyloidproteindepositioninhippocampusofovariectomizedrats.OBJECTIVE:Tomeasureβ-amyloidproteindepositioninthehippocampalformationofovariectomizedratsbyusingimmunohistochemistry;toobservetime-dependentdynamicchanges.DESIGN:Randomizedcontrolledanimalstudy.SETTING:ThirdXiangyaHospitalofCentralSouthUniversity.MATERIALS:TheexperimentwascarriedoutintheCentralLaboratoryoftheThirdXiangyaHospitalofCentralSouthUniversityfromNovember2005toDecember2006.FiftyhealthyfemaleSpragueDawley(SD)rats,weighing(293±10)g,wereprovidedbytheAnimalLaboratoryofXiangyaMedicalCollege,CentralSouthUniversity.Allratshadneitherachildbearinghistorynorhepaticorrenaldisease,orskeletaldeformity.β-amyloidproteinimmunohistochemicalkitwasprovidedbyWuhanBosterCompany.Theex-perimentwasinaccordancewithanimalethicsstandards.METHODS:Allratswererandomlydividedintofivegroups,includingnormalcontrolgroup(n=10),shamoperationgroup(n=10),andovariectomizedgroup(n=30).Afteranesthesiaintheovariectomizedgroup,thebilateralovarieswereseparatedandresected.Thesamevolumeoffatwasresectedintheshamoperationgroup.Ratsfromthenormalcontrolgroup,however,didnotreceiveanysurgicaltreatments.Ratsinthenormalcontrolgroupandshamoperationgroupweresacrificedbyanesthesia7weeksaftersurgery.Everytenratsfromtheovariectomizedgroupwasrespectivelysacrificedat7,15,and30weeksaftersurgery.Immunohistochemistrywasusedtodetectβ-amyloidproteindepositioninhippocampalsections.Cellcountingandgrayvaluemeasurementsservedtorecordthedynamicchangesin�