简介:摘要目的探讨比较鼻内窥镜下电凝治疗恶性鼻出血与激光烧灼止血的实用性。方法对2011年以来我科收治100例病人随机分配各50例,采用鼻内窥镜下电凝治疗恶性出血与激光烧灼治疗的治疗操作时间、成功率、术中出血量进行比较。结果自2011年以来我科收治的100例病人中有50例进行电凝止血治疗,平均操作时间1-5分钟,完全成功,术中血量20-100ml平均40ml,10例患者进行激光烧灼止血失败,转为电凝止血,6例成功,成功率93%。50例患者采用激光烧灼治疗,40例治愈,操作时间平均15-20分钟,成功80%,术中血量30-200ml平均70ml。结论对恶性鼻出血的治疗鼻内窥镜下电凝近期疗效优于激光烧灼,值得临床推广应用。
简介:摘要血液净化的技术发展很快,对人类身体的健康做出了很大的贡献。有关血液净化的医学知识也被越来越多的人熟知。血液净化有多种方式,包括血液透析、血液灌流、血液滤过、血浆置换和腹膜透析等。低分子肝素的抗凝作用对血液净化的顺利进行提供了很大帮助,为了证明低分子肝素相比普通肝素更具有优势,我们选择50例患者分两组进行研究,得出了这一结论。
简介:AIM:Tofindouttheoutcomeoflaserphotocoagulationinclinicallysignificantmacularedema(CSME)byopticalcoherencetomography(OCT).·METHODS:Itwasaprospective,non-controlled,caseseriesstudyenrolling81eyesof64patientswithCSMEbetweenAugust2008andJanuary2010.AllpatientsreceivedmodifiedgridphotocoagulationwithfrequencydoubledNd:YAGlaser.Eachpatientwasevaluatedintermsofbest-correctedvisualacuity(BCVA)andregressionorprogressionofmaculopathyafterlasertherapyat1,3and6months.Spearman’scorrelationtestwasusedtoshowthecorrelationbetweenBCVAandtotalmacularvolume(TMV).Analysisofvariance(ANOVA)wasusedtocompareamonggroupsandindependentt-testwasusedtocompareineachgroup.·RESULTS:ThereishighcorrelationbetweenBCVAandTMV(P≤0.001).BCVAimprovedin50.6%,remainedstaticin39.5%anddeterioratedin9.9%patientsafter6monthoftreatment.TheBaselineTMV(meanandSD)were9.26±1.83,10.4±2.38,11.5±3.05,8.89±0.75and9.47±1.98mm3fordifferentOCTpatterns,ST(spongelikethickening),CMO(cystoidmacularedema),SFD(subfovealdetachment),VMIA(Vitreomacularinterfaceabnormality)andaverageTMVrespectively(P=0.04).After6monthsoflasertreatment,themeanTMVdecreasedfrom9.47±1.98mm3to8.77±1.31mm3(P=0.01).InSTtherewassignificantdecreaseinTMV,P=0.01,Furtherwithinthesegroupsat6months,theyweresignificantlydifferent,P=0.01.·CONCLUSION:OCTshowedthedifferentmorphologicalvariantofCSMEwhiletheresponseoftreatmentisdifferent.TMVdecreasedthemostandhenceshowedtheimprovementinvisionafter6monthsoflasertreatment.IntheeraofAntivascularendothelialgrowthfactors(VEGFs),efficacyoflaserseemstobeinshadowbutitisstillfirstlineoftreatmentindevelopingnationlikeNepalwhereantiVEGFsmaynotbeeasilyavailableandaffordable.