学科分类
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336 个结果
  • 简介:Theeffectandmechanismofcarmustine(BCNU)combinedwithall-transretinoicacid(ATRA)ontheapoptosisofhumanglioblastomaU251cellswereinvestigatedbymeansof3-(4,5-dimethylthiazol-2-yl)-2,5-diphe-nyltetrazoliumbromide(MTT)assay,flowcytometry,reversetranscription-polymerasechainreaction(RT-PCR)andWesternblotanalysis.TheresultsshowthatBCNUorATRAshowstime-anddose-dependentinhibitioneffectsonhumanglioblastomaU251cellsandthecombinationofBCNUwithATRAshowsansynergisticinhibitioneffectonhumanglioblastomaU251cells,andthecombinedBCNUandATRAcansignificantlyinhibittheproliferationofhumanglioblastomaU251cells,andinducetheapoptosisofthem,makingthecellsarrestinthestageofG1phase,thestageofSandG2phasesdecline,therateoftheapoptosisofhumanglioblastomaU251cellsincrease,thecorrespondingmRNAexpressionofcyclinEandcyclin-dependentkinase2(CDK2)downregulatedandthecorrespon-dingmRNAexpressionofp27kip1unregulated.Inaddition,thecombinedBCNUandATRAreducedtheproteinexpressionofnuclearfactorkappaB(NF-κB).Takentogether,theseresultssuggestthatthetreatmentofhumanglioblastomaU251cellswithacombinationapplicationofATRAandBCNUcanexertsynergisticeffect,thecourseofthiskindofcombinationchemotherapymaylikelybeassociatedwithmultiplemolecularmechanismsforapoptosis,furthermore,thecyclinEandp27kip1shouldbeconsideredasnoveltargetsforcontrollingthegrowthofglioblastomacells.

  • 标签: 全反式维甲酸 脑胶质瘤 细胞凋亡 细胞周期素 卡莫司汀 细胞周期蛋白依赖性激酶
  • 简介:引进分次Armendariz环的概念,讨论了分次环R=n∈ZRn及由它导出的非分次环R,R0,及R[x]之间关于Armendariz环性质的关系,并推广了[8]的结论,得到在R=n∈ZRn是Z-型正分次环的前提下,若R是分次Armendariz,分次正规环,则R是P.P.环(Baer环)当且仅当R是分次P.P.环(分次Baer环).

  • 标签: 分次Armendariz环 分次P.P.环 分次Baer环 分次正规环
  • 简介:在Г-环中定义P-根,次P-根与拟P-根的概念,讨论它们的性质及相互间的关系.给出了次P-根的构造,证明了对Г-环的任一代数性质P,总可确定两个Amitsur-Kurosh根.同时,对Г-环的几个具体根的研究做了统一.拓广了Г-环根理论的研究领域.

  • 标签: 拓广 代数性质 证明 构造 具体 研究领域
  • 简介:Multimediastreamingservedthroughpeer-to-peer(P2P)networksisboomingnowadays.However,theend-to-endstreamingqualityisgenerallyunstableduetothevariabilityofthestateofserve-peers.Ontheotherhand,proxycachingisabandwidth-efficientschemeforstreamingovertheInternet,whereasitisasubstantiallyexpensivemethodneedingdedicatedpowerfulproxyservers.Inthispaper,wepresentaP2PcooperativestreamingarchitecturecombinedwiththeadvantagesofbothP2Pnetworksandmultimediaproxycachingtechniquestoimprovethestreamingqualityofparticipatingclients.Inthisframe-work,aclientwillsimultaneouslyretrievecontentsfromtheserverandotherpeersthathaveviewedandcachedthesametitlebefore.Inthemeantime,theclientwillalsoselectivelycachetheaggregatedvideocontentsoastoservestillfutureclients.Theassociateprotocoltofacilitatethemulti-pathstreamingandadistributedutility-basedpartialcachingschemearedetailedlydis-cussed.Wedemonstratetheeffectivenessofthisproposedarchitecturethroughextensivesimulationexperimentsonlarge,Inter-net-liketopologies.

  • 标签: 分布式高速缓存 P2P网络 流媒体服务 体系结构
  • 简介:SomecharacterizationsoftheconditionalexpectationoperatorsonLebesgue-BochnerspacesL_p(μ,X)aregiven,where1≤p<∞,p≠2.AlsoanexampleisgiventoshowthatthecharacterizationsoftheconditionalexpectationoperatorsonL_p(μ,X)aredifferentfromthatonL_p(μ)_zFinally,arepresentationoftheconstant-preservingcontractiveprojectiononspacesL_p(μ,X)isgotwhen0<p<1.

  • 标签: preserving EXPECTATION OPERATORS Radon CONDITIONAL LEBESGUE
  • 简介:运用转移矩阵的技巧,本文给出了戴帽B27N27硼-氮zlgzag纳米管的克库勒结构数的计算公式.在实际计算中,根据管的对称性,转移矩阵的阶得到了显著地降低.

  • 标签: 戴帽B27N27硼-氮zigzag纳米管 克库勒数
  • 简介:ONTHECLASSφ_~*(α,β,γ,ε,η;A)ofp-VALENTFUNCTIONSWITHREFERENCETOTHEBERNARDIINTEGRALOPERATORJianMing(蹇明)(WuhanUniversity,Wuhan430...

  • 标签: CLASS OPERATOR THEBERNARDI ON FUNCTIONS INTEGRAL
  • 简介:<正>LetD={z∈:|z|<1}andφbeanormalfunctionon[0,1).Forp∈(0,1)suchafunctionφisusedtodefineaBergmanspaceA~p(φ)onDwithweightφ~p(|·|)/(1-|·|~2).Inthispaper,thedualspaceofA~p(φ)isgiven,fourcharacteristicsofCarlesonmeasureonA~p(φ)areobtained.Moreover,asanapplication,threesequenceinterpolationtheoremsinA~p(φ)arederived.

  • 标签:
  • 简介:Letp(z)=beapolynomialdegreenandletThenaccord-ingtoBernstein’sinequality||p’||p||.ItisawellknownopenproblemtoobtaininequalityanalogoustoBernstein’sinequalityfortheclassIInofpolynomialssatisfyingp(z)≡znp(1/z)HereweobtainaninequalityanalogoustoBernstein’sinequalityforasubclassofIInOurresultsincludeseveraloftheknownresultsasspecialcases.

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  • 简介:当branes的二栈是到对方的没放的平行时,我们概括在branes的二平行的栈之间的远程的相互作用的计算到各种各样的案例。我们分类相互作用的性质(排斥或吸引人)为每个专辑,大小写和这个分类能被用来认为在象brane界限状态那样的二个复杂brane系统之间的远程的相互作用的性质正当。我们将在这份报纸提供明确的例子表明这。

  • 标签: 相互作用 长距离 分类 堆栈 吸引力 排斥力
  • 简介:InthispaperwestudytheconvergencenfaclassofmeansonHp(G)(0<p<1),themeanstaketheBochner-Rieszmeansin[1],thegeneralizedBochner-Rieszmeansin[2],andtheoperatorsTΦrin[3]asspecialcases.Weobtainweak-typeestimatesfortheassociatedmaximaloperatorsandthemaximalmeanboundednessforthemeans.

  • 标签: operators maximal RIESZ CLASS estimates singular
  • 简介:P2Psystemsarecategorizedintotree-basedandmesh-basedsystemsaccordingtotheirtopologies.Mesh-basedsystemsareconsideredmoresuitableforlarge-scaleInternetapplications,butrequireoptimizationonlatencyissue.Thispaperproposesacontentsubscribingmechanism(CSM)toeliminateunnecessarytimedelaysduringdatarelaying.Anodecansendcontentdatatoitsneighborsassoonasitreceivesthedatasegment.Noadditionaltimeistakenduringtheinteractivestagespriortodatasegmenttransmissionofstreamingcontent.CSMconsistsofthreesteps.First,everynoderecordsitshistoricalsegmentslatency,andadoptsgammadistribution,whichpossessespowerfulexpressionability,toexpresslatencystatistics.Second,anodepredictssubscribingsuccessratioofeveryneighborbycomparingthegammadistributionparametersofthenodeanditsneighborsbeforeselectinganeighbornodetosubscribeadatasegment.Theabovestepswouldnotincreaselatencyastheyareexecutedbeforethedatasegmentsarereadyattheneighbornodes.Finally,thenode,whichwassubscribedto,sendsthesubscribeddatasegmenttothesubscriberimmediatelywhenithasthedatasegment.ExperimentsshowthatCSMsignificantlyreducesthecontentdatatransmissionlatency.

  • 标签: 国际互联网 分布特点 流动特点 P2P技术
  • 简介:ThespectrumoftheΣ(1193)excitedstates,Σ,withisospinI=1andstrangenessS=??1isoneofthemostimportantissuesinhadronicphysics.TheΣresonancesaremostlyproducedandstudiedinK-inducedreactions.ManyΣresonancesarenowcatalogedbytheParticleDataGroup[1].However,ourknowledgeoftheseresonancesisstillverypoor.Intheenergyregionbelow2GeV,onlyafewofthemarewellestablished,suchastheΣ(1385)ofspin-parityJP=3=2+,Σ(1670)ofJp=3=2??andΣ(1775)ofJp=5=2??.Theothersarenotwellestablishedandsomeofthemareevenoflargeuncertaintiesontheirexistence.Thus,thestudyoftheΣresonancewiththeavailableexperimentaldataisnecessary.

  • 标签: EXPERIMENTAL Π now OUR is
  • 简介:FIRSTORDERQUASILINEAREQUATIONSINSEVERALINDEPENDENTVARIABLESWITHSINGULARINITIALDATAL~(P<∞)¥(赵会江)ZhaoHuijiang(YoungScientistLa?..

  • 标签: SINGULAR INITIAL DATA QUASILINEAR EQUATIONS global