简介：Introduction,Naccarellietal.reviewthefieldofstrokepreventioninatrialfibrillationandemphasizesthepointthatalargenumberofpatientsarenotanticoagulated[1].Innumeroustrials,NOACShavebeenshowntobebetterthanWarfarininreducingintracranialhemorrhageandhemorrhagicstrokeinpatientswithnon-valveatrialfibrilation[2].Butitisimportanttopointoutthattheabsoluteriskreductionissmall.AsfarasIcantell,notrialhascomparedNOACStoplacebo.Whereaswarfarinhasbeencomparedtoplaceboandhasbeenshowntobemarkedlyeffectiveasananticoagulanttopreventstroke.

简介：IntroductionAsIreflectbackonmytimeasaneditor,Irecallafewissuesthatbotheredmerelatingtopublicationsinmedicaljournals,e.g.Impactfactorandtherelationshipofeditorialsandself-citationontheimpactfactorandacceptanceratesfororiginalpublications.Whatfollowsaresomethoughtsonthesubject.

简介：Introduction,Anomalouscoronaryarteriesarefoundin0.1%–1.3%ofpatientsundergoingcoronaryangiography.AnomalouscoronaryarteriesareararebutimportantcauseofCP,arrhythmia,MI&suddencardiacdeath;andaretreatable.Angiographicevaluationcanbechallenging;misdiagnosiscanoccurinupto50%ofcases.Sometimestheseanomaliesaremissedbecauseoftheinexperienceoftheoperator.AnomalousCoronaryArteriescanbeassociatedwithcongenitalheartdiseaseorcanbeanisolatedanomaly.

简介：AlthoughanassociationbetweenthegroupAbetahemolyticstreptococcusandrheumaticfeverhasbeenrecognizedformorethanhalfacentury,manyimportantissuesaboutthisrelationshipremainincompletelydefined.Theinitiatingpharyngealthroatinfectionand