简介:【摘要】目的:对替硝唑与克林霉素治疗细菌性阴道炎的效果进行观察。方法:研究对象为2022年1月至2022年12月期间本院收治的130例细菌性阴道炎病患。采取随机分配法对其实施组别划分,其中65例为甲组,另65例为乙组。甲组行单独替硝唑治疗,乙组行替硝唑与克林霉素联合治疗。对比2组检出致病菌、乳酸杆菌概率以及症状消失时间。结果:乙组检出致病菌、乳酸杆菌概率比甲组低,症状消失时间比甲组短,P<0.05.结论:对细菌性阴道炎病患应用替硝唑与克林霉素联合治疗可获得良好效果,不仅能够降低致病菌、乳酸杆菌检出率,并且可以有效缩短病患症状的改善时间,对病患身体康复发挥着积极促进作用,可推广。
简介: 【摘要】目的:探究地高辛加倍他乐克用于治疗充血性心衰伴快速房颤的临床观察。方法:选择我院 2018年 3月至 2019年 3月收治的 78例充血性心衰伴快速房颤患者,采取随机分组的方法将患者分为对照组和实验组,每组 39例,所有患者在入院前均接受常规急救和护理,对照组患者将给予地高辛治疗,实验组患者将给予地高辛加倍他乐克治疗。然后对两组患者在治疗后的心率、左心室射血分数( LVEF)和总有效率进行对比。结果:在临床经过对比后发现,对照组患者的心率为( 89.3±11.4)次 /min,实验组患者的心率为( 78.6±8.9)次 /min,实验组患者在治疗后心率改善明显高于对照组,差异具有统计学意义( P<0.05) ;对照组患者的 LVEF( 43.1±2.3) %,实验组患者的 LVEF( 52.2±2.3) %,实验组患者的 LVEF相对于对照组更加接近正常水平,差异具有统计学意义( P<0.05) ;实验组患者的治疗总有效率为 97.43%( 38),对照组患者的治疗总有效率为 79.48%( 31),实验组患者的治疗总有效率明显高于对照组,差异具有统计学意义( P<0.05)。结论:对患者使用地高辛加倍他乐克临床效果更为显著,能有效降低患者心理和改善 LVEF水平,且不会增加患者不良反应,用药安全性高,值得在临床中推广。 【关键词】充血性心衰 ;快速房颤 ;倍他乐克 ;地高辛 Objective: To explore the clinical observation of digoxin and metoprolol in the treatment of congestive heart failure with rapid atrial fibrillation. Methods: 78 patients with congestive heart failure with rapid atrial fibrillation in our hospital from March 2018 to March 2019 were selected and randomly divided into control group and experimental group, 39 cases in each group. All patients received routine first aid and nursing before admission. Patients in the control group were given digoxin treatment, while patients in the experimental group were given digoxin treatment. Then the heart rate, left ventricular ejection fraction (LVEF) and total effective rate of the two groups were compared. Results: after clinical comparison, it was found that the heart rate of patients in the control group was (89.3 ± 11.4) beats / min, and the heart rate of patients in the experimental group was (78.6 ± 8.9) beats / min. the improvement of heart rate in the experimental group was significantly higher than that in the control group (P < 0.05); The LVEF of the control group was (43.1 ± 2.3)%, and that of the experimental group was (52.2 ± 2.3)%. The LVEF of the experimental group was closer to the normal level compared with the control group (P < 0.05); The total effective rate of the experimental group was 97.43% (38), and that of the control group was 79.48% (31). The total effective rate of the experimental group was significantly higher than that of the control group (P < 0.05). Conclusion: the clinical effect of digoxin double taloc is more significant, which can effectively reduce the psychological status of patients and improve the level of LVEF, and will not increase the adverse reactions of patients, so it is worthy of clinical promotion.
简介:【摘要】 目的 福多司坦联合支气管镜下肺泡灌洗治疗老年支气管扩张合并感染患者的疗效。方法 随机选取本院接收的老年支气管扩张合并感染患者60例,选取节点2019年6月-2020年6月,依照选取日期的不同分为2组,各30例。这中间,参照组(支气管镜下肺泡灌洗治疗),观察组(福多司坦联合支气管镜下肺泡灌洗治疗),对比两组临床效果、不良反应情况。结果 观察组临床效果好于参照组,差异显著(P<0.05)。观察组不良反应发生率低于参照组,差异显著(P<0.05)。结论 福多司坦联合支气管镜下肺泡灌洗治疗可提高临床效果,且不良反应相对较少,具有推广的价值。
简介: 【摘要】 目的 分析替诺福韦酯对核苷(酸)耐药的慢性乙型肝炎伴肝衰竭患者的临床效果。方法 60例对核苷(酸)耐药的慢性乙型肝炎伴肝衰竭患者, 随机分为对照组和观察组, 每组30例。对照组患者给予常规内科治疗, 观察组患者在对照组基础上给予富马酸替诺福韦二吡呋酯片治疗。观察比较两组患者乙肝病毒的脱氧核糖核酸(HBV-DNA)转阴率、治疗前后国际标准化比值(INR)、肝脏生化指标[总胆红素(TBIL)、总胆固醇(TC)、白蛋白(ALB)]、HBV-DNA载量及病死情况。結果 观察组患者HBV-DNA转阴率为50.00%(15/30), 高于对照组的13.33%(4/30), 差异具有统计学意义(P
简介: 【摘 要】目的:探究他克莫司与环磷酰胺治疗狼疮性肾炎的的效果和用药不良反应率。方法:纳入观察对象 40例(均确诊为狼疮性肾炎)进行实验研究,研究时间从 2015年 3月直至 2019年 5月。采用随机分组法,将观察对象分为甲乙两组,甲组 20例患儿使用他克莫司治疗,乙组 20例患儿采取环磷酰胺治疗。观察对比两组患儿治疗效果、不良反应发生情况。结果:甲组中 1例患儿疗效不明显,另外 19例均有改善,总有效率 95%;乙组中 5例疗效不明显, 1例病情恶化,另外 14例病情改善,总有效率 70%,两组间进行比较后得到 P<0.05。治疗后随访观察到,甲组患儿 1例出现尿痛的不良反应,乙组中有 6例,两组不良反应发生率的差异显著( P<0.05)。结论:狼疮性肾炎患儿在治疗过程中可应用他克莫司与环磷酰胺进行治疗,对比发现,他克莫司可以明显提升治疗的有效率,并且控制了患儿不良反应的出现,治疗安全性得到保障,临床应用效果理想,值得推广。 【关键词】他克莫司 ;环磷酰胺 ;狼疮性肾炎 ;效果 ;不良反应率 [Abstract] Objective: To explore the effect and adverse reaction rate of tacrolimus and cyclophosphamide in the treatment of lupus nephritis. Methods: 40 patients (all diagnosed as lupus nephritis) were included in the experimental study. The study period was from March 2015 to may 2019. The observation objects were randomly divided into two groups, group A (20 cases) was treated with tacrolimus, and group B (20 cases) was treated with cyclophosphamide. The treatment effect and adverse reactions of the two groups were observed and compared. Results: in group A, the curative effect of 1 case was not obvious, the other 19 cases were improved, the total effective rate was 95%; in group B, the curative effect was not obvious in 5 cases, 1 case was deteriorated, the other 14 cases were improved, the total effective rate was 70%, the comparison between the two groups showed that P < 0.05. After treatment, 1 case of adverse reactions occurred in group A and 6 cases in group B. There was a significant difference in the incidence of adverse reactions between the two groups (P < 0.05). Conclusion: tacrolimus and cyclophosphamide can be used in the treatment of children with lupus nephritis. Compared with cyclophosphamide, tacrolimus can significantly improve the efficiency of treatment, and control the occurrence of adverse reactions in children. The safety of treatment is guaranteed and the clinical application effect is ideal, which is worthy of promotion.
简介:【摘要】目的 分析富马酸替诺福韦二吡呋酯联合扶正柔肝方在乙肝肝纤维化治疗中的应用效果。方法 选取2019年3月-2019年12月本院80例乙肝肝纤维化患者,随机分为对照组(富马酸替诺福韦二吡呋酯)与观察组(富马酸替诺福韦二吡呋酯联合扶正柔肝方),对比两组治疗效果。结果 TBIL、ALB、ALT、AST、HA、LN、PC-Ⅲ、Ⅳ-C方面,观察组较对照组优(P