简介：Aims:Toinvestigatetheinfluenceofacupunctureoninsulinresistanceinobesitypatients.Methods:Intreatmentgroup,20obesitypatientsweretreatedwithacupunctureofNeiguan(PC6),Zusanli(ST36),Daimai(GB26),Sanyinjiao(SP6),Zhongwan(CV12),etc..Incontrolgroup,12normalvolunteersubjectswereobserved.Theobesityindex,fastingbloodsugar(FPG),plasmainsulin(FINS)andC-peptidecontents,andinsulinsensitiveindex(ISI)weremeasuredbeforeandafteracupuncturetreatment.Results:Beforetreatmentincomparisonwithcontrolgroup,FPG,FINSandC-peptideofobesitypatientsweresignificanthigher(P＜0.01),whileISIwasconsiderablylower(P＜0.01);afteracupuncturetreatment,thelevelsofplasmainsulinandCpeptidedecreasedobviously,ISIincreasedmarkedly(P＜0.01),andtheobesityindexwasconsiderablyimprovedwithatotaleffectiverateof85%.Conclusion:Acupuncturecanalleviateobesityandimproveinsulinresistance.

简介：Inrecentyears'stagedagger'typeshamneedlinghasbeenanticipatedtobeoneofthepossiblesolutionsformaskingpatientsinacupunctureresearch.Inordertoassessthevalidityofthistypeofneedling,weconductedtworandomized,single-blind,cross-overtrialswithacupuncture-experiencedsubjects.

简介：Theratfunctionalmaldigestionmodelwasmadebyirregularfeedingforstudyingmechanismsofacupunctureinregulatingrastroidtestinalactivities.ThechangesofthenumberandtheopticaldensityofNo-neuronsingastrointestinalintermuscularnerveswereusedastheindexes.Wistarratswererandomlydividedintoacupuncture,Domperidone,modelandcontrolgroupswithfourratsineachgroup.ThoseratswerefedwithDomperidome1mL/100g/dayatthebeginningofthemodelmakingprocess.Bilateral“Zusanli”(ST36)andright“Weishu”(BL21)werestimulatedfor20minineverysession,onceeverytwodays,continuouslyforonemonth.Onemonthlater,theratswerekilledforsamplingthegastrointestinalwalls.Thesampleswerecutintosectionswhichwerestainedwithimmunohistochemicalmethodforexaminingthenitricoxidesynthase(NOS)reactionwiththereductivecoenzymeⅡ.Theresultsshowedthatacupunctureof“Zusanli”and“Weishu”pointsmightrestoretheNOSactivityofthestomachtothenormallevel.Comparedwiththemodelgroup,Noimmuno-reactionpositiveneurons'numberinacupuncturegroupdecreasedandtheopticaldensityincreased.Theinfluenceofacupunctureontheupperpartofthesmallintestinewasindistinct.ChangesofNOIr-positiveneuronsmaycontributetotheeffectofacupunctureinmodulatinggastrointestinalactivitiesoffunctionalindigestioninclinic.

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简介：Thestudyhasexplored11correlativevariableswhichmightaffectthegallblad-derpressureGBPofpatientswithgallstoneafterauricularelectricalstimulationbymeansofmultiplestepwiseregression.Itwasfoundthatthesizeofgallbladderstone(X9),cholecystolithiasis(X4),sex(X1),andthebaselineofGBP(X10)couldaffecttheGBPchangerange(Y1)depressinglyorreinforcingly.AlsothebaselineofGBP(Y1)couldbeaffectedbythevariablesX1(sex),X2(age),andX6(longdiameterofthegallbladder,LDGB),etc..TheresultshowsthatthechangeinGBPafterauricularelectricalstimulationiscomprehensivelyinfluencedbymultiplefactors.Anditprovidessomeusefulinformationforpredictingthecurativeeffectofauriculartherapyongallbladderstoneinclinic.

简介：Objective:Toobservetheinfluenceofelectroacupuncture(EA)atdifferenttimeinadayonthenumberofduodenalendocrinecells(argentaffincells)inrats.Methods:Forty-eightmaleWistarratswereevenlyrandomizedintocontrolandelectroacupuncture(EA)groupswhichwerefurtherdividedinto5∶00,11∶00,17∶00and23∶00subgroupsrespectively.EA(4-16Hzinthefrequency,3Vinthestrength,intermittentdense-sparsewaves,anddurationof20min)wasappliedtobilateral"Huantiao"(环跳GB30)at5∶00o'clock,11∶00o'clock,17∶00o'clockand23∶00o'clockseparatelyfordifferentsubgroups.AfterEA,theanimalswerekilledatonceforsamplingthemiddlepartofduodenumwhichwasfixedin10%formalinfor2hours,thenembedinparaffin.Thetissuewascutintosections(10μm),mountedonglassslidesandthenprocessedaccordingtoGrimelius'smethods.Results:ThenumberofargentaffincellsinEAgroupwassignificantlyfewerthanthatincontrolgroupatthesametime-window(23∶00,P<0.05).NosignificantdifferenceswerefoundbetweencontrolandEAgroupsinthenumberofcellsatothertimewindow(5∶00,11∶00and17∶00o'clock,P>0.05),suggestingthatEAof"Huantiao"canmarkedlypromotethesecretionactivityofendocrinecellsat11∶00o'clockduringnight.Conclusion:TheresultssuggestthattheeffectsofEAaredifferentatdifferenttimewindowinaday.