摘要
摘要目的对两种四联疗法治疗幽门螺杆菌感染(Helicobacterpylori,Hp)消化性溃疡的效果进行比较和探讨.方法６０例幽门螺杆菌相关性消化性溃疡患者分为对照组和观察组,每组３０例.对照组应用雷呗拉唑、枸橼酸铋钾片、阿莫西林与克拉霉素治疗,观察组应用雷呗拉唑、枸橼酸铋钾片、阿莫西林与呋喃唑酮进行治疗.对采用不同四联疗法治疗的患者的临床疗效及幽门螺杆菌根除率进行比较.结果经治疗６周后,对照组有１２例治愈,１０例有效,８例无效,总有效率为７３．３％;观察组有１５例治愈,１３有效,２例无效,总有效率为９３．３３％.组间比较差异具有统计学意义(P＜０．０５).对照组HP根除率为８０％,观察组HP根除率为９３．３％,差异具有统计学意义(P＜０．０５).结论应用雷呗拉唑、枸橼酸铋钾片、阿莫西林与呋喃唑酮四联疗法治疗幽门螺杆菌相关性消化性溃疡,其治疗效果好于雷呗拉唑、枸橼酸铋钾片、阿莫西林与克拉霉素,可提高HP根除率,促进溃疡面愈合,值得临床推广使用.关键词幽门螺杆菌感染;消化性溃疡;含铋剂四联疗法TwokindsofquadrupletherapytheeradicationofHppositivecomparethecurativeeffectofpepticulcerLiuyajing(Beijingchangpingdistricthospital１０２２００)AbstractObjectiveTocomparedanddiscussedthetwokindsofquadrupletherapytreatmentofHelicobacterpyloriinfection(Helicobacterpylori,Hp)pepＧticulcereffects.Methods６０patientswithHpcorrelationofpepticulcerweredividedintocontrolgroupandobservationgroup,３０casesineachgroup.TheconＧtrolgroupusedraybaiazole,bismuthpotassiumcitratetablets,amoxicillinandclarithromycintreatment,Observationgroupusedraybaiazole,bismuthpotassiＧumcitratetablets,amoxicillinandfurazolidonetreatment,Toadoptdifferentquadrupletherapytotreatthepatient＇sclinicalcurativeeffectandhelicobacterpylorieradicationratecomparison．ResultAfter６weekstreatment,therewere１２caseswerecured,１０caseseffective,８casesofinvalidincontrolgroup,ThetotaleffecＧtiveratewas７３．３％;therewere１５caseswerecured,１３caseseffective,２casesofinvalidinobservationgroup,Thetotaleffectiveratewas９３．３％.Comparativedifferencesbetweengroupswithstatisticalsignificance(P＜０．０５)．ThecontrolgroupHperadicateratewas８０％,theobservationgroupHPeradicationratewas９３．３％,Statisticallysignificantdifference(P＜０．０５)．ConclusionUsedraybaiazole,bismuthpotassiumcitratetablets,amoxicillinandfurazolidonequadrupletherapyforhelicobacterpyloripepticulcer,Itstreatmenteffectisbetterthanraybaipullazole,bismuthpotassiumcitratetablets,amoxicillinandclarithromycin,CanimＧprovetKheeywHorPdseradicaterate,Promotehealingofulcersurface,isworthwideuseintheclinical．Helicobacterpyloriinfection;Pepticulcer;Containingbismuthagentquadrupletherapy中图分类号R５７３文献标识码A文献标识码B文章编号１００８－６３１５(２０１５)１２－１０６１－０２
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
