摘要
摘要目的对两种四联疗法治疗幽门螺杆菌感染(Helicobacterpylori,Hp)消化性溃疡的效果进行比较和探讨.方法60例幽门螺杆菌相关性消化性溃疡患者分为对照组和观察组,每组30例.对照组应用雷呗拉唑、枸橼酸铋钾片、阿莫西林与克拉霉素治疗,观察组应用雷呗拉唑、枸橼酸铋钾片、阿莫西林与呋喃唑酮进行治疗.对采用不同四联疗法治疗的患者的临床疗效及幽门螺杆菌根除率进行比较.结果经治疗6周后,对照组有12例治愈,10例有效,8例无效,总有效率为73.3%;观察组有15例治愈,13有效,2例无效,总有效率为93.33%.组间比较差异具有统计学意义(P<0.05).对照组HP根除率为80%,观察组HP根除率为93.3%,差异具有统计学意义(P<0.05).结论应用雷呗拉唑、枸橼酸铋钾片、阿莫西林与呋喃唑酮四联疗法治疗幽门螺杆菌相关性消化性溃疡,其治疗效果好于雷呗拉唑、枸橼酸铋钾片、阿莫西林与克拉霉素,可提高HP根除率,促进溃疡面愈合,值得临床推广使用.关键词幽门螺杆菌感染;消化性溃疡;含铋剂四联疗法TwokindsofquadrupletherapytheeradicationofHppositivecomparethecurativeeffectofpepticulcerLiuyajing(Beijingchangpingdistricthospital102200)AbstractObjectiveTocomparedanddiscussedthetwokindsofquadrupletherapytreatmentofHelicobacterpyloriinfection(Helicobacterpylori,Hp)pepGticulcereffects.Methods60patientswithHpcorrelationofpepticulcerweredividedintocontrolgroupandobservationgroup,30casesineachgroup.TheconGtrolgroupusedraybaiazole,bismuthpotassiumcitratetablets,amoxicillinandclarithromycintreatment,Observationgroupusedraybaiazole,bismuthpotassiGumcitratetablets,amoxicillinandfurazolidonetreatment,Toadoptdifferentquadrupletherapytotreatthepatient'sclinicalcurativeeffectandhelicobacterpylorieradicationratecomparison.ResultAfter6weekstreatment,therewere12caseswerecured,10caseseffective,8casesofinvalidincontrolgroup,ThetotaleffecGtiveratewas73.3%;therewere15caseswerecured,13caseseffective,2casesofinvalidinobservationgroup,Thetotaleffectiveratewas93.3%.Comparativedifferencesbetweengroupswithstatisticalsignificance(P<0.05).ThecontrolgroupHperadicateratewas80%,theobservationgroupHPeradicationratewas93.3%,Statisticallysignificantdifference(P<0.05).ConclusionUsedraybaiazole,bismuthpotassiumcitratetablets,amoxicillinandfurazolidonequadrupletherapyforhelicobacterpyloripepticulcer,Itstreatmenteffectisbetterthanraybaipullazole,bismuthpotassiumcitratetablets,amoxicillinandclarithromycin,CanimGprovetKheeywHorPdseradicaterate,Promotehealingofulcersurface,isworthwideuseintheclinical.Helicobacterpyloriinfection;Pepticulcer;Containingbismuthagentquadrupletherapy中图分类号R573文献标识码A文献标识码B文章编号1008-6315(2015)12-1061-02
出版日期
2015年12月22日(中国期刊网平台首次上网日期,不代表论文的发表时间)