摘要
Toobservetheeffectsofdifferentacupuncturemanipulationsonbloodpressureandtargetorgandamageinspontaneouslyhypertensiverats(SHRs),thisstudyusedthereinforcingtwirlingmethod(1.5–2-mmdepth;rotatingneedleclockwisefor360°andthencounterclockwisefor360°,withthethumbmovingheavilyforwardandgentlybackward,60timesperminutefor1minute,andretainingneedlefor9minutes),thereducingtwirlingmethod(1.5–2-mmdepth;rotatingneedlecounterclockwisefor360°andthenclockwisefor360°,withthethumbmovingheavilybackwardandgentlyforward,60timesperminutefor1minute,andretainingneedlefor9minutes),andtheneedleretainingmethod(1.5–2-mmdepthandretainingtheneedlefor10minutes).BilateralTaichong(LR3)wastreatedbyacupunctureusingdifferentmanipulationsandmanualstimulation.Reinforcingtwirling,reducingtwirling,andneedleretainingresultedinadecreasednumberofapoptoticcells,reducedBaxmRNAandproteinexpression,andanincreasedBcl-2/BaxratiointhehippocampuscomparedwiththeSHRgroup.Amongthesegroups,theBcl-2/Baxproteinratiowashighestinthereducingtwirlinggroup,andtheBcl-2/BaxmRNAratiowashighestintheneedleretaininggroup.Theseresultssuggestthatreinforcingtwirling,reducingtwirling,andneedleretainingmethodsallimprovebloodpressureandpreventtargetorgandamagebyincreasingthehippocampalBcl-2/BaxratioandinhibitingcellapoptosisinthehippocampusinSHR.
出版日期
2017年05月15日（中国期刊网平台首次上网日期，不代表论文的发表时间）
