Asian trends in primary androgen depletion therapy on prostate cancer

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摘要 TherearenotabledifferencesintheincidenceandmortalityratesforprostatecancerbetweenAsiaandWesterncountries.Itisalsorecognizedthattherearedifferencesinthinkingwithregardtotreatmentoptions.RecentlyitisalsothecasethatopinionshavebeenreportedconcerningthedifferencesbetweenAsianandWesternpatientswithregardtotheirreactiontoandrogendepletiontherapy(ADT).GiventhatADTisamethodoftreatmentthatfocusesontheeliminationoftestosterone,aninevitablesymptomofitsadministrationistestosteronelosingsyndrome.ItisforthisreasonthatinWesterncountriesADThasonlybeenrecommendedincasesofadvancedormetastaticcancer.Ontheotherhand,inAsia,ADTisusedinrelativelymanycases,includingnon-metastaticlocalizedcancerandinvasivelocalizedcancer.Todate,however,therehasbeenlittlesubstantivediscussionconcerningthisdifferenceinutilizationofADT.ADT-relateddrugsforprostatecancerandthedevelopmentofnewdrugsforcastrationresistantprostatecancer(CRPC)havebeenactivelytestedinrecentyears.ItcouldbethecasethatanalyzingthedifferencesinconceptsaboutADTbetweenAsiaandtheWestcouldcontributetotheeffectiveuseofADT-relateddrugsandalsohelptobuildnewtreatmentstrategiesforprostatecancer.
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出版日期 2013年04月14日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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