摘要
ToexplorethepolysaccharidesfromselectedseaweedsofAtlanticCanadaandtoevaluatetheirpotentialanti-influenzavirusactivities,polysaccharideswereisolatedfromseveralAtlanticCanadianseaweeds,includingthreeredalgae(Polysiphonialanosa,Furcellarialumbricalis,andPalmariapalmata),twobrownalgae(AscophyllumnodosumandFucusvesiculosus),andonegreenalga(Ulvalactuca)bysequentialextractionwithcoldwater,hotwater,andalkalisolutions.Thesepolysaccharideswereana-lyzedformonosaccharidecompositionandothergeneralchemicalproperties,andtheywereevaluatedforanti-influenzavirusactivities.Totalsugarcontentsinthesepolysaccharidesrangedfrom15.4%(inU.lactuca)to91.4%(inF.lumbricalis);sulfationlevelwasashighas17.6%inapolysaccharidefromU.lactuca,whereasitcouldnotbedetectedinanalikali-extractfromP.palmaria.Forpolysaccharidesfromredseaweeds,themainsugarunitsweresulfatedgalactans(agarorcarrageenan)forP.lanosa,F.lumbricalis,andxylansforP.palmata.Inbrownseaweeds,thepolysaccharideslargelycontainedsulfatedfucans,whereasthepolysaccharidesingreenseaweedweremainlycomposedofheteroglycuronans.ScreeningforantiviralactivityagainstinfluenzaA/PR/8/34(H1N1)virusrevealedthatbrownalgalpolysaccharideswereparticularlyeffective.SeaweedsfromAtlanticCanadaareagoodsourceofmarinepolysaccharideswithpotentialantiviralproperties.
出版日期
2012年02月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
